O95628: CCR4-NOT transcription complex subunit 4

General Information

Protein names	- CCR4-NOT transcription complex subunit 4 - 2.3.2.27 {ECO:0000269\|PubMed:11823428, ECO:0000269\|PubMed:26575292} - CCR4-associated factor 4 - E3 ubiquitin-protein ligase CNOT4 - Potential transcriptional repressor NOT4Hp - RING-type E3 ubiquitin transferase CNOT4 {ECO:0000305}
Gene names	CNOT4
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O95628

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of CCR4-NOT transcription complex subunit 4 - Isoform 3 of CCR4-NOT transcription complex subunit 4 - Isoform 4 of CCR4-NOT transcription complex subunit 4 - Isoform 5 of CCR4-NOT transcription complex subunit 4 - Isoform 6 of CCR4-NOT transcription complex subunit 4 - Isoform 7 of CCR4-NOT transcription complex subunit 4 - Isoform 8 of CCR4-NOT transcription complex subunit 4 - Isoform 9 of CCR4-NOT transcription complex subunit 4 - Isoform 10 of CCR4-NOT transcription complex subunit 4

Sequence View

        10         20         30         40         50         60
MSRSPDAKED PVECPLCMEP LEIDDINFFP CTCGYQICRF CWHRIRTDEN GLCPACRKPY
        70         80         90        100        110        120
PEDPAVYKPL SQEELQRIKN EKKQKQNERK QKISENRKHL ASVRVVQKNL VFVVGLSQRL
       130        140        150        160        170        180
ADPEVLKRPE YFGKFGKIHK VVINNSTSYA GSQGPSASAY VTYIRSEDAL RAIQCVNNVV
       190        200        210        220        230        240
VDGRTLKASL GTTKYCSYFL KNMQCPKPDC MYLHELGDEA ASFTKEEMQA GKHQEYEQKL
       250        260        270        280        290        300
LQELYKLNPN FLQLSTGSVD KNKNKVTPLQ RYDTPIDKPS DSLSIGNGDN SQQISNSDTP
       310        320        330        340        350        360
SPPPGLSKSN PVIPISSSNH SARSPFEGAV TESQSLFSDN FRHPNPIPSG LPPFPSSPQT
       370        380        390        400        410        420
SSDWPTAPEP QSLFTSETIP VSSSTDWQAA FGFGSSKQPE DDLGFDPFDV TRKALADLIE
       430        440        450        460        470        480
KELSVQDQPS LSPTSLQNSS SHTTTAKGPG SGFLHPAAAT NANSLNSTFS VLPQRFPQFQ
       490        500        510        520        530        540
QHRAVYNSFS FPGQAARYPW MAFPRNSIMH LNHTANPTSN SNFLDLNLPP QHNTGLGGIP
       550        560        570
VAGEEEVKVS TMPLSTSSHS LQQGQQPTSL HTTVA         10         20         30         40         50         60
MSRSPDAKED PVECPLCMEP LEIDDINFFP CTCGYQICRF CWHRIRTDEN GLCPACRKPY
        70         80         90        100        110        120
PEDPAVYKPL SQEELQRIKN EKKQKQNERK QKISENRKHL ASVRVVQKNL VFVVGLSQRL
       130        140        150        160        170        180
ADPEVLKRPE YFGKFGKIHK VVINNSTSYA GSQGPSASAY VTYIRSEDAL RAIQCVNNVV
       190        200        210        220        230        240
VDGRTLKASL GTTKYCSYFL KNMQCPKPDC MYLHELGDEA ASFTKEEMQA GKHQEYEQKL
       250        260        270        280        290        300
LQELYKLNPN FLQLSTGSVD KNKNKVTPLQ RYDTPIDKPS DSLSIGNGDN SQQISNSDTP
       310        320        330        340        350        360
SPPPGLSKSN PVIPISSSNH SARSPFEGAV TESQSLFSDN FRHPNPIPSG LPPFPSSPQT
       370        380        390        400        410        420
SSDWPTAPEP QSLFTSETIP VSSSTDWQAA FGFGSSKQPE DDLGFDPFDV TRKALADLIE
       430        440        450        460        470        480
KELSVQDQPS LSPTSLQNSS SHTTTAKGPG SGFLHPAAAT NANSLNSTFS VLPQRFPQFQ
       490        500        510        520        530        540
QHRAVYNSFS FPGQAARYPW MAFPRNSIMH LNHTANPTSN SNFLDLNLPP QHNTGLGGIP
       550        560        570
