O88196: E3 ubiquitin-protein ligase TTC3

General Information

Protein names	- E3 ubiquitin-protein ligase TTC3 - 2.3.2.27 - RING-type E3 ubiquitin transferase TTC3 {ECO:0000305} - TPR repeat protein D - Mtprd
Gene names	Ttc3
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	O88196

5 N-termini

13 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of E3 ubiquitin-protein ligase TTC3 - Isoform 3 of E3 ubiquitin-protein ligase TTC3 - Isoform 4 of E3 ubiquitin-protein ligase TTC3 - Isoform 5 of E3 ubiquitin-protein ligase TTC3 - Isoform 6 of E3 ubiquitin-protein ligase TTC3

Sequence View

        10         20         30         40         50         60
MDDFAEGGLS LADDILLEDY PYEDDCICTP DFTTDDYVRV TQLYYEGVGM QYKDYAQSEK
        70         80         90        100        110        120
NLEYDICNIW CSKPLSILQD YCDAIKLYIF WPLLFQHQHS SIISRLHPCV EAIRSRAAEI
       130        140        150        160        170        180
SLKKLQHLEL MEDIVDLAKK VANDSFLIEG LLKIGYKIEN KILAMEDALN WIKYTGDVTI
       190        200        210        220        230        240
LPKLGSVDNC WPMLSIFFTE YKYHITRVVT ENCNLLEEFR RHSCMQCVKQ GELMKMRGNE
       250        260        270        280        290        300
EFSKEKFEIA VIYYTRAIEY RPENHLLYGN RALCFLRMGQ FRNALSDGKR AIVLKNTWPK
       310        320        330        340        350        360
GHYRYCDALC MLGEYDWALQ ANIKAQKLCK NDPEGIKDLI QQHVKLQKQI EDLQGRTSNK
       370        380        390        400        410        420
NPIKAFYESR AYIPRNSSAP AFRTSLNFVE TERGFRKTKY KMANGGDQNQ KVADEALKGD
       430        440        450        460        470        480
DCDCHPEFLP PPSQPPRHKG KQKSRNNESE KPSFNSEVSL QVDLKSILEK QFSKSSRAAH
       490        500        510        520        530        540
QDFANIMKML RSLIQDGYTA LLEQRCRSAA QAFTELLNGL DPQKIKQLNL AMINYVLVVY
       550        560        570        580        590        600
GLAVSLLGIG RPEELSEAEN QFKRIIEHYP NEGLDCLAYC GIGKVYLKKN RFLEALNHFE
       610        620        630        640        650        660
KAKTLISRLP GILTWPTSNV IIEESKPEKV KVMLEKFVEE CKFPPVPDAV CCYQKCRGYS
       670        680        690        700        710        720
KIQIYLTDPD FKGFIRISCC QYCKVEFHMN CWKKLKTTTF NDKIDKDFLQ GICLTPDCEG
       730        740        750        760        770        780
IISKIIIYSS GGQVKCEFEH KVIKEKVPSR PVLKQKCSSL EKLRLKEDKK LKRKIQKQEA
       790        800        810        820        830        840
KKLAQERMEE DLRESNPPKN EEPEETSDSA QRCQFLDDRI LQCIKQNADK IKSVVLNTST
       850        860        870        880        890        900
LLKELLSWKV LSTEDYTTCF SSKNFVHEAV DYVIGHLIQE KNRVKTRIFL HVLSELKELD
       910        920        930        940        950        960
PKLAPWIQRL NSFGLDAIGP FFTRYGASLK ELDFHVVTVL WDEKYGHKLG SIEGKQLDYF
       970        980        990       1000       1010       1020
FEPASAMEAR CLIWLLEEHR DKFPALHSAL DEFFDIMDSR CTVLRKQDSD EMPFGCIKVK
      1030       1040       1050       1060       1070       1080
NKGKKKKPKD SKPMLVGSGA ASVAPSSEAV TPEDHSRRNS DSAGPFAVPD HLRQDVEEFE
      1090       1100       1110       1120       1130       1140
ALYDQHSSEY VVRNKKLWDI NPKQKCSTLY DYFSQLLEEH GPLDMSDRMF SEEYEFFPEE
      1150       1160       1170       1180       1190       1200
TRQILEKAGG LKSFLLGCPR FVVIDNCIAL KKVASRLKKK RKKKNMKAKV EDISKTGEYL
      1210       1220       1230       1240       1250       1260
RVKLPLNPTA REFQPDVKSE ALSEDVKSIP GPADSSTLAA EDLKAQLDSD SSSGSASEDS
      1270       1280       1290       1300       1310       1320
RLEVASPDSP TPLCEDASPS PTPAPEEAKP TYWAQSHLVT GFCTYLPFQG FGITQRPAYI
      1330       1340       1350       1360       1370       1380
NMVPSLSQFT SIYTPLANIS SEYPMQRSMP VVPSFVASNR ADENAAAYFE SPNLNTEHDS
      1390       1400       1410       1420       1430       1440
GDHMASETQI LEDTLGVCVR SQGSAADADP ALSEPEGNSE HSGSSDSLWE ASLENVSGTT
      1450       1460       1470       1480       1490       1500
DAPAAPSVAI QVSRSMVHQE VNTEPYEPFE TQQGDLSQKE KECHLLREQL KVACENCEQI
