TopFIND 4.0

O88587: Catechol O-methyltransferase

General Information

Protein names
- Catechol O-methyltransferase
- 2.1.1.6
Gene names Comt
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID O88587

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLLAAVSLGL LLLAFLLLLR HLGWGLVAIG WFEFVQQPVH NLLMGGTKEQ RILRHVQQHA 
        70         80         90        100        110        120 
KPGDPQSVLE AIDTYCSEKE WAMNVGDAKG QIMDAVIREY RPSLVLELGA YCGYSAVRMA 
       130        140        150        160        170        180 
RLLPPGARLL TMEINPDYAA ITQQMLDFAG LQDKVSILIG ASQDLIPQLK KKYDVDTLDM 
       190        200        210        220        230        240 
VFLDHWKDRY LPDTLLLEEC GLLRKGTVLL ADNVIVPGTP DFLAYVRGSS SFECTHYSSY 
       250        260    
LEYMKVVDGL EKAVYQGPGS SPVKS

Isoforms

- Isoform Soluble of Catechol O-methyltransferase

Sequence View

        10         20         30         40         50         60 
MLLAAVSLGL LLLAFLLLLR HLGWGLVAIG WFEFVQQPVH NLLMGGTKEQ RILRHVQQHA 
        70         80         90        100        110        120 
KPGDPQSVLE AIDTYCSEKE WAMNVGDAKG QIMDAVIREY RPSLVLELGA YCGYSAVRMA 
       130        140        150        160        170        180 
RLLPPGARLL TMEINPDYAA ITQQMLDFAG LQDKVSILIG ASQDLIPQLK KKYDVDTLDM 
       190        200        210        220        230        240 
VFLDHWKDRY LPDTLLLEEC GLLRKGTVLL ADNVIVPGTP DFLAYVRGSS SFECTHYSSY 
       250        260    
LEYMKVVDGL EKAVYQGPGS SPVKS



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O88587-1-unknown MLLAAV... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    O88587-44-unknown MGGTKE... 44 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt71415

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SPVKS 265 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...SPVKS 265 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt67033

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)