TopFIND 4.0

O88643: Serine/threonine-protein kinase PAK 1 {ECO:0000305}

General Information

Protein names
- Serine/threonine-protein kinase PAK 1 {ECO:0000305}
- 2.7.11.1 {ECO:0000250|UniProtKB:Q13153}
- Alpha-PAK {ECO:0000250|UniProtKB:Q13153}
- CDC42/RAC effector kinase PAK-A
- p21-activated kinase 1 {ECO:0000250|UniProtKB:Q13153}
- PAK-1
- p65-PAK {ECO:0000250|UniProtKB:P35465}
Gene names Pak1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID O88643

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSNNGVDIQD KPPAPPMRNT STMIGAGSKD TGTLNHGSKP LPPNPEEKKK KDRFYRSILP 
        70         80         90        100        110        120 
GDKTNKKREK ERPEISLPSD FEHTIHVGFD AVTGEFTGMP EQWARLLQTS NITKSEQKKN 
       130        140        150        160        170        180 
PQAVLDVLEF YNSKKTSNSK KYMSFTDKSA EDYNSSNTLN VKTVSETPAV PPVSEDDEDD 
       190        200        210        220        230        240 
DDDATPPPVI APRPEHTKSV YTRSVIEPLP VTPTRDVATS PISPTENNTT PPDALTRNTE 
       250        260        270        280        290        300 
KQKKKPKMSD EEILEKLRSI VSVGDPKKKY TPFEKIGQGA SGTVYTAMDV ATGQEVAIKQ 
       310        320        330        340        350        360 
MNLQQQPKKE LIINEILVMR ENKNPNIVNY LDSYLVGDEL WVVMEYLAGG SLTDVVTETC 
       370        380        390        400        410        420 
MDEGQIAAVC RECLQALEFL HSNQVIHRDI KSDNILLGMD GSVKLTDFGF CAQITPEQSK 
       430        440        450        460        470        480 
RSTMVGTPYW MAPEVVTRKA YGPKVDIWSL GIMAIEMIEG EPPYLNENPL RALYLIATNG 
       490        500        510        520        530        540 
TPELQNPEKL SAIFRDFLQC CLEMDVEKRG SAKELLQHQF LKIAKPLSSL TPLMHAAKEA 
   
TKNNH

Isoforms



Sequence View



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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...TKNNH 545 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)