O94921: Cyclin-dependent kinase 14

General Information

Protein names	- Cyclin-dependent kinase 14 - 2.7.11.22 - Cell division protein kinase 14 - Serine/threonine-protein kinase PFTAIRE-1 - hPFTAIRE1
Gene names	CDK14
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O94921

6 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Cyclin-dependent kinase 14 - Isoform 3 of Cyclin-dependent kinase 14

Sequence View

        10         20         30         40         50         60
MCDLIEPQPA EKIGKMKKLR RTLSESFSRI ALKKDDTTFD EICVTKMSTR NCQGMDSVIK
        70         80         90        100        110        120
PLDTIPEDKK VRVQRTQSTF DPFEKPANQV KRVHSENNAC INFKTSSTGK ESPKVRRHSS
       130        140        150        160        170        180
PSSPTSPKFG KADSYEKLEK LGEGSYATVY KGKSKVNGKL VALKVIRLQE EEGTPFTAIR
       190        200        210        220        230        240
EASLLKGLKH ANIVLLHDII HTKETLTLVF EYVHTDLCQY MDKHPGGLHP DNVKLFLFQL
       250        260        270        280        290        300
LRGLSYIHQR YILHRDLKPQ NLLISDTGEL KLADFGLARA KSVPSHTYSN EVVTLWYRPP
       310        320        330        340        350        360
DVLLGSTEYS TCLDMWGVGC IFVEMIQGVA AFPGMKDIQD QLERIFLVLG TPNEDTWPGV
       370        380        390        400        410        420
HSLPHFKPER FTLYSSKNLR QAWNKLSYVN HAEDLASKLL QCSPKNRLSA QAALSHEYFS
       430        440        450        460
DLPPRLWELT DMSSIFTVPN VRLQPEAGES MRAFGKNNSY GKSLSNSKH         10         20         30         40         50         60
MCDLIEPQPA EKIGKMKKLR RTLSESFSRI ALKKDDTTFD EICVTKMSTR NCQGMDSVIK
        70         80         90        100        110        120
PLDTIPEDKK VRVQRTQSTF DPFEKPANQV KRVHSENNAC INFKTSSTGK ESPKVRRHSS
       130        140        150        160        170        180
PSSPTSPKFG KADSYEKLEK LGEGSYATVY KGKSKVNGKL VALKVIRLQE EEGTPFTAIR
       190        200        210        220        230        240
EASLLKGLKH ANIVLLHDII HTKETLTLVF EYVHTDLCQY MDKHPGGLHP DNVKLFLFQL
       250        260        270        280        290        300
LRGLSYIHQR YILHRDLKPQ NLLISDTGEL KLADFGLARA KSVPSHTYSN EVVTLWYRPP
       310        320        330        340        350        360
DVLLGSTEYS TCLDMWGVGC IFVEMIQGVA AFPGMKDIQD QLERIFLVLG TPNEDTWPGV
       370        380        390        400        410        420
HSLPHFKPER FTLYSSKNLR QAWNKLSYVN HAEDLASKLL QCSPKNRLSA QAALSHEYFS
       430        440        450        460
DLPPRLWELT DMSSIFTVPN VRLQPEAGES MRAFGKNNSY GKSLSNSKH

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O94921-1-unknown	MCDLIE...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O94921-47-unknown	MSTRNC...	47	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt70085
O94921-47-unknown	MSTRNC...	47	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt106906
O94921-57-unknown	SVIKPL...	57	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt165278
O94921-57-unknown	SVIKPL...	57	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt165279
O94921-57-	SVIKPL...	57		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
O94921-57-	SVIKPL...	57		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
O94921-78-unknown	STFDPF...	78	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175598
O94921-78-unknown	STFDPF...	78	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt175599
O94921-78-	STFDPF...	78		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SNSKH	469	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...SNSKH	469	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt65703
...SNSKH	469	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt65702

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)