O95573: Long-chain-fatty-acid--CoA ligase 3

General Information

Protein names	- Long-chain-fatty-acid--CoA ligase 3 - 6.2.1.3 - Long-chain acyl-CoA synthetase 3 - LACS 3
Gene names	ACSL3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O95573

2 N-termini

6 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MNNHVSSKPS TMKLKHTINP ILLYFIHFLI SLYTILTYIP FYFFSESRQE KSNRIKAKPV
        70         80         90        100        110        120
NSKPDSAYRS VNSLDGLASV LYPGCDTLDK VFTYAKNKFK NKRLLGTREV LNEEDEVQPN
       130        140        150        160        170        180
GKIFKKVILG QYNWLSYEDV FVRAFNFGNG LQMLGQKPKT NIAIFCETRA EWMIAAQACF
       190        200        210        220        230        240
MYNFQLVTLY ATLGGPAIVH ALNETEVTNI ITSKELLQTK LKDIVSLVPR LRHIITVDGK
       250        260        270        280        290        300
PPTWSEFPKG IIVHTMAAVE ALGAKASMEN QPHSKPLPSD IAVIMYTSGS TGLPKGVMIS
       310        320        330        340        350        360
HSNIIAGITG MAERIPELGE EDVYIGYLPL AHVLELSAEL VCLSHGCRIG YSSPQTLADQ
       370        380        390        400        410        420
SSKIKKGSKG DTSMLKPTLM AAVPEIMDRI YKNVMNKVSE MSSFQRNLFI LAYNYKMEQI
       430        440        450        460        470        480
SKGRNTPLCD SFVFRKVRSL LGGNIRLLLC GGAPLSATTQ RFMNICFCCP VGQGYGLTES
       490        500        510        520        530        540
AGAGTISEVW DYNTGRVGAP LVCCEIKLKN WEEGGYFNTD KPHPRGEILI GGQSVTMGYY
       550        560        570        580        590        600
KNEAKTKADF FEDENGQRWL CTGDIGEFEP DGCLKIIDRK KDLVKLQAGE YVSLGKVEAA
       610        620        630        640        650        660
LKNLPLVDNI CAYANSYHSY VIGFVVPNQK ELTELARKKG LKGTWEELCN SCEMENEVLK
       670        680        690        700        710        720
VLSEAAISAS LEKFEIPVKI RLSPEPWTPE TGLVTDAFKL KRKELKTHYQ ADIERMYGRK

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 6 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O95573-1-unknown	MNNHVS...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O95573-153-unknown	MLGQKP...	153		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000441643

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GCDTLD	88	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000416913
...VFTYAK	95	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000438342
...GSTGLP	293	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000441643
...SLLGGN	443	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000404182
...FEIPVK	678	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000385157
...MYGRK	720	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)