      1510       1520       1530       1540       1550       1560
ELRSSQEIKD LEEKLQRHTE ENKISKTELD WFLQDLDREI KKWQQEKKEI QERLKALKKK
      1570       1580       1590       1600       1610       1620
IKKVINTSEM SAQKNDGFDK ECEPHPDQSL GFSSALTDEK TKAEESVRKG KELYEESHQR
      1630       1640       1650       1660       1670       1680
AVAAEVSVLE NWKEREVCKL QGVASQSEAY LKSLKLMSSD SATYPDVEYD ILSWESFLST
      1690       1700       1710       1720       1730       1740
VREEIESKKS QFEEHIKAIK NGSRLSDLSS VQLSEVSFPG CSTIHPQFLS ESSGHEDPGL
      1750       1760       1770       1780       1790       1800
VACVDSMTGA VLNDPYMDSA SGCPEEVPEL SLGSPTHQPE VTQQLELKGA SQVSPSEQSP
      1810       1820       1830       1840       1850       1860
EADEKLSGQA TRSSQSPKKP SNSIIEHLSV IFPCYTSTEL AGFIKKVRNK TKNSFSGLTI
      1870       1880       1890       1900       1910       1920
EEIVEKVTEH IVDEQKKKKP NPGKDKKTSE AHSAASVAKS SQSPPLAAAG PSARTKGQKK
      1930       1940       1950       1960       1970
DDVPAPDGNS CEICHEIFKS KNMRVLKCGH KFHKGCFKQW LKGQSTCPTC GSSDLLSEE         10         20         30         40         50         60
MDDFAEGGLS LADDILLEDY PYEDDCICTP DFTTDDYVRV TQLYYEGVGM QYKDYAQSEK
        70         80         90        100        110        120
NLEYDICNIW CSKPLSILQD YCDAIKLYIF WPLLFQHQHS SIISRLHPCV EAIRSRAAEI
       130        140        150        160        170        180
SLKKLQHLEL MEDIVDLAKK VANDSFLIEG LLKIGYKIEN KILAMEDALN WIKYTGDVTI
       190        200        210        220        230        240
LPKLGSVDNC WPMLSIFFTE YKYHITRVVT ENCNLLEEFR RHSCMQCVKQ GELMKMRGNE
       250        260        270        280        290        300
EFSKEKFEIA VIYYTRAIEY RPENHLLYGN RALCFLRMGQ FRNALSDGKR AIVLKNTWPK
       310        320        330        340        350        360
GHYRYCDALC MLGEYDWALQ ANIKAQKLCK NDPEGIKDLI QQHVKLQKQI EDLQGRTSNK
       370        380        390        400        410        420
NPIKAFYESR AYIPRNSSAP AFRTSLNFVE TERGFRKTKY KMANGGDQNQ KVADEALKGD
       430        440        450        460        470        480
DCDCHPEFLP PPSQPPRHKG KQKSRNNESE KPSFNSEVSL QVDLKSILEK QFSKSSRAAH
       490        500        510        520        530        540
QDFANIMKML RSLIQDGYTA LLEQRCRSAA QAFTELLNGL DPQKIKQLNL AMINYVLVVY
       550        560        570        580        590        600
GLAVSLLGIG RPEELSEAEN QFKRIIEHYP NEGLDCLAYC GIGKVYLKKN RFLEALNHFE
       610        620        630        640        650        660
KAKTLISRLP GILTWPTSNV IIEESKPEKV KVMLEKFVEE CKFPPVPDAV CCYQKCRGYS
       670        680        690        700        710        720
KIQIYLTDPD FKGFIRISCC QYCKVEFHMN CWKKLKTTTF NDKIDKDFLQ GICLTPDCEG
       730        740        750        760        770        780
IISKIIIYSS GGQVKCEFEH KVIKEKVPSR PVLKQKCSSL EKLRLKEDKK LKRKIQKQEA
       790        800        810        820        830        840
KKLAQERMEE DLRESNPPKN EEPEETSDSA QRCQFLDDRI LQCIKQNADK IKSVVLNTST
       850        860        870        880        890        900
LLKELLSWKV LSTEDYTTCF SSKNFVHEAV DYVIGHLIQE KNRVKTRIFL HVLSELKELD
       910        920        930        940        950        960
PKLAPWIQRL NSFGLDAIGP FFTRYGASLK ELDFHVVTVL WDEKYGHKLG SIEGKQLDYF
       970        980        990       1000       1010       1020
FEPASAMEAR CLIWLLEEHR DKFPALHSAL DEFFDIMDSR CTVLRKQDSD EMPFGCIKVK
      1030       1040       1050       1060       1070       1080
NKGKKKKPKD SKPMLVGSGA ASVAPSSEAV TPEDHSRRNS DSAGPFAVPD HLRQDVEEFE
      1090       1100       1110       1120       1130       1140
ALYDQHSSEY VVRNKKLWDI NPKQKCSTLY DYFSQLLEEH GPLDMSDRMF SEEYEFFPEE
      1150       1160       1170       1180       1190       1200
TRQILEKAGG LKSFLLGCPR FVVIDNCIAL KKVASRLKKK RKKKNMKAKV EDISKTGEYL
      1210       1220       1230       1240       1250       1260
RVKLPLNPTA REFQPDVKSE ALSEDVKSIP GPADSSTLAA EDLKAQLDSD SSSGSASEDS
      1270       1280       1290       1300       1310       1320