VAGEEEVKVS TMPLSTSSHS LQQGQQPTSL HTTVA         10         20         30         40         50         60
MSRSPDAKED PVECPLCMEP LEIDDINFFP CTCGYQICRF CWHRIRTDEN GLCPACRKPY
        70         80         90        100        110        120
PEDPAVYKPL SQEELQRIKN EKKQKQNERK QKISENRKHL ASVRVVQKNL VFVVGLSQRL
       130        140        150        160        170        180
ADPEVLKRPE YFGKFGKIHK VVINNSTSYA GSQGPSASAY VTYIRSEDAL RAIQCVNNVV
       190        200        210        220        230        240
VDGRTLKASL GTTKYCSYFL KNMQCPKPDC MYLHELGDEA ASFTKEEMQA GKHQEYEQKL
       250        260        270        280        290        300
LQELYKLNPN FLQLSTGSVD KNKNKVTPLQ RYDTPIDKPS DSLSIGNGDN SQQISNSDTP
       310        320        330        340        350        360
SPPPGLSKSN PVIPISSSNH SARSPFEGAV TESQSLFSDN FRHPNPIPSG LPPFPSSPQT
       370        380        390        400        410        420
SSDWPTAPEP QSLFTSETIP VSSSTDWQAA FGFGSSKQPE DDLGFDPFDV TRKALADLIE
       430        440        450        460        470        480
KELSVQDQPS LSPTSLQNSS SHTTTAKGPG SGFLHPAAAT NANSLNSTFS VLPQRFPQFQ
       490        500        510        520        530        540
QHRAVYNSFS FPGQAARYPW MAFPRNSIMH LNHTANPTSN SNFLDLNLPP QHNTGLGGIP
       550        560        570
VAGEEEVKVS TMPLSTSSHS LQQGQQPTSL HTTVA         10         20         30         40         50         60
MSRSPDAKED PVECPLCMEP LEIDDINFFP CTCGYQICRF CWHRIRTDEN GLCPACRKPY
        70         80         90        100        110        120
PEDPAVYKPL SQEELQRIKN EKKQKQNERK QKISENRKHL ASVRVVQKNL VFVVGLSQRL
       130        140        150        160        170        180
ADPEVLKRPE YFGKFGKIHK VVINNSTSYA GSQGPSASAY VTYIRSEDAL RAIQCVNNVV
       190        200        210        220        230        240
VDGRTLKASL GTTKYCSYFL KNMQCPKPDC MYLHELGDEA ASFTKEEMQA GKHQEYEQKL
       250        260        270        280        290        300
LQELYKLNPN FLQLSTGSVD KNKNKVTPLQ RYDTPIDKPS DSLSIGNGDN SQQISNSDTP
       310        320        330        340        350        360
SPPPGLSKSN PVIPISSSNH SARSPFEGAV TESQSLFSDN FRHPNPIPSG LPPFPSSPQT
       370        380        390        400        410        420
SSDWPTAPEP QSLFTSETIP VSSSTDWQAA FGFGSSKQPE DDLGFDPFDV TRKALADLIE
       430        440        450        460        470        480
KELSVQDQPS LSPTSLQNSS SHTTTAKGPG SGFLHPAAAT NANSLNSTFS VLPQRFPQFQ
       490        500        510        520        530        540
QHRAVYNSFS FPGQAARYPW MAFPRNSIMH LNHTANPTSN SNFLDLNLPP QHNTGLGGIP
       550        560        570
VAGEEEVKVS TMPLSTSSHS LQQGQQPTSL HTTVA         10         20         30         40         50         60
MSRSPDAKED PVECPLCMEP LEIDDINFFP CTCGYQICRF CWHRIRTDEN GLCPACRKPY
        70         80         90        100        110        120
PEDPAVYKPL SQEELQRIKN EKKQKQNERK QKISENRKHL ASVRVVQKNL VFVVGLSQRL
       130        140        150        160        170        180
ADPEVLKRPE YFGKFGKIHK VVINNSTSYA GSQGPSASAY VTYIRSEDAL RAIQCVNNVV
       190        200        210        220        230        240
VDGRTLKASL GTTKYCSYFL KNMQCPKPDC MYLHELGDEA ASFTKEEMQA GKHQEYEQKL
       250        260        270        280        290        300
LQELYKLNPN FLQLSTGSVD KNKNKVTPLQ RYDTPIDKPS DSLSIGNGDN SQQISNSDTP
       310        320        330        340        350        360
SPPPGLSKSN PVIPISSSNH SARSPFEGAV TESQSLFSDN FRHPNPIPSG LPPFPSSPQT
       370        380        390        400        410        420
SSDWPTAPEP QSLFTSETIP VSSSTDWQAA FGFGSSKQPE DDLGFDPFDV TRKALADLIE
       430        440        450        460        470        480
