TopFIND 4.0

O75907: Diacylglycerol O-acyltransferase 1

General Information

Protein names
- Diacylglycerol O-acyltransferase 1
- 2.3.1.20 {ECO:0000269|PubMed:16214399}
- ACAT-related gene product 1
- Acyl-CoA retinol O-fatty-acyltransferase
- ARAT
- Retinol O-fatty-acyltransferase
- 2.3.1.76 {ECO:0000269|PubMed:16214399}
- Diglyceride acyltransferase
Gene names DGAT1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O75907

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGDRGSSRRR RTGSRPSSHG GGGPAAAEEE VRDAAAGPDV GAAGDAPAPA PNKDGDAGVG 
        70         80         90        100        110        120 
SGHWELRCHR LQDSLFSSDS GFSNYRGILN WCVVMLILSN ARLFLENLIK YGILVDPIQV 
       130        140        150        160        170        180 
VSLFLKDPYS WPAPCLVIAA NVFAVAAFQV EKRLAVGALT EQAGLLLHVA NLATILCFPA 
       190        200        210        220        230        240 
AVVLLVESIT PVGSLLALMA HTILFLKLFS YRDVNSWCRR ARAKAASAGK KASSAAAPHT 
       250        260        270        280        290        300 
VSYPDNLTYR DLYYFLFAPT LCYELNFPRS PRIRKRFLLR RILEMLFFTQ LQVGLIQQWM 
       310        320        330        340        350        360 
VPTIQNSMKP FKDMDYSRII ERLLKLAVPN HLIWLIFFYW LFHSCLNAVA ELMQFGDREF 
       370        380        390        400        410        420 
YRDWWNSESV TYFWQNWNIP VHKWCIRHFY KPMLRRGSSK WMARTGVFLA SAFFHEYLVS 
       430        440        450        460        470        480 
VPLRMFRLWA FTGMMAQIPL AWFVGRFFQG NYGNAAVWLS LIIGQPIAVL MYVHDYYVLN 
   
YEAPAAEA

Isoforms



Sequence View



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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PAAEA 488 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)