TopFIND 4.0

O88962: 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase

General Information

Protein names
- 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase
- 1.14.18.8 {ECO:0000250|UniProtKB:O02766}
- 7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase
- CYPVIIIB1
- Cytochrome P450 8B1
- Sterol 12-alpha-hydroxylase
Gene names Cyp8b1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID O88962

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MTLWCTVLGA LLTVVGCLCL SLLLRHRRPW EPPLDKGFVP WLGHSMAFRK NMFEFLKGMR 
        70         80         90        100        110        120 
AKHGDVFTVQ LGGQYFTFVM DPLSFGPIIK NTEKALDFQS YAKELVLKVF GYQSVDGDHR 
       130        140        150        160        170        180 
MIHLASTKHL MGQGLEELNQ AMLDSLSLVM LGPKGSSLGA SSWCEDGLFH FCYRILFKAG 
       190        200        210        220        230        240 
FLSLFGYTKD KQQDLDEADE LFRKFRRFDF LFPRFVYSLL GPREWVEVSQ LQRLFHQRLS 
       250        260        270        280        290        300 
VEQNLEKDGI SCWLGYMLQF LREQGIASSM QDKFNFMMLW ASQGNTGPTC FWVLLFLLKH 
       310        320        330        340        350        360 
QDAMKAVREE ATRVMGKARL EAKKSFTFTP SALKHTPVLD SVMEESLRLC ATPTLLRVVQ 
       370        380        390        400        410        420 
EDYVLKMASG QEYQIRRGDK VALFPYLSVH MDPDIHPEPT AFKYDRFLNP DGTRKVDFYK 
       430        440        450        460        470        480 
SGKKIHHYSM PWGSGVSKCP GRFFALSEMK TFVLLMIMYF DFKLVDPDIP VPPIDPRRWG 
       490        500    
FGTSQPSHEV RFLYRLKPVQ 

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LKPVQ 500 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)