KELSVQDQPS LSPTSLQNSS SHTTTAKGPG SGFLHPAAAT NANSLNSTFS VLPQRFPQFQ
       490        500        510        520        530        540
QHRAVYNSFS FPGQAARYPW MAFPRNSIMH LNHTANPTSN SNFLDLNLPP QHNTGLGGIP
       550        560        570
VAGEEEVKVS TMPLSTSSHS LQQGQQPTSL HTTVA         10         20         30         40         50         60
MSRSPDAKED PVECPLCMEP LEIDDINFFP CTCGYQICRF CWHRIRTDEN GLCPACRKPY
        70         80         90        100        110        120
PEDPAVYKPL SQEELQRIKN EKKQKQNERK QKISENRKHL ASVRVVQKNL VFVVGLSQRL
       130        140        150        160        170        180
ADPEVLKRPE YFGKFGKIHK VVINNSTSYA GSQGPSASAY VTYIRSEDAL RAIQCVNNVV
       190        200        210        220        230        240
VDGRTLKASL GTTKYCSYFL KNMQCPKPDC MYLHELGDEA ASFTKEEMQA GKHQEYEQKL
       250        260        270        280        290        300
LQELYKLNPN FLQLSTGSVD KNKNKVTPLQ RYDTPIDKPS DSLSIGNGDN SQQISNSDTP
       310        320        330        340        350        360
SPPPGLSKSN PVIPISSSNH SARSPFEGAV TESQSLFSDN FRHPNPIPSG LPPFPSSPQT
       370        380        390        400        410        420
SSDWPTAPEP QSLFTSETIP VSSSTDWQAA FGFGSSKQPE DDLGFDPFDV TRKALADLIE
       430        440        450        460        470        480
KELSVQDQPS LSPTSLQNSS SHTTTAKGPG SGFLHPAAAT NANSLNSTFS VLPQRFPQFQ
       490        500        510        520        530        540
QHRAVYNSFS FPGQAARYPW MAFPRNSIMH LNHTANPTSN SNFLDLNLPP QHNTGLGGIP
       550        560        570
VAGEEEVKVS TMPLSTSSHS LQQGQQPTSL HTTVA         10         20         30         40         50         60
MSRSPDAKED PVECPLCMEP LEIDDINFFP CTCGYQICRF CWHRIRTDEN GLCPACRKPY
        70         80         90        100        110        120
PEDPAVYKPL SQEELQRIKN EKKQKQNERK QKISENRKHL ASVRVVQKNL VFVVGLSQRL
       130        140        150        160        170        180
ADPEVLKRPE YFGKFGKIHK VVINNSTSYA GSQGPSASAY VTYIRSEDAL RAIQCVNNVV
       190        200        210        220        230        240
VDGRTLKASL GTTKYCSYFL KNMQCPKPDC MYLHELGDEA ASFTKEEMQA GKHQEYEQKL
       250        260        270        280        290        300
LQELYKLNPN FLQLSTGSVD KNKNKVTPLQ RYDTPIDKPS DSLSIGNGDN SQQISNSDTP
       310        320        330        340        350        360
SPPPGLSKSN PVIPISSSNH SARSPFEGAV TESQSLFSDN FRHPNPIPSG LPPFPSSPQT
       370        380        390        400        410        420
SSDWPTAPEP QSLFTSETIP VSSSTDWQAA FGFGSSKQPE DDLGFDPFDV TRKALADLIE
       430        440        450        460        470        480
KELSVQDQPS LSPTSLQNSS SHTTTAKGPG SGFLHPAAAT NANSLNSTFS VLPQRFPQFQ
       490        500        510        520        530        540
QHRAVYNSFS FPGQAARYPW MAFPRNSIMH LNHTANPTSN SNFLDLNLPP QHNTGLGGIP
       550        560        570
VAGEEEVKVS TMPLSTSSHS LQQGQQPTSL HTTVA         10         20         30         40         50         60
MSRSPDAKED PVECPLCMEP LEIDDINFFP CTCGYQICRF CWHRIRTDEN GLCPACRKPY
        70         80         90        100        110        120
PEDPAVYKPL SQEELQRIKN EKKQKQNERK QKISENRKHL ASVRVVQKNL VFVVGLSQRL
       130        140        150        160        170        180
ADPEVLKRPE YFGKFGKIHK VVINNSTSYA GSQGPSASAY VTYIRSEDAL RAIQCVNNVV
       190        200        210        220        230        240
VDGRTLKASL GTTKYCSYFL KNMQCPKPDC MYLHELGDEA ASFTKEEMQA GKHQEYEQKL
       250        260        270        280        290        300
LQELYKLNPN FLQLSTGSVD KNKNKVTPLQ RYDTPIDKPS DSLSIGNGDN SQQISNSDTP
       310        320        330        340        350        360
SPPPGLSKSN PVIPISSSNH SARSPFEGAV TESQSLFSDN FRHPNPIPSG LPPFPSSPQT