RLEVASPDSP TPLCEDASPS PTPAPEEAKP TYWAQSHLVT GFCTYLPFQG FGITQRPAYI
      1330       1340       1350       1360       1370       1380
NMVPSLSQFT SIYTPLANIS SEYPMQRSMP VVPSFVASNR ADENAAAYFE SPNLNTEHDS
      1390       1400       1410       1420       1430       1440
GDHMASETQI LEDTLGVCVR SQGSAADADP ALSEPEGNSE HSGSSDSLWE ASLENVSGTT
      1450       1460       1470       1480       1490       1500
DAPAAPSVAI QVSRSMVHQE VNTEPYEPFE TQQGDLSQKE KECHLLREQL KVACENCEQI
      1510       1520       1530       1540       1550       1560
ELRSSQEIKD LEEKLQRHTE ENKISKTELD WFLQDLDREI KKWQQEKKEI QERLKALKKK
      1570       1580       1590       1600       1610       1620
IKKVINTSEM SAQKNDGFDK ECEPHPDQSL GFSSALTDEK TKAEESVRKG KELYEESHQR
      1630       1640       1650       1660       1670       1680
AVAAEVSVLE NWKEREVCKL QGVASQSEAY LKSLKLMSSD SATYPDVEYD ILSWESFLST
      1690       1700       1710       1720       1730       1740
VREEIESKKS QFEEHIKAIK NGSRLSDLSS VQLSEVSFPG CSTIHPQFLS ESSGHEDPGL
      1750       1760       1770       1780       1790       1800
VACVDSMTGA VLNDPYMDSA SGCPEEVPEL SLGSPTHQPE VTQQLELKGA SQVSPSEQSP
      1810       1820       1830       1840       1850       1860
EADEKLSGQA TRSSQSPKKP SNSIIEHLSV IFPCYTSTEL AGFIKKVRNK TKNSFSGLTI
      1870       1880       1890       1900       1910       1920
EEIVEKVTEH IVDEQKKKKP NPGKDKKTSE AHSAASVAKS SQSPPLAAAG PSARTKGQKK
      1930       1940       1950       1960       1970
DDVPAPDGNS CEICHEIFKS KNMRVLKCGH KFHKGCFKQW LKGQSTCPTC GSSDLLSEE         10         20         30         40         50         60
MDDFAEGGLS LADDILLEDY PYEDDCICTP DFTTDDYVRV TQLYYEGVGM QYKDYAQSEK
        70         80         90        100        110        120
NLEYDICNIW CSKPLSILQD YCDAIKLYIF WPLLFQHQHS SIISRLHPCV EAIRSRAAEI
       130        140        150        160        170        180
SLKKLQHLEL MEDIVDLAKK VANDSFLIEG LLKIGYKIEN KILAMEDALN WIKYTGDVTI
       190        200        210        220        230        240
LPKLGSVDNC WPMLSIFFTE YKYHITRVVT ENCNLLEEFR RHSCMQCVKQ GELMKMRGNE
       250        260        270        280        290        300
EFSKEKFEIA VIYYTRAIEY RPENHLLYGN RALCFLRMGQ FRNALSDGKR AIVLKNTWPK
       310        320        330        340        350        360
GHYRYCDALC MLGEYDWALQ ANIKAQKLCK NDPEGIKDLI QQHVKLQKQI EDLQGRTSNK
       370        380        390        400        410        420
NPIKAFYESR AYIPRNSSAP AFRTSLNFVE TERGFRKTKY KMANGGDQNQ KVADEALKGD
       430        440        450        460        470        480
DCDCHPEFLP PPSQPPRHKG KQKSRNNESE KPSFNSEVSL QVDLKSILEK QFSKSSRAAH
       490        500        510        520        530        540
QDFANIMKML RSLIQDGYTA LLEQRCRSAA QAFTELLNGL DPQKIKQLNL AMINYVLVVY
       550        560        570        580        590        600
GLAVSLLGIG RPEELSEAEN QFKRIIEHYP NEGLDCLAYC GIGKVYLKKN RFLEALNHFE
       610        620        630        640        650        660
KAKTLISRLP GILTWPTSNV IIEESKPEKV KVMLEKFVEE CKFPPVPDAV CCYQKCRGYS
       670        680        690        700        710        720
KIQIYLTDPD FKGFIRISCC QYCKVEFHMN CWKKLKTTTF NDKIDKDFLQ GICLTPDCEG
       730        740        750        760        770        780
IISKIIIYSS GGQVKCEFEH KVIKEKVPSR PVLKQKCSSL EKLRLKEDKK LKRKIQKQEA
       790        800        810        820        830        840
KKLAQERMEE DLRESNPPKN EEPEETSDSA QRCQFLDDRI LQCIKQNADK IKSVVLNTST
       850        860        870        880        890        900
LLKELLSWKV LSTEDYTTCF SSKNFVHEAV DYVIGHLIQE KNRVKTRIFL HVLSELKELD
       910        920        930        940        950        960
PKLAPWIQRL NSFGLDAIGP FFTRYGASLK ELDFHVVTVL WDEKYGHKLG SIEGKQLDYF
       970        980        990       1000       1010       1020
FEPASAMEAR CLIWLLEEHR DKFPALHSAL DEFFDIMDSR CTVLRKQDSD EMPFGCIKVK
      1030       1040       1050       1060       1070       1080
NKGKKKKPKD SKPMLVGSGA ASVAPSSEAV TPEDHSRRNS DSAGPFAVPD HLRQDVEEFE
      1090       1100       1110       1120       1130       1140
