O60942: mRNA-capping enzyme

General Information

Protein names	- mRNA-capping enzyme - HCAP1 - HCE - Polynucleotide 5'-triphosphatase - 3.1.3.33 - mRNA 5'-triphosphatase - TPase - mRNA guanylyltransferase - 2.7.7.50 - GTP--RNA guanylyltransferase - GTase
Gene names	RNGTT
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O60942

1 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAHNKIPPRW LNCPRRGQPV AGRFLPLKTM LGPRYDSQVA EENRFHPSML SNYLKSLKVK
        70         80         90        100        110        120
MGLLVDLTNT SRFYDRNDIE KEGIKYIKLQ CKGHGECPTT ENTETFIRLC ERFNERNPPE
       130        140        150        160        170        180
LIGVHCTHGF NRTGFLICAF LVEKMDWSIE AAVATFAQAR PPGIYKGDYL KELFRRYGDI
       190        200        210        220        230        240
EEAPPPPLLP DWCFEDDEDE DEDEDGKKES EPGSSASFGK RRKERLKLGA IFLEGVTVKG
       250        260        270        280        290        300
VTQVTTQPKL GEVQQKCHQF CGWEGSGFPG AQPVSMDKQN IKLLDLKPYK VSWKADGTRY
       310        320        330        340        350        360
MMLIDGTNEV FMIDRDNSVF HVSNLEFPFR KDLRMHLSNT LLDGEMIIDR VNGQAVPRYL
       370        380        390        400        410        420
IYDIIKFNSQ PVGDCDFNVR LQCIEREIIS PRHEKMKTGL IDKTQEPFSV RNKPFFDICT
       430        440        450        460        470        480
SRKLLEGNFA KEVSHEMDGL IFQPTGKYKP GRCDDILKWK PPSLNSVDFR LKITRMGGEG
       490        500        510        520        530        540
LLPQNVGLLY VGGYERPFAQ IKVTKELKQY DNKIIECKFE NNSWVFMRQR TDKSFPNAYN
       550        560        570        580        590
TAMAVCNSIS NPVTKEMLFE FIDRCTAASQ GQKRKHHLDP DTELMPPPPP KRPRPLT

Isoforms

- Isoform 2 of mRNA-capping enzyme - Isoform 3 of mRNA-capping enzyme - Isoform 4 of mRNA-capping enzyme

