TopFIND 4.0

O60779: Thiamine transporter 1

General Information

Protein names
- Thiamine transporter 1
- ThTr-1
- ThTr1
- Solute carrier family 19 member 2
- Thiamine carrier 1
- TC1
Gene names SLC19A2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O60779

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDVPGPVSRR AAAAAATVLL RTARVRRECW FLPTALLCAY GFFASLRPSE PFLTPYLLGP 
        70         80         90        100        110        120 
DKNLTEREVF NEIYPVWTYS YLVLLFPVFL ATDYLRYKPV VLLQGLSLIV TWFMLLYAQG 
       130        140        150        160        170        180 
LLAIQFLEFF YGIATATEIA YYSYIYSVVD LGMYQKVTSY CRSATLVGFT VGSVLGQILV 
       190        200        210        220        230        240 
SVAGWSLFSL NVISLTCVSV AFAVAWFLPM PQKSLFFHHI PSTCQRVNGI KVQNGGIVTD 
       250        260        270        280        290        300 
TPASNHLPGW EDIESKIPLN MEEPPVEEPE PKPDRLLVLK VLWNDFLMCY SSRPLLCWSV 
       310        320        330        340        350        360 
WWALSTCGYF QVVNYTQGLW EKVMPSRYAA IYNGGVEAVS TLLGAVAVFA VGYIKISWST 
       370        380        390        400        410        420 
WGEMTLSLFS LLIAAAVYIM DTVGNIWVCY ASYVVFRIIY MLLITIATFQ IAANLSMERY 
       430        440        450        460        470        480 
ALVFGVNTFI ALALQTLLTL IVVDASGLGL EITTQFLIYA SYFALIAVVF LASGAVSVMK 
       490    
KCRKLEDPQS SSQVTTS

Isoforms

- Isoform 2 of Thiamine transporter 1

Sequence View

        10         20         30         40         50         60 
MDVPGPVSRR AAAAAATVLL RTARVRRECW FLPTALLCAY GFFASLRPSE PFLTPYLLGP 
        70         80         90        100        110        120 
DKNLTEREVF NEIYPVWTYS YLVLLFPVFL ATDYLRYKPV VLLQGLSLIV TWFMLLYAQG 
       130        140        150        160        170        180 
LLAIQFLEFF YGIATATEIA YYSYIYSVVD LGMYQKVTSY CRSATLVGFT VGSVLGQILV 
       190        200        210        220        230        240 
SVAGWSLFSL NVISLTCVSV AFAVAWFLPM PQKSLFFHHI PSTCQRVNGI KVQNGGIVTD 
       250        260        270        280        290        300 
TPASNHLPGW EDIESKIPLN MEEPPVEEPE PKPDRLLVLK VLWNDFLMCY SSRPLLCWSV 
       310        320        330        340        350        360 
WWALSTCGYF QVVNYTQGLW EKVMPSRYAA IYNGGVEAVS TLLGAVAVFA VGYIKISWST 
       370        380        390        400        410        420 
WGEMTLSLFS LLIAAAVYIM DTVGNIWVCY ASYVVFRIIY MLLITIATFQ IAANLSMERY 
       430        440        450        460        470        480 
ALVFGVNTFI ALALQTLLTL IVVDASGLGL EITTQFLIYA SYFALIAVVF LASGAVSVMK 
       490    
KCRKLEDPQS SSQVTTS



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O60779-1-Acetylation MDVPGP... 1 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    O60779-1-Acetylation MDVPGP... 1 acetylation- inferred from isoform by sequence similarity unknown TopFIND inferred from TNt105915
    O60779-1-unknown MDVPGP... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt88532

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...QVTTS 497 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...QVTTS 497 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt84150

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)