O60941: Dystrobrevin beta

General Information

Protein names	- Dystrobrevin beta - DTN-B - Beta-dystrobrevin
Gene names	DTNB
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O60941

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Dystrobrevin beta - Isoform 3 of Dystrobrevin beta - Isoform 4 of Dystrobrevin beta - Isoform 5 of Dystrobrevin beta - Isoform 6 of Dystrobrevin beta - Isoform 7 of Dystrobrevin beta

Sequence View

        10         20         30         40         50         60
MIEESGNKRK TMAEKRQLFI EMRAQNFDVI RLSTYRTACK LRFVQKRCNL HLVDIWNMIE
        70         80         90        100        110        120
AFRDNGLNTL DHTTEISVSR LETVISSIYY QLNKRLPSTH QISVEQSISL LLNFMIAAYD
       130        140        150        160        170        180
SEGRGKLTVF SVKAMLATMC GGKMLDKLRY VFSQMSDSNG LMIFSKFDQF LKEVLKLPTA
       190        200        210        220        230        240
VFEGPSFGYT EHSVRTCFPQ QRKIMLNMFL DTMMADPPPQ CLVWLPLMHR LAHVENVFHP
       250        260        270        280        290        300
VECSYCRCES MMGFRYRCQQ CHNYQLCQNC FWRGHAGGPH SNQHQMKEHS SWKSPAKKLS
       310        320        330        340        350        360
HAISKSLGCV PTREPPHPVF PEQPEKPLDL AHIVPPRPLT NMNDTMVSHM SSGVPTPTKR
       370        380        390        400        410        420
LQYSQDIPSH LADEHALIAS YVARLQHCAR VLDSPSRLDE EHRLIARYAA RLAAEAGNVT
       430        440        450        460        470        480
RPPTDLSFNF DANKQQRQLI AELENKNREI LQEIQRLRLE HEQASQPTPE KAQQNPTLLA
       490        500        510        520        530        540
ELRLLRQRKD ELEQRMSALQ ESRRELMVQL EELMKLLKEE EQKQAAQATG SPHTSPTHGG
       550        560        570        580        590        600
GRPMPMPVRS TSAGSTPTHC PQDSLSGVGG DVQEAFAQGT RRNLRNDLLV AADSITNTMS
       610        620
SLVKELHSAE EGAEEEEEKM QNGKDRG         10         20         30         40         50         60
MIEESGNKRK TMAEKRQLFI EMRAQNFDVI RLSTYRTACK LRFVQKRCNL HLVDIWNMIE
        70         80         90        100        110        120
AFRDNGLNTL DHTTEISVSR LETVISSIYY QLNKRLPSTH QISVEQSISL LLNFMIAAYD
       130        140        150        160        170        180
SEGRGKLTVF SVKAMLATMC GGKMLDKLRY VFSQMSDSNG LMIFSKFDQF LKEVLKLPTA
       190        200        210        220        230        240
VFEGPSFGYT EHSVRTCFPQ QRKIMLNMFL DTMMADPPPQ CLVWLPLMHR LAHVENVFHP
       250        260        270        280        290        300
VECSYCRCES MMGFRYRCQQ CHNYQLCQNC FWRGHAGGPH SNQHQMKEHS SWKSPAKKLS
       310        320        330        340        350        360
HAISKSLGCV PTREPPHPVF PEQPEKPLDL AHIVPPRPLT NMNDTMVSHM SSGVPTPTKR
       370        380        390        400        410        420
LQYSQDIPSH LADEHALIAS YVARLQHCAR VLDSPSRLDE EHRLIARYAA RLAAEAGNVT
       430        440        450        460        470        480
RPPTDLSFNF DANKQQRQLI AELENKNREI LQEIQRLRLE HEQASQPTPE KAQQNPTLLA
       490        500        510        520        530        540
ELRLLRQRKD ELEQRMSALQ ESRRELMVQL EELMKLLKEE EQKQAAQATG SPHTSPTHGG
       550        560        570        580        590        600
GRPMPMPVRS TSAGSTPTHC PQDSLSGVGG DVQEAFAQGT RRNLRNDLLV AADSITNTMS
       610        620
SLVKELHSAE EGAEEEEEKM QNGKDRG         10         20         30         40         50         60
MIEESGNKRK TMAEKRQLFI EMRAQNFDVI RLSTYRTACK LRFVQKRCNL HLVDIWNMIE
