TopFIND 4.0

O70572: Sphingomyelin phosphodiesterase 2

General Information

Protein names
- Sphingomyelin phosphodiesterase 2
- 3.1.4.12
- Lyso-platelet-activating factor-phospholipase C
- Lyso-PAF-PLC
- Neutral sphingomyelinase
- N-SMase
- nSMase
Gene names Smpd2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID O70572

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKLNFSLRLR VFNLNCWDIP YLSKHRADRM KRLGDFLNLE NFDLALLEEV WSEQDFQYLR 
        70         80         90        100        110        120 
QRLSLTYPDA HYFRSGMIGS GLCVFSKHPI QEIFQHVYSL NGYPYMFHHG DWFCGKSVGL 
       130        140        150        160        170        180 
LVLRLSGLVL NAYVTHLHAE YSRQKDIYFA HRVAQAWELA QFIHHTSKNA DVVLLCGDLN 
       190        200        210        220        230        240 
MHPKDLGCCL LKEWTGLHDA FVETEDFKGS DDGCTMVPKN CYVSQQDLGP FPSGIRIDYV 
       250        260        270        280        290        300 
LYKAVSEFHV CCETLKTTTG CDPHSDKPFS DHEALMATLY VKHSPPQEDP CTACGPLERS 
       310        320        330        340        350        360 
DLISVLREAR TELGLGIAKA RWWAAFSGYV IVWGLSLLVL LCVLAAGEEA REVAIILCIP 
       370        380        390        400        410    
SVGLVLVAGA VYLFHKQEAK GLCRAQAEML HVLTRETETQ DRGSEPHLAY CLQQEGDRA

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O70572-1-unknown MKLNFS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...EGDRA 419 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)