TopFIND 4.0

O75600: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial

General Information

Protein names
- 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial
- AKB ligase
- 2.3.1.29
- Aminoacetone synthase
- Glycine acetyltransferase
Gene names GCAT
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O75600

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MWPGNAWRAA LFWVPRGRRA QSALAQLRGI LEGELEGIRG AGTWKSERVI TSRQGPHIRV 
        70         80         90        100        110        120 
DGVSGGILNF CANNYLGLSS HPEVIQAGLQ ALEEFGAGLS SVRFICGTQS IHKNLEAKIA 
       130        140        150        160        170        180 
RFHQREDAIL YPSCYDANAG LFEALLTPED AVLSDELNHA SIIDGIRLCK AHKYRYRHLD 
       190        200        210        220        230        240 
MADLEAKLQE AQKHRLRLVA TDGAFSMDGD IAPLQEICCL ASRYGALVFM DECHATGFLG 
       250        260        270        280        290        300 
PTGRGTDELL GVMDQVTIIN STLGKALGGA SGGYTTGPGP LVSLLRQRAR PYLFSNSLPP 
       310        320        330        340        350        360 
AVVGCASKAL DLLMGSNTIV QSMAAKTQRF RSKMEAAGFT ISGASHPICP VMLGDARLAS 
       370        380        390        400        410    
RMADDMLKRG IFVIGFSYPV VPKGKARIRV QISAVHSEED IDRCVEAFVE VGRLHGALP

Isoforms

- Isoform 2 of 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial

Sequence View

        10         20         30         40         50         60 
MWPGNAWRAA LFWVPRGRRA QSALAQLRGI LEGELEGIRG AGTWKSERVI TSRQGPHIRV 
        70         80         90        100        110        120 
DGVSGGILNF CANNYLGLSS HPEVIQAGLQ ALEEFGAGLS SVRFICGTQS IHKNLEAKIA 
       130        140        150        160        170        180 
RFHQREDAIL YPSCYDANAG LFEALLTPED AVLSDELNHA SIIDGIRLCK AHKYRYRHLD 
       190        200        210        220        230        240 
MADLEAKLQE AQKHRLRLVA TDGAFSMDGD IAPLQEICCL ASRYGALVFM DECHATGFLG 
       250        260        270        280        290        300 
PTGRGTDELL GVMDQVTIIN STLGKALGGA SGGYTTGPGP LVSLLRQRAR PYLFSNSLPP 
       310        320        330        340        350        360 
AVVGCASKAL DLLMGSNTIV QSMAAKTQRF RSKMEAAGFT ISGASHPICP VMLGDARLAS 
       370        380        390        400        410    
RMADDMLKRG IFVIGFSYPV VPKGKARIRV QISAVHSEED IDRCVEAFVE VGRLHGALP



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...HGALP 419 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...HGALP 419 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt74229

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)