O75943: Cell cycle checkpoint protein RAD17

General Information

Protein names	- Cell cycle checkpoint protein RAD17 - hRad17 - RF-C/activator 1 homolog
Gene names	RAD17
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O75943

3 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Cell cycle checkpoint protein RAD17 - Isoform 3 of Cell cycle checkpoint protein RAD17 - Isoform 4 of Cell cycle checkpoint protein RAD17

Sequence View

        10         20         30         40         50         60
MSKTFLRPKV SSTKVTDWVD PSFDDFLECS GVSTITATSL GVNNSSHRRK NGPSTLESSR
        70         80         90        100        110        120
FPARKRGNLS SLEQIYGLEN SKEYLSENEP WVDKYKPETQ HELAVHKKKI EEVETWLKAQ
       130        140        150        160        170        180
VLERQPKQGG SILLITGPPG CGKTTTLKIL SKEHGIQVQE WINPVLPDFQ KDDFKGMFNT
       190        200        210        220        230        240
ESSFHMFPYQ SQIAVFKEFL LRATKYNKLQ MLGDDLRTDK KIILVEDLPN QFYRDSHTLH
       250        260        270        280        290        300
EVLRKYVRIG RCPLIFIISD SLSGDNNQRL LFPKEIQEEC SISNISFNPV APTIMMKFLN
       310        320        330        340        350        360
RIVTIEANKN GGKITVPDKT SLELLCQGCS GDIRSAINSL QFSSSKGENN LRPRKKGMSL
       370        380        390        400        410        420
KSDAVLSKSK RRKKPDRVFE NQEVQAIGGK DVSLFLFRAL GKILYCKRAS LTELDSPRLP
       430        440        450        460        470        480
SHLSEYERDT LLVEPEEVVE MSHMPGDLFN LYLHQNYIDF FMEIDDIVRA SEFLSFADIL
       490        500        510        520        530        540
SGDWNTRSLL REYSTSIATR GVMHSNKARG YAHCQGGGSS FRPLHKPQWF LINKKYRENC
       550        560        570        580        590        600
LAAKALFPDF CLPALCLQTQ LLPYLALLTI PMRNQAQISF IQDIGRLPLK RHFGRLKMEA
       610        620        630        640        650        660
LTDREHGMID PDSGDEAQLN GGHSAEESLG EPTQATVPET WSLPLSQNSA SELPASQPQP
       670        680
FSAQGDMEEN IIIEDYESDG T         10         20         30         40         50         60
MSKTFLRPKV SSTKVTDWVD PSFDDFLECS GVSTITATSL GVNNSSHRRK NGPSTLESSR
        70         80         90        100        110        120
FPARKRGNLS SLEQIYGLEN SKEYLSENEP WVDKYKPETQ HELAVHKKKI EEVETWLKAQ
       130        140        150        160        170        180
VLERQPKQGG SILLITGPPG CGKTTTLKIL SKEHGIQVQE WINPVLPDFQ KDDFKGMFNT
       190        200        210        220        230        240
ESSFHMFPYQ SQIAVFKEFL LRATKYNKLQ MLGDDLRTDK KIILVEDLPN QFYRDSHTLH
       250        260        270        280        290        300
EVLRKYVRIG RCPLIFIISD SLSGDNNQRL LFPKEIQEEC SISNISFNPV APTIMMKFLN
       310        320        330        340        350        360
RIVTIEANKN GGKITVPDKT SLELLCQGCS GDIRSAINSL QFSSSKGENN LRPRKKGMSL
       370        380        390        400        410        420
KSDAVLSKSK RRKKPDRVFE NQEVQAIGGK DVSLFLFRAL GKILYCKRAS LTELDSPRLP
       430        440        450        460        470        480
SHLSEYERDT LLVEPEEVVE MSHMPGDLFN LYLHQNYIDF FMEIDDIVRA SEFLSFADIL
       490        500        510        520        530        540
SGDWNTRSLL REYSTSIATR GVMHSNKARG YAHCQGGGSS FRPLHKPQWF LINKKYRENC
       550        560        570        580        590        600
LAAKALFPDF CLPALCLQTQ LLPYLALLTI PMRNQAQISF IQDIGRLPLK RHFGRLKMEA
       610        620        630        640        650        660
LTDREHGMID PDSGDEAQLN GGHSAEESLG EPTQATVPET WSLPLSQNSA SELPASQPQP
       670        680
FSAQGDMEEN IIIEDYESDG T         10         20         30         40         50         60
MSKTFLRPKV SSTKVTDWVD PSFDDFLECS GVSTITATSL GVNNSSHRRK NGPSTLESSR
        70         80         90        100        110        120
FPARKRGNLS SLEQIYGLEN SKEYLSENEP WVDKYKPETQ HELAVHKKKI EEVETWLKAQ
       130        140        150        160        170        180
VLERQPKQGG SILLITGPPG CGKTTTLKIL SKEHGIQVQE WINPVLPDFQ KDDFKGMFNT
       190        200        210        220        230        240
ESSFHMFPYQ SQIAVFKEFL LRATKYNKLQ MLGDDLRTDK KIILVEDLPN QFYRDSHTLH
       250        260        270        280        290        300
EVLRKYVRIG RCPLIFIISD SLSGDNNQRL LFPKEIQEEC SISNISFNPV APTIMMKFLN
       310        320        330        340        350        360
RIVTIEANKN GGKITVPDKT SLELLCQGCS GDIRSAINSL QFSSSKGENN LRPRKKGMSL
       370        380        390        400        410        420
KSDAVLSKSK RRKKPDRVFE NQEVQAIGGK DVSLFLFRAL GKILYCKRAS LTELDSPRLP
       430        440        450        460        470        480
SHLSEYERDT LLVEPEEVVE MSHMPGDLFN LYLHQNYIDF FMEIDDIVRA SEFLSFADIL
       490        500        510        520        530        540
SGDWNTRSLL REYSTSIATR GVMHSNKARG YAHCQGGGSS FRPLHKPQWF LINKKYRENC
       550        560        570        580        590        600
LAAKALFPDF CLPALCLQTQ LLPYLALLTI PMRNQAQISF IQDIGRLPLK RHFGRLKMEA
       610        620        630        640        650        660
LTDREHGMID PDSGDEAQLN GGHSAEESLG EPTQATVPET WSLPLSQNSA SELPASQPQP
       670        680
FSAQGDMEEN IIIEDYESDG T

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O75943-1-unknown	MSKTFL...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O75943-177-unknown	MFNTES...	177	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86882
O75943-177-unknown	MFNTES...	177	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000460357
O75943-177-unknown	MFNTES...	177	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000459448
O75943-177-unknown	MFNTES...	177	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt101482
O75943-177-unknown	MFNTES...	177	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt101483
O75943-393-unknown	SLFLFR...	393	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000460068
O75943-393-unknown	SLFLFR...	393	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt199305
O75943-393-unknown	SLFLFR...	393	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt199304
O75943-393-unknown	SLFLFR...	393	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt199306

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GMFNTE	180	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000460426
...GMFNTE	180	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155373
...GMFNTE	180	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155374
...IILVED	226	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000459448
...ESDGT	681	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...ESDGT	681	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82500
...ESDGT	681	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82501
...ESDGT	681	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82499

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)