TopFIND 4.0

O95340: Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2

General Information

Protein names
- Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2
- PAPS synthase 2
- PAPSS 2
- Sulfurylase kinase 2
- SK 2
- SK2
- Sulfate adenylyltransferase
- 2.7.7.4
- ATP-sulfurylase
- Sulfate adenylate transferase
- SAT
- Adenylyl-sulfate kinase
- 2.7.1.25
- 3'-phosphoadenosine-5'-phosphosulfate synthase
- APS kinase
- Adenosine-5'-phosphosulfate 3'-phosphotransferase
- Adenylylsulfate 3'-phosphotransferase
Gene names PAPSS2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O95340

5

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSGIKKQKTE NQQKSTNVVY QAHHVSRNKR GQVVGTRGGF RGCTVWLTGL SGAGKTTISF 
        70         80         90        100        110        120 
ALEEYLVSHA IPCYSLDGDN VRHGLNRNLG FSPGDREENI RRIAEVAKLF ADAGLVCITS 
       130        140        150        160        170        180 
FISPFAKDRE NARKIHESAG LPFFEIFVDA PLNICESRDV KGLYKRARAG EIKGFTGIDS 
       190        200        210        220        230        240 
DYEKPETPER VLKTNLSTVS DCVHQVVELL QEQNIVPYTI IKDIHELFVP ENKLDHVRAE 
       250        260        270        280        290        300 
AETLPSLSIT KLDLQWVQVL SEGWATPLKG FMREKEYLQV MHFDTLLDDG VINMSIPIVL 
       310        320        330        340        350        360 
PVSAEDKTRL EGCSKFVLAH GGRRVAILRD AEFYEHRKEE RCSRVWGTTC TKHPHIKMVM 
       370        380        390        400        410        420 
ESGDWLVGGD LQVLEKIRWN DGLDQYRLTP LELKQKCKEM NADAVFAFQL RNPVHNGHAL 
       430        440        450        460        470        480 
LMQDTRRRLL ERGYKHPVLL LHPLGGWTKD DDVPLDWRMK QHAAVLEEGV LDPKSTIVAI 
       490        500        510        520        530        540 
FPSPMLYAGP TEVQWHCRSR MIAGANFYIV GRDPAGMPHP ETKKDLYEPT HGGKVLSMAP 
       550        560        570        580        590        600 
GLTSVEIIPF RVAAYNKAKK AMDFYDPARH NEFDFISGTR MRKLAREGEN PPDGFMAPKA 
       610    
WKVLTDYYRS LEKN

Isoforms

- Isoform B of Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2

Sequence View

        10         20         30         40         50         60 
MSGIKKQKTE NQQKSTNVVY QAHHVSRNKR GQVVGTRGGF RGCTVWLTGL SGAGKTTISF 
        70         80         90        100        110        120 
ALEEYLVSHA IPCYSLDGDN VRHGLNRNLG FSPGDREENI RRIAEVAKLF ADAGLVCITS 
       130        140        150        160        170        180 
FISPFAKDRE NARKIHESAG LPFFEIFVDA PLNICESRDV KGLYKRARAG EIKGFTGIDS 
       190        200        210        220        230        240 
DYEKPETPER VLKTNLSTVS DCVHQVVELL QEQNIVPYTI IKDIHELFVP ENKLDHVRAE 
       250        260        270        280        290        300 
AETLPSLSIT KLDLQWVQVL SEGWATPLKG FMREKEYLQV MHFDTLLDDG VINMSIPIVL 
       310        320        330        340        350        360 
PVSAEDKTRL EGCSKFVLAH GGRRVAILRD AEFYEHRKEE RCSRVWGTTC TKHPHIKMVM 
       370        380        390        400        410        420 
ESGDWLVGGD LQVLEKIRWN DGLDQYRLTP LELKQKCKEM NADAVFAFQL RNPVHNGHAL 
       430        440        450        460        470        480 
LMQDTRRRLL ERGYKHPVLL LHPLGGWTKD DDVPLDWRMK QHAAVLEEGV LDPKSTIVAI 
       490        500        510        520        530        540 
FPSPMLYAGP TEVQWHCRSR MIAGANFYIV GRDPAGMPHP ETKKDLYEPT HGGKVLSMAP 
       550        560        570        580        590        600 
GLTSVEIIPF RVAAYNKAKK AMDFYDPARH NEFDFISGTR MRKLAREGEN PPDGFMAPKA 
       610    
WKVLTDYYRS LEKN



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Protein Neighborhood

Domains & Features

5 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SLEKN 614 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...SLEKN 614 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt79873

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)