TopFIND 4.0

O75908: Sterol O-acyltransferase 2

General Information

Protein names
- Sterol O-acyltransferase 2
- 2.3.1.26
- Acyl-coenzyme A:cholesterol acyltransferase 2
- ACAT-2
- Cholesterol acyltransferase 2
Gene names SOAT2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O75908

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEPGGARLRL QRTEGLGGER ERQPCGDGNT ETHRAPDLVQ WTRHMEAVKA QLLEQAQGQL 
        70         80         90        100        110        120 
RELLDRAMRE AIQSYPSQDK PLPPPPPGSL SRTQEPSLGK QKVFIIRKSL LDELMEVQHF 
       130        140        150        160        170        180 
RTIYHMFIAG LCVFIISTLA IDFIDEGRLL LEFDLLIFSF GQLPLALVTW VPMFLSTLLA 
       190        200        210        220        230        240 
PYQALRLWAR GTWTQATGLG CALLAAHAVV LCALPVHVAV EHQLPPASRC VLVFEQVRFL 
       250        260        270        280        290        300 
MKSYSFLREA VPGTLRARRG EGIQAPSFSS YLYFLFCPTL IYRETYPRTP YVRWNYVAKN 
       310        320        330        340        350        360 
FAQALGCVLY ACFILGRLCV PVFANMSREP FSTRALVLSI LHATLPGIFM LLLIFFAFLH 
       370        380        390        400        410        420 
CWLNAFAEML RFGDRMFYRD WWNSTSFSNY YRTWNVVVHD WLYSYVYQDG LRLLGARARG 
       430        440        450        460        470        480 
VAMLGVFLVS AVAHEYIFCF VLGFFYPVML ILFLVIGGML NFMMHDQRTG PAWNVLMWTM 
       490        500        510        520    
LFLGQGIQVS LYCQEWYARR HCPLPQATFW GLVTPRSWSC HT

Isoforms

- Isoform 2 of Sterol O-acyltransferase 2 - Isoform 3 of Sterol O-acyltransferase 2 - Isoform 4 of Sterol O-acyltransferase 2

Sequence View

        10         20         30         40         50         60 
MEPGGARLRL QRTEGLGGER ERQPCGDGNT ETHRAPDLVQ WTRHMEAVKA QLLEQAQGQL 
        70         80         90        100        110        120 
RELLDRAMRE AIQSYPSQDK PLPPPPPGSL SRTQEPSLGK QKVFIIRKSL LDELMEVQHF 
       130        140        150        160        170        180 
RTIYHMFIAG LCVFIISTLA IDFIDEGRLL LEFDLLIFSF GQLPLALVTW VPMFLSTLLA 
       190        200        210        220        230        240 
PYQALRLWAR GTWTQATGLG CALLAAHAVV LCALPVHVAV EHQLPPASRC VLVFEQVRFL 
       250        260        270        280        290        300 
MKSYSFLREA VPGTLRARRG EGIQAPSFSS YLYFLFCPTL IYRETYPRTP YVRWNYVAKN 
       310        320        330        340        350        360 
FAQALGCVLY ACFILGRLCV PVFANMSREP FSTRALVLSI LHATLPGIFM LLLIFFAFLH 
       370        380        390        400        410        420 
CWLNAFAEML RFGDRMFYRD WWNSTSFSNY YRTWNVVVHD WLYSYVYQDG LRLLGARARG 
       430        440        450        460        470        480 
VAMLGVFLVS AVAHEYIFCF VLGFFYPVML ILFLVIGGML NFMMHDQRTG PAWNVLMWTM 
       490        500        510        520    
LFLGQGIQVS LYCQEWYARR HCPLPQATFW GLVTPRSWSC HT         10         20         30         40         50         60 
MEPGGARLRL QRTEGLGGER ERQPCGDGNT ETHRAPDLVQ WTRHMEAVKA QLLEQAQGQL 
        70         80         90        100        110        120 
RELLDRAMRE AIQSYPSQDK PLPPPPPGSL SRTQEPSLGK QKVFIIRKSL LDELMEVQHF 
       130        140        150        160        170        180 
RTIYHMFIAG LCVFIISTLA IDFIDEGRLL LEFDLLIFSF GQLPLALVTW VPMFLSTLLA 
       190        200        210        220        230        240 
PYQALRLWAR GTWTQATGLG CALLAAHAVV LCALPVHVAV EHQLPPASRC VLVFEQVRFL 
       250        260        270        280        290        300 
MKSYSFLREA VPGTLRARRG EGIQAPSFSS YLYFLFCPTL IYRETYPRTP YVRWNYVAKN 
       310        320        330        340        350        360 
FAQALGCVLY ACFILGRLCV PVFANMSREP FSTRALVLSI LHATLPGIFM LLLIFFAFLH 
       370        380        390        400        410        420 
CWLNAFAEML RFGDRMFYRD WWNSTSFSNY YRTWNVVVHD WLYSYVYQDG LRLLGARARG 
       430        440        450        460        470        480 
VAMLGVFLVS AVAHEYIFCF VLGFFYPVML ILFLVIGGML NFMMHDQRTG PAWNVLMWTM 
       490        500        510        520    
LFLGQGIQVS LYCQEWYARR HCPLPQATFW GLVTPRSWSC HT         10         20         30         40         50         60 
MEPGGARLRL QRTEGLGGER ERQPCGDGNT ETHRAPDLVQ WTRHMEAVKA QLLEQAQGQL 
        70         80         90        100        110        120 
RELLDRAMRE AIQSYPSQDK PLPPPPPGSL SRTQEPSLGK QKVFIIRKSL LDELMEVQHF 
       130        140        150        160        170        180 
RTIYHMFIAG LCVFIISTLA IDFIDEGRLL LEFDLLIFSF GQLPLALVTW VPMFLSTLLA 
       190        200        210        220        230        240 
PYQALRLWAR GTWTQATGLG CALLAAHAVV LCALPVHVAV EHQLPPASRC VLVFEQVRFL 
       250        260        270        280        290        300 
MKSYSFLREA VPGTLRARRG EGIQAPSFSS YLYFLFCPTL IYRETYPRTP YVRWNYVAKN 
       310        320        330        340        350        360 
FAQALGCVLY ACFILGRLCV PVFANMSREP FSTRALVLSI LHATLPGIFM LLLIFFAFLH 
       370        380        390        400        410        420 
CWLNAFAEML RFGDRMFYRD WWNSTSFSNY YRTWNVVVHD WLYSYVYQDG LRLLGARARG 
       430        440        450        460        470        480 
VAMLGVFLVS AVAHEYIFCF VLGFFYPVML ILFLVIGGML NFMMHDQRTG PAWNVLMWTM 
       490        500        510        520    
LFLGQGIQVS LYCQEWYARR HCPLPQATFW GLVTPRSWSC HT



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Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O75908-1-unknown MEPGGA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)