ALYDQHSSEY VVRNKKLWDI NPKQKCSTLY DYFSQLLEEH GPLDMSDRMF SEEYEFFPEE
      1150       1160       1170       1180       1190       1200
TRQILEKAGG LKSFLLGCPR FVVIDNCIAL KKVASRLKKK RKKKNMKAKV EDISKTGEYL
      1210       1220       1230       1240       1250       1260
RVKLPLNPTA REFQPDVKSE ALSEDVKSIP GPADSSTLAA EDLKAQLDSD SSSGSASEDS
      1270       1280       1290       1300       1310       1320
RLEVASPDSP TPLCEDASPS PTPAPEEAKP TYWAQSHLVT GFCTYLPFQG FGITQRPAYI
      1330       1340       1350       1360       1370       1380
NMVPSLSQFT SIYTPLANIS SEYPMQRSMP VVPSFVASNR ADENAAAYFE SPNLNTEHDS
      1390       1400       1410       1420       1430       1440
GDHMASETQI LEDTLGVCVR SQGSAADADP ALSEPEGNSE HSGSSDSLWE ASLENVSGTT
      1450       1460       1470       1480       1490       1500
DAPAAPSVAI QVSRSMVHQE VNTEPYEPFE TQQGDLSQKE KECHLLREQL KVACENCEQI
      1510       1520       1530       1540       1550       1560
ELRSSQEIKD LEEKLQRHTE ENKISKTELD WFLQDLDREI KKWQQEKKEI QERLKALKKK
      1570       1580       1590       1600       1610       1620
IKKVINTSEM SAQKNDGFDK ECEPHPDQSL GFSSALTDEK TKAEESVRKG KELYEESHQR
      1630       1640       1650       1660       1670       1680
AVAAEVSVLE NWKEREVCKL QGVASQSEAY LKSLKLMSSD SATYPDVEYD ILSWESFLST
      1690       1700       1710       1720       1730       1740
VREEIESKKS QFEEHIKAIK NGSRLSDLSS VQLSEVSFPG CSTIHPQFLS ESSGHEDPGL
      1750       1760       1770       1780       1790       1800
VACVDSMTGA VLNDPYMDSA SGCPEEVPEL SLGSPTHQPE VTQQLELKGA SQVSPSEQSP
      1810       1820       1830       1840       1850       1860
EADEKLSGQA TRSSQSPKKP SNSIIEHLSV IFPCYTSTEL AGFIKKVRNK TKNSFSGLTI
      1870       1880       1890       1900       1910       1920
EEIVEKVTEH IVDEQKKKKP NPGKDKKTSE AHSAASVAKS SQSPPLAAAG PSARTKGQKK
      1930       1940       1950       1960       1970
DDVPAPDGNS CEICHEIFKS KNMRVLKCGH KFHKGCFKQW LKGQSTCPTC GSSDLLSEE         10         20         30         40         50         60
MDDFAEGGLS LADDILLEDY PYEDDCICTP DFTTDDYVRV TQLYYEGVGM QYKDYAQSEK
        70         80         90        100        110        120
NLEYDICNIW CSKPLSILQD YCDAIKLYIF WPLLFQHQHS SIISRLHPCV EAIRSRAAEI
       130        140        150        160        170        180
SLKKLQHLEL MEDIVDLAKK VANDSFLIEG LLKIGYKIEN KILAMEDALN WIKYTGDVTI
       190        200        210        220        230        240
LPKLGSVDNC WPMLSIFFTE YKYHITRVVT ENCNLLEEFR RHSCMQCVKQ GELMKMRGNE
       250        260        270        280        290        300
EFSKEKFEIA VIYYTRAIEY RPENHLLYGN RALCFLRMGQ FRNALSDGKR AIVLKNTWPK
       310        320        330        340        350        360
GHYRYCDALC MLGEYDWALQ ANIKAQKLCK NDPEGIKDLI QQHVKLQKQI EDLQGRTSNK
       370        380        390        400        410        420
NPIKAFYESR AYIPRNSSAP AFRTSLNFVE TERGFRKTKY KMANGGDQNQ KVADEALKGD
       430        440        450        460        470        480
DCDCHPEFLP PPSQPPRHKG KQKSRNNESE KPSFNSEVSL QVDLKSILEK QFSKSSRAAH
       490        500        510        520        530        540
QDFANIMKML RSLIQDGYTA LLEQRCRSAA QAFTELLNGL DPQKIKQLNL AMINYVLVVY
       550        560        570        580        590        600
GLAVSLLGIG RPEELSEAEN QFKRIIEHYP NEGLDCLAYC GIGKVYLKKN RFLEALNHFE
       610        620        630        640        650        660
KAKTLISRLP GILTWPTSNV IIEESKPEKV KVMLEKFVEE CKFPPVPDAV CCYQKCRGYS
       670        680        690        700        710        720
KIQIYLTDPD FKGFIRISCC QYCKVEFHMN CWKKLKTTTF NDKIDKDFLQ GICLTPDCEG
       730        740        750        760        770        780
IISKIIIYSS GGQVKCEFEH KVIKEKVPSR PVLKQKCSSL EKLRLKEDKK LKRKIQKQEA
       790        800        810        820        830        840
KKLAQERMEE DLRESNPPKN EEPEETSDSA QRCQFLDDRI LQCIKQNADK IKSVVLNTST
       850        860        870        880        890        900
LLKELLSWKV LSTEDYTTCF SSKNFVHEAV DYVIGHLIQE KNRVKTRIFL HVLSELKELD