Sequence View

        10         20         30         40         50         60
MAHNKIPPRW LNCPRRGQPV AGRFLPLKTM LGPRYDSQVA EENRFHPSML SNYLKSLKVK
        70         80         90        100        110        120
MGLLVDLTNT SRFYDRNDIE KEGIKYIKLQ CKGHGECPTT ENTETFIRLC ERFNERNPPE
       130        140        150        160        170        180
LIGVHCTHGF NRTGFLICAF LVEKMDWSIE AAVATFAQAR PPGIYKGDYL KELFRRYGDI
       190        200        210        220        230        240
EEAPPPPLLP DWCFEDDEDE DEDEDGKKES EPGSSASFGK RRKERLKLGA IFLEGVTVKG
       250        260        270        280        290        300
VTQVTTQPKL GEVQQKCHQF CGWEGSGFPG AQPVSMDKQN IKLLDLKPYK VSWKADGTRY
       310        320        330        340        350        360
MMLIDGTNEV FMIDRDNSVF HVSNLEFPFR KDLRMHLSNT LLDGEMIIDR VNGQAVPRYL
       370        380        390        400        410        420
IYDIIKFNSQ PVGDCDFNVR LQCIEREIIS PRHEKMKTGL IDKTQEPFSV RNKPFFDICT
       430        440        450        460        470        480
SRKLLEGNFA KEVSHEMDGL IFQPTGKYKP GRCDDILKWK PPSLNSVDFR LKITRMGGEG
       490        500        510        520        530        540
LLPQNVGLLY VGGYERPFAQ IKVTKELKQY DNKIIECKFE NNSWVFMRQR TDKSFPNAYN
       550        560        570        580        590
TAMAVCNSIS NPVTKEMLFE FIDRCTAASQ GQKRKHHLDP DTELMPPPPP KRPRPLT         10         20         30         40         50         60
MAHNKIPPRW LNCPRRGQPV AGRFLPLKTM LGPRYDSQVA EENRFHPSML SNYLKSLKVK
        70         80         90        100        110        120
MGLLVDLTNT SRFYDRNDIE KEGIKYIKLQ CKGHGECPTT ENTETFIRLC ERFNERNPPE
       130        140        150        160        170        180
LIGVHCTHGF NRTGFLICAF LVEKMDWSIE AAVATFAQAR PPGIYKGDYL KELFRRYGDI
       190        200        210        220        230        240
EEAPPPPLLP DWCFEDDEDE DEDEDGKKES EPGSSASFGK RRKERLKLGA IFLEGVTVKG
       250        260        270        280        290        300
VTQVTTQPKL GEVQQKCHQF CGWEGSGFPG AQPVSMDKQN IKLLDLKPYK VSWKADGTRY
       310        320        330        340        350        360
MMLIDGTNEV FMIDRDNSVF HVSNLEFPFR KDLRMHLSNT LLDGEMIIDR VNGQAVPRYL
       370        380        390        400        410        420
IYDIIKFNSQ PVGDCDFNVR LQCIEREIIS PRHEKMKTGL IDKTQEPFSV RNKPFFDICT
       430        440        450        460        470        480
SRKLLEGNFA KEVSHEMDGL IFQPTGKYKP GRCDDILKWK PPSLNSVDFR LKITRMGGEG
       490        500        510        520        530        540
LLPQNVGLLY VGGYERPFAQ IKVTKELKQY DNKIIECKFE NNSWVFMRQR TDKSFPNAYN
       550        560        570        580        590
TAMAVCNSIS NPVTKEMLFE FIDRCTAASQ GQKRKHHLDP DTELMPPPPP KRPRPLT         10         20         30         40         50         60
MAHNKIPPRW LNCPRRGQPV AGRFLPLKTM LGPRYDSQVA EENRFHPSML SNYLKSLKVK
        70         80         90        100        110        120
MGLLVDLTNT SRFYDRNDIE KEGIKYIKLQ CKGHGECPTT ENTETFIRLC ERFNERNPPE
       130        140        150        160        170        180
LIGVHCTHGF NRTGFLICAF LVEKMDWSIE AAVATFAQAR PPGIYKGDYL KELFRRYGDI
       190        200        210        220        230        240
EEAPPPPLLP DWCFEDDEDE DEDEDGKKES EPGSSASFGK RRKERLKLGA IFLEGVTVKG
       250        260        270        280        290        300
VTQVTTQPKL GEVQQKCHQF CGWEGSGFPG AQPVSMDKQN IKLLDLKPYK VSWKADGTRY
       310        320        330        340        350        360
MMLIDGTNEV FMIDRDNSVF HVSNLEFPFR KDLRMHLSNT LLDGEMIIDR VNGQAVPRYL
       370        380        390        400        410        420
IYDIIKFNSQ PVGDCDFNVR LQCIEREIIS PRHEKMKTGL IDKTQEPFSV RNKPFFDICT
       430        440        450        460        470        480
SRKLLEGNFA KEVSHEMDGL IFQPTGKYKP GRCDDILKWK PPSLNSVDFR LKITRMGGEG
       490        500        510        520        530        540
LLPQNVGLLY VGGYERPFAQ IKVTKELKQY DNKIIECKFE NNSWVFMRQR TDKSFPNAYN
       550        560        570        580        590
TAMAVCNSIS NPVTKEMLFE FIDRCTAASQ GQKRKHHLDP DTELMPPPPP KRPRPLT

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O60942-1-unknown	MAHNKI...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O60942-1-unknown	MAHNKI...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt80598
O60942-1-unknown	MAHNKI...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt80599
O60942-1-unknown	MAHNKI...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt80600

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...MGGEGL	480	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76217
...MGGEGL	480	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92823
...MGGEGL	480	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92822
...PRPLT	597	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...PRPLT	597	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76216

TopFIND

O60942: mRNA-capping enzyme

General Information

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates