TopFIND 4.0

O70536: Sterol O-acyltransferase 1

General Information

Protein names
- Sterol O-acyltransferase 1
- 2.3.1.26 {ECO:0000250|UniProtKB:P35610}
- Acyl-coenzyme A:cholesterol acyltransferase 1
- ACAT-1
- Cholesterol acyltransferase 1
Gene names Soat1
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID O70536

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MVGEETSLRN RLSRSAENPE QDEAQKNLLD THRNGHITMK QLIAKKRQLA AEAEELKPLF 
        70         80         90        100        110        120 
LKEVGCHFDD FVTNLIDKSA SLDNGGCALT TFSILEEMKN NHRAKDLRAP PEQGKIFISR 
       130        140        150        160        170        180 
RSLLDELFEV DHIRTIYHMF IALLIIFILS TLVVDYIDEG RLVLEFSLLA YAFGQFPIVI 
       190        200        210        220        230        240 
WTWWAMFLST LAIPYFLFQR WAHGYSKSSH PLIYSLIHGA FFLVFQLGIL GFIPTYVVLA 
       250        260        270        280        290        300 
YTLPPASRFI LILEQIRLVM KAHSYVRENV PRVLSAAKEK SSTVPVPTVN QYLYFLFAPT 
       310        320        330        340        350        360 
LIYRDSYPRT PTVRWGYVAM QFLQVFGCLF YVYYIFERLC APLFRNIKQE PFSARVLVLC 
       370        380        390        400        410        420 
VFNSILPGVL MLFLSFFAFL HCWLNAFAEM LRFGDRMFYK DWWNSTSYSN YYRTWNVVVH 
       430        440        450        460        470        480 
DWLYYYVYKD LLWFFSKRFR PAAMLAVFAL SAVVHEYALA VCLSYFYPVL FVLFMFFGMA 
       490        500        510        520        530        540 
FNFIVNDSRK RPVWNIMVRA SLFLGHGVIL CFYSQEWYAR QRCPLKNPTF LDYVRPRTWT 
   
CRYVF

Isoforms



Sequence View



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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O70536-1-Acetylation MVGEET... 1 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...CRYVF 545 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)