       910        920        930        940        950        960
PKLAPWIQRL NSFGLDAIGP FFTRYGASLK ELDFHVVTVL WDEKYGHKLG SIEGKQLDYF
       970        980        990       1000       1010       1020
FEPASAMEAR CLIWLLEEHR DKFPALHSAL DEFFDIMDSR CTVLRKQDSD EMPFGCIKVK
      1030       1040       1050       1060       1070       1080
NKGKKKKPKD SKPMLVGSGA ASVAPSSEAV TPEDHSRRNS DSAGPFAVPD HLRQDVEEFE
      1090       1100       1110       1120       1130       1140
ALYDQHSSEY VVRNKKLWDI NPKQKCSTLY DYFSQLLEEH GPLDMSDRMF SEEYEFFPEE
      1150       1160       1170       1180       1190       1200
TRQILEKAGG LKSFLLGCPR FVVIDNCIAL KKVASRLKKK RKKKNMKAKV EDISKTGEYL
      1210       1220       1230       1240       1250       1260
RVKLPLNPTA REFQPDVKSE ALSEDVKSIP GPADSSTLAA EDLKAQLDSD SSSGSASEDS
      1270       1280       1290       1300       1310       1320
RLEVASPDSP TPLCEDASPS PTPAPEEAKP TYWAQSHLVT GFCTYLPFQG FGITQRPAYI
      1330       1340       1350       1360       1370       1380
NMVPSLSQFT SIYTPLANIS SEYPMQRSMP VVPSFVASNR ADENAAAYFE SPNLNTEHDS
      1390       1400       1410       1420       1430       1440
GDHMASETQI LEDTLGVCVR SQGSAADADP ALSEPEGNSE HSGSSDSLWE ASLENVSGTT
      1450       1460       1470       1480       1490       1500
DAPAAPSVAI QVSRSMVHQE VNTEPYEPFE TQQGDLSQKE KECHLLREQL KVACENCEQI
      1510       1520       1530       1540       1550       1560
ELRSSQEIKD LEEKLQRHTE ENKISKTELD WFLQDLDREI KKWQQEKKEI QERLKALKKK
      1570       1580       1590       1600       1610       1620
IKKVINTSEM SAQKNDGFDK ECEPHPDQSL GFSSALTDEK TKAEESVRKG KELYEESHQR
      1630       1640       1650       1660       1670       1680
AVAAEVSVLE NWKEREVCKL QGVASQSEAY LKSLKLMSSD SATYPDVEYD ILSWESFLST
      1690       1700       1710       1720       1730       1740
VREEIESKKS QFEEHIKAIK NGSRLSDLSS VQLSEVSFPG CSTIHPQFLS ESSGHEDPGL
      1750       1760       1770       1780       1790       1800
VACVDSMTGA VLNDPYMDSA SGCPEEVPEL SLGSPTHQPE VTQQLELKGA SQVSPSEQSP
      1810       1820       1830       1840       1850       1860
EADEKLSGQA TRSSQSPKKP SNSIIEHLSV IFPCYTSTEL AGFIKKVRNK TKNSFSGLTI
      1870       1880       1890       1900       1910       1920
EEIVEKVTEH IVDEQKKKKP NPGKDKKTSE AHSAASVAKS SQSPPLAAAG PSARTKGQKK
      1930       1940       1950       1960       1970
DDVPAPDGNS CEICHEIFKS KNMRVLKCGH KFHKGCFKQW LKGQSTCPTC GSSDLLSEE         10         20         30         40         50         60
MDDFAEGGLS LADDILLEDY PYEDDCICTP DFTTDDYVRV TQLYYEGVGM QYKDYAQSEK
        70         80         90        100        110        120
NLEYDICNIW CSKPLSILQD YCDAIKLYIF WPLLFQHQHS SIISRLHPCV EAIRSRAAEI
       130        140        150        160        170        180
SLKKLQHLEL MEDIVDLAKK VANDSFLIEG LLKIGYKIEN KILAMEDALN WIKYTGDVTI
       190        200        210        220        230        240
LPKLGSVDNC WPMLSIFFTE YKYHITRVVT ENCNLLEEFR RHSCMQCVKQ GELMKMRGNE
       250        260        270        280        290        300
EFSKEKFEIA VIYYTRAIEY RPENHLLYGN RALCFLRMGQ FRNALSDGKR AIVLKNTWPK
       310        320        330        340        350        360
GHYRYCDALC MLGEYDWALQ ANIKAQKLCK NDPEGIKDLI QQHVKLQKQI EDLQGRTSNK
       370        380        390        400        410        420
NPIKAFYESR AYIPRNSSAP AFRTSLNFVE TERGFRKTKY KMANGGDQNQ KVADEALKGD
       430        440        450        460        470        480
DCDCHPEFLP PPSQPPRHKG KQKSRNNESE KPSFNSEVSL QVDLKSILEK QFSKSSRAAH
       490        500        510        520        530        540
QDFANIMKML RSLIQDGYTA LLEQRCRSAA QAFTELLNGL DPQKIKQLNL AMINYVLVVY
       550        560        570        580        590        600
GLAVSLLGIG RPEELSEAEN QFKRIIEHYP NEGLDCLAYC GIGKVYLKKN RFLEALNHFE
       610        620        630        640        650        660
KAKTLISRLP GILTWPTSNV IIEESKPEKV KVMLEKFVEE CKFPPVPDAV CCYQKCRGYS
       670        680        690        700        710        720
KIQIYLTDPD FKGFIRISCC QYCKVEFHMN CWKKLKTTTF NDKIDKDFLQ GICLTPDCEG
       730        740        750        760        770        780
IISKIIIYSS GGQVKCEFEH KVIKEKVPSR PVLKQKCSSL EKLRLKEDKK LKRKIQKQEA
       790        800        810        820        830        840
KKLAQERMEE DLRESNPPKN EEPEETSDSA QRCQFLDDRI LQCIKQNADK IKSVVLNTST
       850        860        870        880        890        900
LLKELLSWKV LSTEDYTTCF SSKNFVHEAV DYVIGHLIQE KNRVKTRIFL HVLSELKELD
       910        920        930        940        950        960
PKLAPWIQRL NSFGLDAIGP FFTRYGASLK ELDFHVVTVL WDEKYGHKLG SIEGKQLDYF
       970        980        990       1000       1010       1020
FEPASAMEAR CLIWLLEEHR DKFPALHSAL DEFFDIMDSR CTVLRKQDSD EMPFGCIKVK
      1030       1040       1050       1060       1070       1080
NKGKKKKPKD SKPMLVGSGA ASVAPSSEAV TPEDHSRRNS DSAGPFAVPD HLRQDVEEFE
      1090       1100       1110       1120       1130       1140
ALYDQHSSEY VVRNKKLWDI NPKQKCSTLY DYFSQLLEEH GPLDMSDRMF SEEYEFFPEE
      1150       1160       1170       1180       1190       1200
TRQILEKAGG LKSFLLGCPR FVVIDNCIAL KKVASRLKKK RKKKNMKAKV EDISKTGEYL
      1210       1220       1230       1240       1250       1260
RVKLPLNPTA REFQPDVKSE ALSEDVKSIP GPADSSTLAA EDLKAQLDSD SSSGSASEDS
      1270       1280       1290       1300       1310       1320
RLEVASPDSP TPLCEDASPS PTPAPEEAKP TYWAQSHLVT GFCTYLPFQG FGITQRPAYI
      1330       1340       1350       1360       1370       1380
NMVPSLSQFT SIYTPLANIS SEYPMQRSMP VVPSFVASNR ADENAAAYFE SPNLNTEHDS
      1390       1400       1410       1420       1430       1440
GDHMASETQI LEDTLGVCVR SQGSAADADP ALSEPEGNSE HSGSSDSLWE ASLENVSGTT
      1450       1460       1470       1480       1490       1500
DAPAAPSVAI QVSRSMVHQE VNTEPYEPFE TQQGDLSQKE KECHLLREQL KVACENCEQI
      1510       1520       1530       1540       1550       1560
ELRSSQEIKD LEEKLQRHTE ENKISKTELD WFLQDLDREI KKWQQEKKEI QERLKALKKK
      1570       1580       1590       1600       1610       1620
IKKVINTSEM SAQKNDGFDK ECEPHPDQSL GFSSALTDEK TKAEESVRKG KELYEESHQR
      1630       1640       1650       1660       1670       1680
AVAAEVSVLE NWKEREVCKL QGVASQSEAY LKSLKLMSSD SATYPDVEYD ILSWESFLST
      1690       1700       1710       1720       1730       1740
VREEIESKKS QFEEHIKAIK NGSRLSDLSS VQLSEVSFPG CSTIHPQFLS ESSGHEDPGL
      1750       1760       1770       1780       1790       1800
VACVDSMTGA VLNDPYMDSA SGCPEEVPEL SLGSPTHQPE VTQQLELKGA SQVSPSEQSP
      1810       1820       1830       1840       1850       1860
EADEKLSGQA TRSSQSPKKP SNSIIEHLSV IFPCYTSTEL AGFIKKVRNK TKNSFSGLTI
      1870       1880       1890       1900       1910       1920
EEIVEKVTEH IVDEQKKKKP NPGKDKKTSE AHSAASVAKS SQSPPLAAAG PSARTKGQKK
      1930       1940       1950       1960       1970
DDVPAPDGNS CEICHEIFKS KNMRVLKCGH KFHKGCFKQW LKGQSTCPTC GSSDLLSEE

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 13 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O88196-1-unknown	MDDFAE...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O88196-1-unknown	MDDFAE...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt93367
O88196-1-unknown	MDDFAE...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt93368
O88196-1-unknown	MDDFAE...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt93369
O88196-1-unknown	MDDFAE...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt93371
O88196-234-unknown	MKMRGN...	234	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000122006
O88196-234-unknown	MKMRGN...	234	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt132919
O88196-234-unknown	MKMRGN...	234	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt132920
O88196-234-unknown	MKMRGN...	234	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt132918
O88196-234-unknown	MKMRGN...	234	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt132921
O88196-311-unknown	MLGEYD...	311	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000118763