        70         80         90        100        110        120
AFRDNGLNTL DHTTEISVSR LETVISSIYY QLNKRLPSTH QISVEQSISL LLNFMIAAYD
       130        140        150        160        170        180
SEGRGKLTVF SVKAMLATMC GGKMLDKLRY VFSQMSDSNG LMIFSKFDQF LKEVLKLPTA
       190        200        210        220        230        240
VFEGPSFGYT EHSVRTCFPQ QRKIMLNMFL DTMMADPPPQ CLVWLPLMHR LAHVENVFHP
       250        260        270        280        290        300
VECSYCRCES MMGFRYRCQQ CHNYQLCQNC FWRGHAGGPH SNQHQMKEHS SWKSPAKKLS
       310        320        330        340        350        360
HAISKSLGCV PTREPPHPVF PEQPEKPLDL AHIVPPRPLT NMNDTMVSHM SSGVPTPTKR
       370        380        390        400        410        420
LQYSQDIPSH LADEHALIAS YVARLQHCAR VLDSPSRLDE EHRLIARYAA RLAAEAGNVT
       430        440        450        460        470        480
RPPTDLSFNF DANKQQRQLI AELENKNREI LQEIQRLRLE HEQASQPTPE KAQQNPTLLA
       490        500        510        520        530        540
ELRLLRQRKD ELEQRMSALQ ESRRELMVQL EELMKLLKEE EQKQAAQATG SPHTSPTHGG
       550        560        570        580        590        600
GRPMPMPVRS TSAGSTPTHC PQDSLSGVGG DVQEAFAQGT RRNLRNDLLV AADSITNTMS
       610        620
SLVKELHSAE EGAEEEEEKM QNGKDRG         10         20         30         40         50         60
MIEESGNKRK TMAEKRQLFI EMRAQNFDVI RLSTYRTACK LRFVQKRCNL HLVDIWNMIE
        70         80         90        100        110        120
AFRDNGLNTL DHTTEISVSR LETVISSIYY QLNKRLPSTH QISVEQSISL LLNFMIAAYD
       130        140        150        160        170        180
SEGRGKLTVF SVKAMLATMC GGKMLDKLRY VFSQMSDSNG LMIFSKFDQF LKEVLKLPTA
       190        200        210        220        230        240
VFEGPSFGYT EHSVRTCFPQ QRKIMLNMFL DTMMADPPPQ CLVWLPLMHR LAHVENVFHP
       250        260        270        280        290        300
VECSYCRCES MMGFRYRCQQ CHNYQLCQNC FWRGHAGGPH SNQHQMKEHS SWKSPAKKLS
       310        320        330        340        350        360
HAISKSLGCV PTREPPHPVF PEQPEKPLDL AHIVPPRPLT NMNDTMVSHM SSGVPTPTKR
       370        380        390        400        410        420
LQYSQDIPSH LADEHALIAS YVARLQHCAR VLDSPSRLDE EHRLIARYAA RLAAEAGNVT
       430        440        450        460        470        480
RPPTDLSFNF DANKQQRQLI AELENKNREI LQEIQRLRLE HEQASQPTPE KAQQNPTLLA
       490        500        510        520        530        540
ELRLLRQRKD ELEQRMSALQ ESRRELMVQL EELMKLLKEE EQKQAAQATG SPHTSPTHGG
       550        560        570        580        590        600
GRPMPMPVRS TSAGSTPTHC PQDSLSGVGG DVQEAFAQGT RRNLRNDLLV AADSITNTMS
       610        620
SLVKELHSAE EGAEEEEEKM QNGKDRG         10         20         30         40         50         60
MIEESGNKRK TMAEKRQLFI EMRAQNFDVI RLSTYRTACK LRFVQKRCNL HLVDIWNMIE
        70         80         90        100        110        120
AFRDNGLNTL DHTTEISVSR LETVISSIYY QLNKRLPSTH QISVEQSISL LLNFMIAAYD
       130        140        150        160        170        180
SEGRGKLTVF SVKAMLATMC GGKMLDKLRY VFSQMSDSNG LMIFSKFDQF LKEVLKLPTA
       190        200        210        220        230        240
VFEGPSFGYT EHSVRTCFPQ QRKIMLNMFL DTMMADPPPQ CLVWLPLMHR LAHVENVFHP
       250        260        270        280        290        300
VECSYCRCES MMGFRYRCQQ CHNYQLCQNC FWRGHAGGPH SNQHQMKEHS SWKSPAKKLS
       310        320        330        340        350        360
