O75563: Src kinase-associated phosphoprotein 2

General Information

Protein names	- Src kinase-associated phosphoprotein 2 - Pyk2/RAFTK-associated protein - Retinoic acid-induced protein 70 - SKAP55 homolog - SKAP-55HOM - SKAP-HOM - Src family-associated phosphoprotein 2 - Src kinase-associated phosphoprotein 55-related protein - Src-associated adapter protein with PH and SH3 domains
Gene names	SKAP2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O75563

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPNPSSTSSP YPLPEEIRNL LADVETFVAD ILKGENLSKK AKEKRESLIK KIKDVKSIYL
        70         80         90        100        110        120
QEFQDKGDAE DGEEYDDPFA GPPDTISLAS ERYDKDDEAP SDGAQFPPIA AQDLPFVLKA
       130        140        150        160        170        180
GYLEKRRKDH SFLGFEWQKR WCALSKTVFY YYGSDKDKQQ KGEFAIDGYS VRMNNTLRKD
       190        200        210        220        230        240
GKKDCCFEIS APDKRIYQFT AASPKDAEEW VQQLKFVLQD MESDIIPEDY DERGELYDDV
       250        260        270        280        290        300
DHPLPISNPL TSSQPIDDEI YEELPEEEED SAPVKVEEQR KMSQDSVHHT SGDKSTDYAN
       310        320        330        340        350
FYQGLWDCTG AFSDELSFKR GDVIYILSKE YNRYGWWVGE MKGAIGLVPK AYIMEMYDI

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O75563-1-unknown	MPNPSS...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O75563-173-unknown	MNNTLR...	173	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000443593
O75563-271-	SAPVKV...	271		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...WQKRWC	141	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000408163
	...EMYDI	359	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)