O88196-311-unknown	MLGEYD...	311	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000119035
O88196-311-unknown	MLGEYD...	311	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt132908
O88196-311-unknown	MLGEYD...	311	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt132909
O88196-311-unknown	MLGEYD...	311	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt132907
O88196-311-unknown	MLGEYD...	311	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt132910
O88196-402-unknown	MANGGD...	402	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt93370
O88196-402-unknown	MANGGD...	402	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000122726
O88196-402-unknown	MANGGD...	402	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000116896
O88196-402-unknown	MANGGD...	402	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000119265
O88196-402-unknown	MANGGD...	402	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106315
O88196-402-unknown	MANGGD...	402	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106316
O88196-402-unknown	MANGGD...	402	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106314
O88196-402-unknown	MANGGD...	402	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106317
O88196-487-unknown	MKMLRS...	487	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000117369
O88196-487-unknown	MKMLRS...	487	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000123442
O88196-487-unknown	MKMLRS...	487	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt132915
O88196-487-unknown	MKMLRS...	487	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt132913
O88196-487-unknown	MKMLRS...	487	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt132914
O88196-487-unknown	MKMLRS...	487	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt132912
O88196-487-unknown	MKMLRS...	487	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt132916

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DGKRAI	291	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000122006
...DGKRAI	291	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115111
...DGKRAI	291	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115112
...DGKRAI	291	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115110
...DGKRAI	291	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115113
...PPSQPP	435	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000119035
...PPSQPP	435	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115095
...PPSQPP	435	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115093
...PPSQPP	435	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115094
...PPSQPP	435	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115092
...PPSQPP	435	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115096
...CRSAAQ	510	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000118763
...CRSAAQ	510	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115077
...CRSAAQ	510	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115075
...CRSAAQ	510	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115076
...CRSAAQ	510	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115074
...CRSAAQ	510	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115078
...NQFKRI	564	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000123442
...NQFKRI	564	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115118
...NQFKRI	564	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115116
...NQFKRI	564	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115117
...NQFKRI	564	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115115
...NQFKRI	564	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115119
...PGILTW	614	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000117369
...PGILTW	614	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115083
...PGILTW	614	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115081
...PGILTW	614	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115082
