TopFIND 4.0

O95639: Cleavage and polyadenylation specificity factor subunit 4

General Information

Protein names
- Cleavage and polyadenylation specificity factor subunit 4
- Cleavage and polyadenylation specificity factor 30 kDa subunit
- CPSF 30 kDa subunit
- NS1 effector domain-binding protein 1
- Neb-1
- No arches homolog
Gene names CPSF4
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O95639

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MQEIIASVDH IKFDLEIAVE QQLGAQPLPF PGMDKSGAAV CEFFLKAACG KGGMCPFRHI 
        70         80         90        100        110        120 
SGEKTVVCKH WLRGLCKKGD QCEFLHEYDM TKMPECYFYS KFGECSNKEC PFLHIDPESK 
       130        140        150        160        170        180 
IKDCPWYDRG FCKHGPLCRH RHTRRVICVN YLVGFCPEGP SCKFMHPRFE LPMGTTEQPP 
       190        200        210        220        230        240 
LPQQTQPPAK QSNNPPLQRS SSLIQLTSQN SSPNQQRTPQ VIGVMQSQNS SAGNRGPRPL 
       250        260    
EQVTCYKCGE KGHYANRCTK GHLAFLSGQ

Isoforms

- Isoform 2 of Cleavage and polyadenylation specificity factor subunit 4 - Isoform 3 of Cleavage and polyadenylation specificity factor subunit 4

Sequence View

        10         20         30         40         50         60 
MQEIIASVDH IKFDLEIAVE QQLGAQPLPF PGMDKSGAAV CEFFLKAACG KGGMCPFRHI 
        70         80         90        100        110        120 
SGEKTVVCKH WLRGLCKKGD QCEFLHEYDM TKMPECYFYS KFGECSNKEC PFLHIDPESK 
       130        140        150        160        170        180 
IKDCPWYDRG FCKHGPLCRH RHTRRVICVN YLVGFCPEGP SCKFMHPRFE LPMGTTEQPP 
       190        200        210        220        230        240 
LPQQTQPPAK QSNNPPLQRS SSLIQLTSQN SSPNQQRTPQ VIGVMQSQNS SAGNRGPRPL 
       250        260    
EQVTCYKCGE KGHYANRCTK GHLAFLSGQ         10         20         30         40         50         60 
MQEIIASVDH IKFDLEIAVE QQLGAQPLPF PGMDKSGAAV CEFFLKAACG KGGMCPFRHI 
        70         80         90        100        110        120 
SGEKTVVCKH WLRGLCKKGD QCEFLHEYDM TKMPECYFYS KFGECSNKEC PFLHIDPESK 
       130        140        150        160        170        180 
IKDCPWYDRG FCKHGPLCRH RHTRRVICVN YLVGFCPEGP SCKFMHPRFE LPMGTTEQPP 
       190        200        210        220        230        240 
LPQQTQPPAK QSNNPPLQRS SSLIQLTSQN SSPNQQRTPQ VIGVMQSQNS SAGNRGPRPL 
       250        260    
EQVTCYKCGE KGHYANRCTK GHLAFLSGQ



Filter Information:


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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O95639-1-unknown MQEIIA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    O95639-1-unknown MQEIIA... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt71571
    O95639-1-unknown MQEIIA... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt71572

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)