TopFIND 4.0

O70143: SHC-transforming protein 3

General Information

Protein names
- SHC-transforming protein 3
- Neuronal Shc
- N-Shc
- SHC-transforming protein C
- Src homology 2 domain-containing-transforming protein C3
- SH2 domain protein C3
Gene names Shc3
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID O70143

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLPRTKYNRF RNDSVTSVDD LLHSLSVSGS GGKVSAEPAA SPYLVSGEAL RKAPDDGPGS 
        70         80         90        100        110        120 
LGHLLHKVSH LKLSSSGLRG LSSAARERAG ARLSGSCSAP SLAAPDGGSA TPGSRAPAAS 
       130        140        150        160        170        180 
MSATRKSRAS DEPLPRPPRG APHASDQVLG SGVTYVVKYL GCIEVLRSMR SLDFSTRTQV 
       190        200        210        220        230        240 
TREAISRVCE AVPGAKGAFK KRKPPSKMLS SILGKSNLQF AGMSISLTIS TASLNLRTPD 
       250        260        270        280        290        300 
SKQIISNHHM RSISFASGGD PDTTDYVAYV AKDPVNRRAC HILECCDGLA QDVIGSIGQA 
       310        320        330        340        350        360 
FELRFKQYLQ CPSKIPALQD RMQSLDEPWT EEEGDGPDHP YYNSVPNKMP PPGGFLDARL 
       370        380        390        400        410        420 
KARPHAPDAA QFSGKEQTYY QGRHLGDAFG EDWQRAPTRQ GSLDIYSTPE GKAHMVPVGE 
       430        440        450        460        470        480 
TPTYVNTQPV PPQVWPAATS STESSPRKDL FDMKPFEDAL RNQPLGPVLS KAASVECISP 
       490        500        510        520        530        540 
VTPRAPDAKM LEELNAEPWY QGEMSRKEAE ALLQEDGDFL VRKSTTNPGS FVLTGMHNGQ 
       550        560        570        580        590    
AKHLLLVDPE GTVRTKDRVF DSISHLITYH LESSLPIVSA GSELCLRQPV ERKP

Isoforms

- Isoform p52 of SHC-transforming protein 3

Sequence View

        10         20         30         40         50         60 
MLPRTKYNRF RNDSVTSVDD LLHSLSVSGS GGKVSAEPAA SPYLVSGEAL RKAPDDGPGS 
        70         80         90        100        110        120 
LGHLLHKVSH LKLSSSGLRG LSSAARERAG ARLSGSCSAP SLAAPDGGSA TPGSRAPAAS 
       130        140        150        160        170        180 
MSATRKSRAS DEPLPRPPRG APHASDQVLG SGVTYVVKYL GCIEVLRSMR SLDFSTRTQV 
       190        200        210        220        230        240 
TREAISRVCE AVPGAKGAFK KRKPPSKMLS SILGKSNLQF AGMSISLTIS TASLNLRTPD 
       250        260        270        280        290        300 
SKQIISNHHM RSISFASGGD PDTTDYVAYV AKDPVNRRAC HILECCDGLA QDVIGSIGQA 
       310        320        330        340        350        360 
FELRFKQYLQ CPSKIPALQD RMQSLDEPWT EEEGDGPDHP YYNSVPNKMP PPGGFLDARL 
       370        380        390        400        410        420 
KARPHAPDAA QFSGKEQTYY QGRHLGDAFG EDWQRAPTRQ GSLDIYSTPE GKAHMVPVGE 
       430        440        450        460        470        480 
TPTYVNTQPV PPQVWPAATS STESSPRKDL FDMKPFEDAL RNQPLGPVLS KAASVECISP 
       490        500        510        520        530        540 
VTPRAPDAKM LEELNAEPWY QGEMSRKEAE ALLQEDGDFL VRKSTTNPGS FVLTGMHNGQ 
       550        560        570        580        590    
AKHLLLVDPE GTVRTKDRVF DSISHLITYH LESSLPIVSA GSELCLRQPV ERKP



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O70143-1-unknown MLPRTK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    O70143-121-unknown MSATRK... 121 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt193498

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...VERKP 594 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...VERKP 594 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt153444

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)