O75689: Arf-GAP with dual PH domain-containing protein 1

General Information

Protein names	- Arf-GAP with dual PH domain-containing protein 1 - Centaurin-alpha-1 - Cnt-a1 - Putative MAPK-activating protein PM25
Gene names	ADAP1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O75689

3 N-termini

5 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Arf-GAP with dual PH domain-containing protein 1 - Isoform 3 of Arf-GAP with dual PH domain-containing protein 1

Sequence View

        10         20         30         40         50         60
MAKERRRAVL ELLQRPGNAR CADCGAPDPD WASYTLGVFI CLSCSGIHRN IPQVSKVKSV
        70         80         90        100        110        120
RLDAWEEAQV EFMASHGNDA ARARFESKVP SFYYRPTPSD CQLLREQWIR AKYERQEFIY
       130        140        150        160        170        180
PEKQEPYSAG YREGFLWKRG RDNGQFLSRK FVLTEREGAL KYFNRNDAKE PKAVMKIEHL
       190        200        210        220        230        240
NATFQPAKIG HPHGLQVTYL KDNSTRNIFI YHEDGKEIVD WFNALRAARF HYLQVAFPGA
       250        260        270        280        290        300
GDADLVPKLS RNYLKEGYME KTGPKQTEGF RKRWFTMDDR RLMYFKDPLD AFARGEVFIG
       310        320        330        340        350        360
SKESGYTVLH GFPPSTQGHH WPHGITIVTP DRKFLFACET ESDQREWVAA FQKAVDRPML
       370
PQEYAVEAHF KHKP         10         20         30         40         50         60
MAKERRRAVL ELLQRPGNAR CADCGAPDPD WASYTLGVFI CLSCSGIHRN IPQVSKVKSV
        70         80         90        100        110        120
RLDAWEEAQV EFMASHGNDA ARARFESKVP SFYYRPTPSD CQLLREQWIR AKYERQEFIY
       130        140        150        160        170        180
PEKQEPYSAG YREGFLWKRG RDNGQFLSRK FVLTEREGAL KYFNRNDAKE PKAVMKIEHL
       190        200        210        220        230        240
NATFQPAKIG HPHGLQVTYL KDNSTRNIFI YHEDGKEIVD WFNALRAARF HYLQVAFPGA
       250        260        270        280        290        300
GDADLVPKLS RNYLKEGYME KTGPKQTEGF RKRWFTMDDR RLMYFKDPLD AFARGEVFIG
       310        320        330        340        350        360
SKESGYTVLH GFPPSTQGHH WPHGITIVTP DRKFLFACET ESDQREWVAA FQKAVDRPML
       370
PQEYAVEAHF KHKP

Filter Information:

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 5 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O75689-1-unknown	MAKERR...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O75689-73-unknown	MASHGN...	73	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt66344
O75689-73-unknown	MASHGN...	73	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000407267
O75689-73-unknown	MASHGN...	73	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt98117
O75689-162-unknown	YFNRND...	162	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000409129
O75689-162-unknown	YFNRND...	162	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt132420
O75689-162-unknown	YFNRND...	162	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt132419

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PKAVMK	175	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000394973
...PKAVMK	175	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113934
...PKAVMK	175	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113933
...AGDADL	244	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000416545
...AGDADL	244	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113931
...AGDADL	244	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113930
...PKLSRN	251	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000391315
...PKLSRN	251	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113928
...PKLSRN	251	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113927
...GFRKRW	273	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000404217
...GFRKRW	273	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113925
...GFRKRW	273	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt113924
...FKHKP	374	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...FKHKP	374	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt61962
...FKHKP	374	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt61961

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)