...PGILTW	614	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115080
...PGILTW	614	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115084
...EAKKLA	783	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000119265
...EAKKLA	783	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115107
...EAKKLA	783	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115105
...EAKKLA	783	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115106
...EAKKLA	783	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115104
...EAKKLA	783	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115108
...KQDSDE	1010	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000114483
...KQDSDE	1010	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115124
...KQDSDE	1010	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115122
...KQDSDE	1010	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115123
...KQDSDE	1010	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115121
...KQDSDE	1010	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115125
...VKNKGK	1023	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000122726
...VKNKGK	1023	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115065
...VKNKGK	1023	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115063
...VKNKGK	1023	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115064
...VKNKGK	1023	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115062
...VKNKGK	1023	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115066
...KVASRL	1176	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000116097
...KVASRL	1176	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115059
...KVASRL	1176	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115058
...KVASRL	1176	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115057
...KVASRL	1176	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115056
...KVASRL	1176	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115060
...VASRLK	1177	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000116896
...VASRLK	1177	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115089
...VASRLK	1177	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115088
...VASRLK	1177	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115087
...VASRLK	1177	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115086
...VASRLK	1177	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115090
...ASRLKK	1178	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000122724
...ASRLKK	1178	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115071
...ASRLKK	1178	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115070
...ASRLKK	1178	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115069
...ASRLKK	1178	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115068
...ASRLKK	1178	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115072
...RLKKKR	1180	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000123037
...RLKKKR	1180	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000121349
...RLKKKR	1180	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115101
...RLKKKR	1180	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115100
...RLKKKR	1180	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115099
...RLKKKR	1180	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115098
...RLKKKR	1180	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt115102
...LLSEE	1979	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...LLSEE	1979	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88988
...LLSEE	1979	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88987
...LLSEE	1979	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88986
...LLSEE	1979	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88985
...LLSEE	1979	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88989

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)