HAISKSLGCV PTREPPHPVF PEQPEKPLDL AHIVPPRPLT NMNDTMVSHM SSGVPTPTKR
       370        380        390        400        410        420
LQYSQDIPSH LADEHALIAS YVARLQHCAR VLDSPSRLDE EHRLIARYAA RLAAEAGNVT
       430        440        450        460        470        480
RPPTDLSFNF DANKQQRQLI AELENKNREI LQEIQRLRLE HEQASQPTPE KAQQNPTLLA
       490        500        510        520        530        540
ELRLLRQRKD ELEQRMSALQ ESRRELMVQL EELMKLLKEE EQKQAAQATG SPHTSPTHGG
       550        560        570        580        590        600
GRPMPMPVRS TSAGSTPTHC PQDSLSGVGG DVQEAFAQGT RRNLRNDLLV AADSITNTMS
       610        620
SLVKELHSAE EGAEEEEEKM QNGKDRG         10         20         30         40         50         60
MIEESGNKRK TMAEKRQLFI EMRAQNFDVI RLSTYRTACK LRFVQKRCNL HLVDIWNMIE
        70         80         90        100        110        120
AFRDNGLNTL DHTTEISVSR LETVISSIYY QLNKRLPSTH QISVEQSISL LLNFMIAAYD
       130        140        150        160        170        180
SEGRGKLTVF SVKAMLATMC GGKMLDKLRY VFSQMSDSNG LMIFSKFDQF LKEVLKLPTA
       190        200        210        220        230        240
VFEGPSFGYT EHSVRTCFPQ QRKIMLNMFL DTMMADPPPQ CLVWLPLMHR LAHVENVFHP
       250        260        270        280        290        300
VECSYCRCES MMGFRYRCQQ CHNYQLCQNC FWRGHAGGPH SNQHQMKEHS SWKSPAKKLS
       310        320        330        340        350        360
HAISKSLGCV PTREPPHPVF PEQPEKPLDL AHIVPPRPLT NMNDTMVSHM SSGVPTPTKR
       370        380        390        400        410        420
LQYSQDIPSH LADEHALIAS YVARLQHCAR VLDSPSRLDE EHRLIARYAA RLAAEAGNVT
       430        440        450        460        470        480
RPPTDLSFNF DANKQQRQLI AELENKNREI LQEIQRLRLE HEQASQPTPE KAQQNPTLLA
       490        500        510        520        530        540
ELRLLRQRKD ELEQRMSALQ ESRRELMVQL EELMKLLKEE EQKQAAQATG SPHTSPTHGG
       550        560        570        580        590        600
GRPMPMPVRS TSAGSTPTHC PQDSLSGVGG DVQEAFAQGT RRNLRNDLLV AADSITNTMS
       610        620
SLVKELHSAE EGAEEEEEKM QNGKDRG

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O60941-1-unknown	MIEESG...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O60941-1-unknown	MIEESG...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt73323
O60941-1-unknown	MIEESG...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt73324
O60941-1-unknown	MIEESG...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt73325
O60941-1-unknown	MIEESG...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt73326
O60941-1-unknown	MIEESG...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt73328
O60941-1-unknown	MIEESG...	1		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
O60941-58-unknown	MIEAFR...	58	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt73327
O60941-58-unknown	MIEAFR...	58	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt102185
O60941-58-unknown	MIEAFR...	58	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt102186
O60941-58-unknown	MIEAFR...	58	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt102187
O60941-58-unknown	MIEAFR...	58	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt102188
O60941-58-unknown	MIEAFR...	58	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt102189

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...GKDRG	627	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)