TopFIND 4.0

O75363: Breast carcinoma-amplified sequence 1

General Information

Protein names
- Breast carcinoma-amplified sequence 1
- Amplified and overexpressed in breast cancer
- Novel amplified in breast cancer 1
Gene names BCAS1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O75363

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGNQMSVPQR VEDQENEPEA ETYQDNASAL NGVPVVVSTH TVQHLEEVDL GISVKTDNVA 
        70         80         90        100        110        120 
TSSPETTEIS AVADANGKNL GKEAKPEAPA AKSRFFLMLS RPVPGRTGDQ AADSSLGSVK 
       130        140        150        160        170        180 
LDVSSNKAPA NKDPSESWTL PVAAGPGQDT DKTPGHAPAQ DKVLSAARDP TLLPPETGGA 
       190        200        210        220        230        240 
GGEAPSKPKD SSFFDKFFKL DKGQEKVPGD SQQEAKRAEH QDKVDEVPGL SGQSDDVPAG 
       250        260        270        280        290        300 
KDIVDGKEKE GQELGTADCS VPGDPEGLET AKDDSQAAAI AENNNSIMSF FKTLVSPNKA 
       310        320        330        340        350        360 
ETKKDPEDTG AEKSPTTSAD LKSDKANFTS QETQGAGKNS KGCNPSGHTQ SVTTPEPAKE 
       370        380        390        400        410        420 
GTKEKSGPTS LPLGKLFWKK SVKEDSVPTG AEENVVCESP VEIIKSKEVE SALQTVDLNE 
       430        440        450        460        470        480 
GDAAPEPTEA KLKREESKPR TSLMAFLRQM SVKGDGGITH SEEINGKDSS CQTSDSTEKT 
       490        500        510        520        530        540 
ITPPEPEPTG APQKGKEGSS KDKKSAAEMN KQKSNKQEAK EPAQCTEQAT VDTNSLQNGD 
       550        560        570        580    
KLQKRPEKRQ QSLGGFFKGL GPKRMLDAQV QTDPVSIGPV GKSK

Isoforms

- Isoform 2 of Breast carcinoma-amplified sequence 1

Sequence View

        10         20         30         40         50         60 
MGNQMSVPQR VEDQENEPEA ETYQDNASAL NGVPVVVSTH TVQHLEEVDL GISVKTDNVA 
        70         80         90        100        110        120 
TSSPETTEIS AVADANGKNL GKEAKPEAPA AKSRFFLMLS RPVPGRTGDQ AADSSLGSVK 
       130        140        150        160        170        180 
LDVSSNKAPA NKDPSESWTL PVAAGPGQDT DKTPGHAPAQ DKVLSAARDP TLLPPETGGA 
       190        200        210        220        230        240 
GGEAPSKPKD SSFFDKFFKL DKGQEKVPGD SQQEAKRAEH QDKVDEVPGL SGQSDDVPAG 
       250        260        270        280        290        300 
KDIVDGKEKE GQELGTADCS VPGDPEGLET AKDDSQAAAI AENNNSIMSF FKTLVSPNKA 
       310        320        330        340        350        360 
ETKKDPEDTG AEKSPTTSAD LKSDKANFTS QETQGAGKNS KGCNPSGHTQ SVTTPEPAKE 
       370        380        390        400        410        420 
GTKEKSGPTS LPLGKLFWKK SVKEDSVPTG AEENVVCESP VEIIKSKEVE SALQTVDLNE 
       430        440        450        460        470        480 
GDAAPEPTEA KLKREESKPR TSLMAFLRQM SVKGDGGITH SEEINGKDSS CQTSDSTEKT 
       490        500        510        520        530        540 
ITPPEPEPTG APQKGKEGSS KDKKSAAEMN KQKSNKQEAK EPAQCTEQAT VDTNSLQNGD 
       550        560        570        580    
KLQKRPEKRQ QSLGGFFKGL GPKRMLDAQV QTDPVSIGPV GKSK



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Evidence Codes:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O75363-1-unknown MGNQMS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    O75363-1-unknown MGNQMS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt68295

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...VGKSK 584 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...VGKSK 584 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt93089

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)