O75791: GRB2-related adapter protein 2

General Information

Protein names	- GRB2-related adapter protein 2 - Adapter protein GRID - GRB-2-like protein - GRB2L - GRBLG - GRBX - Grf40 adapter protein - Grf-40 - Growth factor receptor-binding protein - Hematopoietic cell-associated adapter protein GrpL - P38 - Protein GADS - SH3-SH2-SH3 adapter Mona
Gene names	GRAP2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O75791

3 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEAVAKFDFT ASGEDELSFH TGDVLKILSN QEEWFKAELG SQEGYVPKNF IDIQFPKWFH
        70         80         90        100        110        120
EGLSRHQAEN LLMGKEVGFF IIRASQSSPG DFSISVRHED DVQHFKVMRD NKGNYFLWTE
       130        140        150        160        170        180
KFPSLNKLVD YYRTNSISRQ KQIFLRDRTR EDQGHRGNSL DRRSQGGPHL SGAVGEEIRP
       190        200        210        220        230        240
SMNRKLSDHP PTLPLQQHQH QPQPPQYAPA PQQLQQPPQQ RYLQHHHFHQ ERRGGSLDIN
       250        260        270        280        290        300
DGHCGTGLGS EMNAALMHRR HTDPVQLQAA GRVRWARALY DFEALEDDEL GFHSGEVVEV
       310        320        330
LDSSNPSWWT GRLHNKLGLF PANYVAPMTR

Isoforms

- Isoform 2 of GRB2-related adapter protein 2

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O75791-1-unknown	MEAVAK...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O75791-73-unknown	MGKEVG...	73	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000442195
O75791-242-unknown	GHCGTG...	242	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC1496

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SISVRH	97	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000396355
...LDINDG	241	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC1496
...APMTR	330	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CASP3_HUMAN	241	INDG.\|.GHCG	inferred from experiment	unknown	MEROPS	Graves JD	Yankee TM et al.:CD95/Fas induces cleavage of th... (C14.003)	11391000,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)