       370        380        390        400        410        420
SSDWPTAPEP QSLFTSETIP VSSSTDWQAA FGFGSSKQPE DDLGFDPFDV TRKALADLIE
       430        440        450        460        470        480
KELSVQDQPS LSPTSLQNSS SHTTTAKGPG SGFLHPAAAT NANSLNSTFS VLPQRFPQFQ
       490        500        510        520        530        540
QHRAVYNSFS FPGQAARYPW MAFPRNSIMH LNHTANPTSN SNFLDLNLPP QHNTGLGGIP
       550        560        570
VAGEEEVKVS TMPLSTSSHS LQQGQQPTSL HTTVA         10         20         30         40         50         60
MSRSPDAKED PVECPLCMEP LEIDDINFFP CTCGYQICRF CWHRIRTDEN GLCPACRKPY
        70         80         90        100        110        120
PEDPAVYKPL SQEELQRIKN EKKQKQNERK QKISENRKHL ASVRVVQKNL VFVVGLSQRL
       130        140        150        160        170        180
ADPEVLKRPE YFGKFGKIHK VVINNSTSYA GSQGPSASAY VTYIRSEDAL RAIQCVNNVV
       190        200        210        220        230        240
VDGRTLKASL GTTKYCSYFL KNMQCPKPDC MYLHELGDEA ASFTKEEMQA GKHQEYEQKL
       250        260        270        280        290        300
LQELYKLNPN FLQLSTGSVD KNKNKVTPLQ RYDTPIDKPS DSLSIGNGDN SQQISNSDTP
       310        320        330        340        350        360
SPPPGLSKSN PVIPISSSNH SARSPFEGAV TESQSLFSDN FRHPNPIPSG LPPFPSSPQT
       370        380        390        400        410        420
SSDWPTAPEP QSLFTSETIP VSSSTDWQAA FGFGSSKQPE DDLGFDPFDV TRKALADLIE
       430        440        450        460        470        480
KELSVQDQPS LSPTSLQNSS SHTTTAKGPG SGFLHPAAAT NANSLNSTFS VLPQRFPQFQ
       490        500        510        520        530        540
QHRAVYNSFS FPGQAARYPW MAFPRNSIMH LNHTANPTSN SNFLDLNLPP QHNTGLGGIP
       550        560        570
VAGEEEVKVS TMPLSTSSHS LQQGQQPTSL HTTVA

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O95628-1-unknown	MSRSPD...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O95628-1-unknown	MSRSPD...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt71179
O95628-1-unknown	MSRSPD...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt71181
O95628-1-unknown	MSRSPD...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt71182
O95628-1-unknown	MSRSPD...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt71183
O95628-1-unknown	MSRSPD...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt71184
O95628-1-unknown	MSRSPD...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt71185
O95628-1-unknown	MSRSPD...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt71186
O95628-18-unknown	MEPLEI...	18	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt71180
O95628-18-unknown	MEPLEI...	18	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt96461
O95628-18-unknown	MEPLEI...	18	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt96462
O95628-18-unknown	MEPLEI...	18	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt96463
O95628-18-unknown	MEPLEI...	18	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt96464
O95628-18-unknown	MEPLEI...	18	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt96465
O95628-18-unknown	MEPLEI...	18	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt96466
O95628-18-unknown	MEPLEI...	18	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt96467

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...HTTVA	575	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...HTTVA	575	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt66798
...HTTVA	575	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt66797

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)