TopFIND 4.0

O75586: Mediator of RNA polymerase II transcription subunit 6

General Information

Protein names
- Mediator of RNA polymerase II transcription subunit 6
- Activator-recruited cofactor 33 kDa component
- ARC33
- Mediator complex subunit 6
- hMed6
- Renal carcinoma antigen NY-REN-28
Gene names MED6
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O75586

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAAVDIRDNL LGISWVDSSW IPILNSGSVL DYFSERSNPF YDRTCNNEVV KMQRLTLEHL 
        70         80         90        100        110        120 
NQMVGIEYIL LHAQEPILFI IRKQQRQSPA QVIPLADYYI IAGVIYQAPD LGSVINSRVL 
       130        140        150        160        170        180 
TAVHGIQSAF DEAMSYCRYH PSKGYWWHFK DHEEQDKVRP KAKRKEEPSS IFQRQRVDAL 
       190        200        210        220        230        240 
LLDLRQKFPP KFVQLKPGEK PVPVDQTKKE AEPIPETVKP EEKETTKNVQ QTVSAKGPPE 
   
KRMRLQ

Isoforms

- Isoform 2 of Mediator of RNA polymerase II transcription subunit 6 - Isoform 3 of Mediator of RNA polymerase II transcription subunit 6

Sequence View

        10         20         30         40         50         60 
MAAVDIRDNL LGISWVDSSW IPILNSGSVL DYFSERSNPF YDRTCNNEVV KMQRLTLEHL 
        70         80         90        100        110        120 
NQMVGIEYIL LHAQEPILFI IRKQQRQSPA QVIPLADYYI IAGVIYQAPD LGSVINSRVL 
       130        140        150        160        170        180 
TAVHGIQSAF DEAMSYCRYH PSKGYWWHFK DHEEQDKVRP KAKRKEEPSS IFQRQRVDAL 
       190        200        210        220        230        240 
LLDLRQKFPP KFVQLKPGEK PVPVDQTKKE AEPIPETVKP EEKETTKNVQ QTVSAKGPPE 
   
KRMRLQ         10         20         30         40         50         60 
MAAVDIRDNL LGISWVDSSW IPILNSGSVL DYFSERSNPF YDRTCNNEVV KMQRLTLEHL 
        70         80         90        100        110        120 
NQMVGIEYIL LHAQEPILFI IRKQQRQSPA QVIPLADYYI IAGVIYQAPD LGSVINSRVL 
       130        140        150        160        170        180 
TAVHGIQSAF DEAMSYCRYH PSKGYWWHFK DHEEQDKVRP KAKRKEEPSS IFQRQRVDAL 
       190        200        210        220        230        240 
LLDLRQKFPP KFVQLKPGEK PVPVDQTKKE AEPIPETVKP EEKETTKNVQ QTVSAKGPPE 
   
KRMRLQ



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O75586-1-unknown MAAVDI... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    O75586-1-unknown MAAVDI... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt80798
    O75586-1-unknown MAAVDI... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt80799

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RMRLQ 246 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...RMRLQ 246 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt76416

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)