TopFIND 4.0

O95050: Indolethylamine N-methyltransferase

General Information

Protein names
- Indolethylamine N-methyltransferase
- Indolamine N-methyltransferase
- 2.1.1.49
- 2.1.1.96
- Aromatic alkylamine N-methyltransferase
- Amine N-methyltransferase
- Arylamine N-methyltransferase
- Thioether S-methyltransferase
- TEMT
Gene names INMT
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O95050

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKGGFTGGDE YQKHFLPRDY LATYYSFDGS PSPEAEMLKF NLECLHKTFG PGGLQGDTLI 
        70         80         90        100        110        120 
DIGSGPTIYQ VLAACDSFQD ITLSDFTDRN REELEKWLKK EPGAYDWTPA VKFACELEGN 
       130        140        150        160        170        180 
SGRWEEKEEK LRAAVKRVLK CDVHLGNPLA PAVLPLADCV LTLLAMECAC CSLDAYRAAL 
       190        200        210        220        230        240 
CNLASLLKPG GHLVTTVTLR LPSYMVGKRE FSCVALEKEE VEQAVLDAGF DIEQLLHSPQ 
       250        260    
SYSVTNAANN GVCFIVARKK PGP

Isoforms

- Isoform 2 of Indolethylamine N-methyltransferase

Sequence View

        10         20         30         40         50         60 
MKGGFTGGDE YQKHFLPRDY LATYYSFDGS PSPEAEMLKF NLECLHKTFG PGGLQGDTLI 
        70         80         90        100        110        120 
DIGSGPTIYQ VLAACDSFQD ITLSDFTDRN REELEKWLKK EPGAYDWTPA VKFACELEGN 
       130        140        150        160        170        180 
SGRWEEKEEK LRAAVKRVLK CDVHLGNPLA PAVLPLADCV LTLLAMECAC CSLDAYRAAL 
       190        200        210        220        230        240 
CNLASLLKPG GHLVTTVTLR LPSYMVGKRE FSCVALEKEE VEQAVLDAGF DIEQLLHSPQ 
       250        260    
SYSVTNAANN GVCFIVARKK PGP



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O95050-1-unknown MKGGFT... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    O95050-1-unknown MKGGFT... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt77917

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...KKPGP 263 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...KKPGP 263 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt73535

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)