O95376: E3 ubiquitin-protein ligase ARIH2

General Information

Protein names	- E3 ubiquitin-protein ligase ARIH2 - ARI-2 - Protein ariadne-2 homolog - 2.3.2.31 {ECO:0000269\|PubMed:16118314, ECO:0000269\|PubMed:17646546, ECO:0000269\|PubMed:19340006} - RING-type E3 ubiquitin transferase ARIH2 {ECO:0000305} - Triad1 protein {ECO:0000303\|PubMed:10422847}
Gene names	ARIH2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O95376

3 N-termini

5 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSVDMNSQGS DSNEEDYDPN CEEEEEEEED DPGDIEDYYV GVASDVEQQG ADAFDPEEYQ
        70         80         90        100        110        120
FTCLTYKESE GALNEHMTSL ASVLKVSHSV AKLILVNFHW QVSEILDRYK SNSAQLLVEA
       130        140        150        160        170        180
RVQPNPSKHV PTSHPPHHCA VCMQFVRKEN LLSLACQHQF CRSCWEQHCS VLVKDGVGVG
       190        200        210        220        230        240
VSCMAQDCPL RTPEDFVFPL LPNEELREKY RRYLFRDYVE SHYQLQLCPG ADCPMVIRVQ
       250        260        270        280        290        300
EPRARRVQCN RCNEVFCFKC RQMYHAPTDC ATIRKWLTKC ADDSETANYI SAHTKDCPKC
       310        320        330        340        350        360
NICIEKNGGC NHMQCSKCKH DFCWMCLGDW KTHGSEYYEC SRYKENPDIV NQSQQAQARE
       370        380        390        400        410        420
ALKKYLFYFE RWENHNKSLQ LEAQTYQRIH EKIQERVMNN LGTWIDWQYL QNAAKLLAKC
       430        440        450        460        470        480
RYTLQYTYPY AYYMESGPRK KLFEYQQAQL EAEIENLSWK VERADSYDRG DLENQMHIAE
       490
QRRRTLLKDF HDT

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 5 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O95376-1-unknown	MSVDMN...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O95376-5-unknown	MNSQGS...	5	inferred from electronic annotation	unknown	TISdb	inferred from TISdb
O95376-33-unknown	GDIEDY...	33	inferred from electronic annotation	unknown	TISdb	inferred from TISdb

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ADAFDP	55	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000406063
...ASVLKV	85	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000404838
...SEILDR	107	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000395560
...SEILDR	107	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000397225
...HPPHHC	138	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000399788
...DFHDT	493	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)