TopFIND 4.0

O76050: E3 ubiquitin-protein ligase NEURL1

General Information

Protein names
- E3 ubiquitin-protein ligase NEURL1
- 2.3.2.27
- Neuralized-like protein 1A
- h-neu
- h-neuralized 1
- RING finger protein 67
- RING-type E3 ubiquitin transferase NEURL1 {ECO:0000305}
Gene names NEURL1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O76050

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGNNFSSIPS LPRGNPSRAP RGHPQNLKDS IGGPFPVTSH RCHHKQKHCP AVLPSGGLPA 
        70         80         90        100        110        120 
TPLLFHPHTK GSQILMDLSH KAVKRQASFC NAITFSNRPV LIYEQVRLKI TKKQCCWSGA 
       130        140        150        160        170        180 
LRLGFTSKDP SRIHPDSLPK YACPDLVSQS GFWAKALPEE FANEGNIIAF WVDKKGRVFH 
       190        200        210        220        230        240 
RINDSAVMLF FSGVRTADPL WALVDVYGLT RGVQLLDSEL VLPDCLRPRS FTALRRPSLR 
       250        260        270        280        290        300 
READDARLSV SLCDLNVPGA DGDEAAPAAG CPIPQNSLNS QHSRALPAQL DGDLRFHALR 
       310        320        330        340        350        360 
AGAHVRILDE QTVARVEHGR DERALVFTSR PVRVAETIFV KVTRSGGARP GALSFGVTTC 
       370        380        390        400        410        420 
DPGTLRPADL PFSPEALVDR KEFWAVCRVP GPLHSGDILG LVVNADGELH LSHNGAAAGM 
       430        440        450        460        470        480 
QLCVDASQPL WMLFGLHGTI TQIRILGSTI LAERGIPSLP CSPASTPTSP SALGSRLSDP 
       490        500        510        520        530        540 
LLSTCSSGPL GSSAGGTAPN SPVSLPESPV TPGLGQWSDE CTICYEHAVD TVIYTCGHMC 
       550        560        570    
LCYACGLRLK KALHACCPIC RRPIKDIIKT YRSS

Isoforms

- Isoform 2 of E3 ubiquitin-protein ligase NEURL1 - Isoform 2 of E3 ubiquitin-protein ligase NEURL1

Sequence View

        10         20         30         40         50         60 
MGNNFSSIPS LPRGNPSRAP RGHPQNLKDS IGGPFPVTSH RCHHKQKHCP AVLPSGGLPA 
        70         80         90        100        110        120 
TPLLFHPHTK GSQILMDLSH KAVKRQASFC NAITFSNRPV LIYEQVRLKI TKKQCCWSGA 
       130        140        150        160        170        180 
LRLGFTSKDP SRIHPDSLPK YACPDLVSQS GFWAKALPEE FANEGNIIAF WVDKKGRVFH 
       190        200        210        220        230        240 
RINDSAVMLF FSGVRTADPL WALVDVYGLT RGVQLLDSEL VLPDCLRPRS FTALRRPSLR 
       250        260        270        280        290        300 
READDARLSV SLCDLNVPGA DGDEAAPAAG CPIPQNSLNS QHSRALPAQL DGDLRFHALR 
       310        320        330        340        350        360 
AGAHVRILDE QTVARVEHGR DERALVFTSR PVRVAETIFV KVTRSGGARP GALSFGVTTC 
       370        380        390        400        410        420 
DPGTLRPADL PFSPEALVDR KEFWAVCRVP GPLHSGDILG LVVNADGELH LSHNGAAAGM 
       430        440        450        460        470        480 
QLCVDASQPL WMLFGLHGTI TQIRILGSTI LAERGIPSLP CSPASTPTSP SALGSRLSDP 
       490        500        510        520        530        540 
LLSTCSSGPL GSSAGGTAPN SPVSLPESPV TPGLGQWSDE CTICYEHAVD TVIYTCGHMC 
       550        560        570    
LCYACGLRLK KALHACCPIC RRPIKDIIKT YRSS         10         20         30         40         50         60 
MGNNFSSIPS LPRGNPSRAP RGHPQNLKDS IGGPFPVTSH RCHHKQKHCP AVLPSGGLPA 
        70         80         90        100        110        120 
TPLLFHPHTK GSQILMDLSH KAVKRQASFC NAITFSNRPV LIYEQVRLKI TKKQCCWSGA 
       130        140        150        160        170        180 
LRLGFTSKDP SRIHPDSLPK YACPDLVSQS GFWAKALPEE FANEGNIIAF WVDKKGRVFH 
       190        200        210        220        230        240 
RINDSAVMLF FSGVRTADPL WALVDVYGLT RGVQLLDSEL VLPDCLRPRS FTALRRPSLR 
       250        260        270        280        290        300 
READDARLSV SLCDLNVPGA DGDEAAPAAG CPIPQNSLNS QHSRALPAQL DGDLRFHALR 
       310        320        330        340        350        360 
AGAHVRILDE QTVARVEHGR DERALVFTSR PVRVAETIFV KVTRSGGARP GALSFGVTTC 
       370        380        390        400        410        420 
DPGTLRPADL PFSPEALVDR KEFWAVCRVP GPLHSGDILG LVVNADGELH LSHNGAAAGM 
       430        440        450        460        470        480 
QLCVDASQPL WMLFGLHGTI TQIRILGSTI LAERGIPSLP CSPASTPTSP SALGSRLSDP 
       490        500        510        520        530        540 
LLSTCSSGPL GSSAGGTAPN SPVSLPESPV TPGLGQWSDE CTICYEHAVD TVIYTCGHMC 
       550        560        570    
LCYACGLRLK KALHACCPIC RRPIKDIIKT YRSS



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...TYRSS 574 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...TYRSS 574 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt78261

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)