TopFIND 4.0

O94889: Kelch-like protein 18

General Information

Protein names
- Kelch-like protein 18
Gene names KLHL18
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O94889

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MVEDGAEELE DLVHFSVSEL PSRGYGVMEE IRRQGKLCDV TLKIGDHKFS AHRIVLAASI 
        70         80         90        100        110        120 
PYFHAMFTND MMECKQDEIV MQGMDPSALE ALINFAYNGN LAIDQQNVQS LLMGASFLQL 
       130        140        150        160        170        180 
QSIKDACCTF LRERLHPKNC LGVRQFAETM MCAVLYDAAN SFIHQHFVEV SMSEEFLALP 
       190        200        210        220        230        240 
LEDVLELVSR DELNVKSEEQ VFEAALAWVR YDREQRGPYL PELLSNIRLP LCRPQFLSDR 
       250        260        270        280        290        300 
VQQDDLVRCC HKCRDLVDEA KDYHLMPERR PHLPAFRTRP RCCTSIAGLI YAVGGLNSAG 
       310        320        330        340        350        360 
DSLNVVEVFD PIANCWERCR PMTTARSRVG VAVVNGLLYA IGGYDGQLRL STVEAYNPET 
       370        380        390        400        410        420 
DTWTRVGSMN SKRSAMGTVV LDGQIYVCGG YDGNSSLSSV ETYSPETDKW TVVTSMSSNR 
       430        440        450        460        470        480 
SAAGVTVFEG RIYVSGGHDG LQIFSSVEHY NHHTATWHPA AGMLNKRCRH GAASLGSKMF 
       490        500        510        520        530        540 
VCGGYDGSGF LSIAEMYSSV ADQWCLIVPM HTRRSRVSLV ASCGRLYAVG GYDGQSNLSS 
       550        560        570    
VEMYDPETDC WTFMAPMACH EGGVGVGCIP LLTI

Isoforms

- Isoform 2 of Kelch-like protein 18

Sequence View

        10         20         30         40         50         60 
MVEDGAEELE DLVHFSVSEL PSRGYGVMEE IRRQGKLCDV TLKIGDHKFS AHRIVLAASI 
        70         80         90        100        110        120 
PYFHAMFTND MMECKQDEIV MQGMDPSALE ALINFAYNGN LAIDQQNVQS LLMGASFLQL 
       130        140        150        160        170        180 
QSIKDACCTF LRERLHPKNC LGVRQFAETM MCAVLYDAAN SFIHQHFVEV SMSEEFLALP 
       190        200        210        220        230        240 
LEDVLELVSR DELNVKSEEQ VFEAALAWVR YDREQRGPYL PELLSNIRLP LCRPQFLSDR 
       250        260        270        280        290        300 
VQQDDLVRCC HKCRDLVDEA KDYHLMPERR PHLPAFRTRP RCCTSIAGLI YAVGGLNSAG 
       310        320        330        340        350        360 
DSLNVVEVFD PIANCWERCR PMTTARSRVG VAVVNGLLYA IGGYDGQLRL STVEAYNPET 
       370        380        390        400        410        420 
DTWTRVGSMN SKRSAMGTVV LDGQIYVCGG YDGNSSLSSV ETYSPETDKW TVVTSMSSNR 
       430        440        450        460        470        480 
SAAGVTVFEG RIYVSGGHDG LQIFSSVEHY NHHTATWHPA AGMLNKRCRH GAASLGSKMF 
       490        500        510        520        530        540 
VCGGYDGSGF LSIAEMYSSV ADQWCLIVPM HTRRSRVSLV ASCGRLYAVG GYDGQSNLSS 
       550        560        570    
VEMYDPETDC WTFMAPMACH EGGVGVGCIP LLTI



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Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O94889-1-unknown MVEDGA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    O94889-66-unknown MFTNDM... 66 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt79102

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PLLTI 574 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...PLLTI 574 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt74720

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)