O75385: Serine/threonine-protein kinase ULK1

General Information

Protein names	- Serine/threonine-protein kinase ULK1 - 2.7.11.1 - Autophagy-related protein 1 homolog - ATG1 - hATG1 - Unc-51-like kinase 1
Gene names	ULK1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O75385

4 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEPGRGGTET VGKFEFSRKD LIGHGAFAVV FKGRHREKHD LEVAVKCINK KNLAKSQTLL
        70         80         90        100        110        120
GKEIKILKEL KHENIVALYD FQEMANSVYL VMEYCNGGDL ADYLHAMRTL SEDTIRLFLQ
       130        140        150        160        170        180
QIAGAMRLLH SKGIIHRDLK PQNILLSNPA GRRANPNSIR VKIADFGFAR YLQSNMMAAT
       190        200        210        220        230        240
LCGSPMYMAP EVIMSQHYDG KADLWSIGTI VYQCLTGKAP FQASSPQDLR LFYEKNKTLV
       250        260        270        280        290        300
PTIPRETSAP LRQLLLALLQ RNHKDRMDFD EFFHHPFLDA SPSVRKSPPV PVPSYPSSGS
       310        320        330        340        350        360
GSSSSSSSTS HLASPPSLGE MQQLQKTLAS PADTAGFLHS SRDSGGSKDS SCDTDDFVMV
       370        380        390        400        410        420
PAQFPGDLVA EAPSAKPPPD SLMCSGSSLV ASAGLESHGR TPSPSPPCSS SPSPSGRAGP
       430        440        450        460        470        480
FSSSRCGASV PIPVPTQVQN YQRIERNLQS PTQFQTPRSS AIRRSGSTSP LGFARASPSP
       490        500        510        520        530        540
PAHAEHGGVL ARKMSLGGGR PYTPSPQVGT IPERPGWSGT PSPQGAEMRG GRSPRPGSSA
       550        560        570        580        590        600
PEHSPRTSGL GCRLHSAPNL SDLHVVRPKL PKPPTDPLGA VFSPPQASPP QPSHGLQSCR
       610        620        630        640        650        660
NLRGSPKLPD FLQRNPLPPI LGSPTKAVPS FDFPKTPSSQ NLLALLARQG VVMTPPRNRT
       670        680        690        700        710        720
LPDLSEVGPF HGQPLGPGLR PGEDPKGPFG RSFSTSRLTD LLLKAAFGTQ APDPGSTESL
       730        740        750        760        770        780
QEKPMEIAPS AGFGGSLHPG ARAGGTSSPS PVVFTVGSPP SGSTPPQGPR TRMFSAGPTG
       790        800        810        820        830        840
SASSSARHLV PGPCSEAPAP ELPAPGHGCS FADPITANLE GAVTFEAPDL PEETLMEQEH
       850        860        870        880        890        900
TEILRGLRFT LLFVQHVLEI AALKGSASEA AGGPEYQLQE SVVADQISLL SREWGFAEQL
       910        920        930        940        950        960
VLYLKVAELL SSGLQSAIDQ IRAGKLCLSS TVKQVVRRLN ELYKASVVSC QGLSLRLQRF
       970        980        990       1000       1010       1020
FLDKQRLLDR IHSITAERLI FSHAVQMVQS AALDEMFQHR EGCVPRYHKA LLLLEGLQHM
      1030       1040       1050
LSDQADIENV TKCKLCIERR LSALLTGICA

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

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Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O75385-1-unknown	MEPGRG...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O75385-84-unknown	MANSVY...	84	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000438953
O75385-107-unknown	MRTLSE...	107	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000444983
O75385-653-unknown	MTPPRN...	653	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000444298

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SQHYDG	199	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000444983
...HKDRMD	267	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000438953
...SREWGF	895	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000444298
...TGICA	1050	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)