O95677: Eyes absent homolog 4

General Information

Protein names	- Eyes absent homolog 4 - 3.1.3.48 {ECO:0000250\|UniProtKB:Q99502}
Gene names	EYA4
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O95677

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Eyes absent homolog 4 - Isoform 3 of Eyes absent homolog 4 - Isoform 4 of Eyes absent homolog 4 - Isoform 5 of Eyes absent homolog 4

Sequence View

        10         20         30         40         50         60
MEDSQDLNEQ SVKKTCTESD VSQSQNSRSM EMQDLASPHT LVGGGDTPGS SKLEKSNLSS
        70         80         90        100        110        120
TSVTTNGTGG ENMTVLNTAD WLLSCNTPSS ATMSLLAVKT EPLNSSETTA TTGDGALDTF
       130        140        150        160        170        180
TGSVITSSGY SPRSAHQYSP QLYPSKPYPH ILSTPAAQTM SAYAGQTQYS GMQQPAVYTA
       190        200        210        220        230        240
YSQTGQPYSL PTYDLGVMLP AIKTESGLSQ TQSPLQSGCL SYSPGFSTPQ PGQTPYSYQM
       250        260        270        280        290        300
PGSSFAPSST IYANNSVSNS TNFSGSQQDY PSYTAFGQNQ YAQYYSASTY GAYMTSNNTA
       310        320        330        340        350        360
DGTPSSTSTY QLQESLPGLT NQPGEFDTMQ SPSTPIKDLD ERTCRSSGSK SRGRGRKNNP
       370        380        390        400        410        420
SPPPDSDLER VFVWDLDETI IVFHSLLTGS YAQKYGKDPP MAVTLGLRME EMIFNLADTH
       430        440        450        460        470        480
LFFNDLEECD QVHIDDVSSD DNGQDLSTYS FATDGFHAAA SSANLCLPTG VRGGVDWMRK
       490        500        510        520        530        540
LAFRYRRVKE LYNTYKNNVG GLLGPAKRDA WLQLRAEIEG LTDSWLTNAL KSLSIISTRS
       550        560        570        580        590        600
NCINVLVTTT QLIPALAKVL LYSLGGAFPI ENIYSATKIG KESCFERIMQ RFGRKVVYVV
       610        620        630
IGDGVEEEQA AKKHNMPFWR ISSHSDLLAL HQALELEYL         10         20         30         40         50         60
MEDSQDLNEQ SVKKTCTESD VSQSQNSRSM EMQDLASPHT LVGGGDTPGS SKLEKSNLSS
        70         80         90        100        110        120
TSVTTNGTGG ENMTVLNTAD WLLSCNTPSS ATMSLLAVKT EPLNSSETTA TTGDGALDTF
       130        140        150        160        170        180
TGSVITSSGY SPRSAHQYSP QLYPSKPYPH ILSTPAAQTM SAYAGQTQYS GMQQPAVYTA
       190        200        210        220        230        240
YSQTGQPYSL PTYDLGVMLP AIKTESGLSQ TQSPLQSGCL SYSPGFSTPQ PGQTPYSYQM
       250        260        270        280        290        300
PGSSFAPSST IYANNSVSNS TNFSGSQQDY PSYTAFGQNQ YAQYYSASTY GAYMTSNNTA
       310        320        330        340        350        360
DGTPSSTSTY QLQESLPGLT NQPGEFDTMQ SPSTPIKDLD ERTCRSSGSK SRGRGRKNNP
       370        380        390        400        410        420
SPPPDSDLER VFVWDLDETI IVFHSLLTGS YAQKYGKDPP MAVTLGLRME EMIFNLADTH
       430        440        450        460        470        480
LFFNDLEECD QVHIDDVSSD DNGQDLSTYS FATDGFHAAA SSANLCLPTG VRGGVDWMRK
       490        500        510        520        530        540
LAFRYRRVKE LYNTYKNNVG GLLGPAKRDA WLQLRAEIEG LTDSWLTNAL KSLSIISTRS
       550        560        570        580        590        600
NCINVLVTTT QLIPALAKVL LYSLGGAFPI ENIYSATKIG KESCFERIMQ RFGRKVVYVV
       610        620        630
IGDGVEEEQA AKKHNMPFWR ISSHSDLLAL HQALELEYL         10         20         30         40         50         60
MEDSQDLNEQ SVKKTCTESD VSQSQNSRSM EMQDLASPHT LVGGGDTPGS SKLEKSNLSS
        70         80         90        100        110        120
TSVTTNGTGG ENMTVLNTAD WLLSCNTPSS ATMSLLAVKT EPLNSSETTA TTGDGALDTF
       130        140        150        160        170        180
TGSVITSSGY SPRSAHQYSP QLYPSKPYPH ILSTPAAQTM SAYAGQTQYS GMQQPAVYTA
       190        200        210        220        230        240
YSQTGQPYSL PTYDLGVMLP AIKTESGLSQ TQSPLQSGCL SYSPGFSTPQ PGQTPYSYQM
       250        260        270        280        290        300
PGSSFAPSST IYANNSVSNS TNFSGSQQDY PSYTAFGQNQ YAQYYSASTY GAYMTSNNTA
       310        320        330        340        350        360
DGTPSSTSTY QLQESLPGLT NQPGEFDTMQ SPSTPIKDLD ERTCRSSGSK SRGRGRKNNP
       370        380        390        400        410        420
SPPPDSDLER VFVWDLDETI IVFHSLLTGS YAQKYGKDPP MAVTLGLRME EMIFNLADTH
       430        440        450        460        470        480
LFFNDLEECD QVHIDDVSSD DNGQDLSTYS FATDGFHAAA SSANLCLPTG VRGGVDWMRK
       490        500        510        520        530        540
LAFRYRRVKE LYNTYKNNVG GLLGPAKRDA WLQLRAEIEG LTDSWLTNAL KSLSIISTRS
       550        560        570        580        590        600
NCINVLVTTT QLIPALAKVL LYSLGGAFPI ENIYSATKIG KESCFERIMQ RFGRKVVYVV
       610        620        630
IGDGVEEEQA AKKHNMPFWR ISSHSDLLAL HQALELEYL         10         20         30         40         50         60
MEDSQDLNEQ SVKKTCTESD VSQSQNSRSM EMQDLASPHT LVGGGDTPGS SKLEKSNLSS
        70         80         90        100        110        120
TSVTTNGTGG ENMTVLNTAD WLLSCNTPSS ATMSLLAVKT EPLNSSETTA TTGDGALDTF
       130        140        150        160        170        180
TGSVITSSGY SPRSAHQYSP QLYPSKPYPH ILSTPAAQTM SAYAGQTQYS GMQQPAVYTA
       190        200        210        220        230        240
YSQTGQPYSL PTYDLGVMLP AIKTESGLSQ TQSPLQSGCL SYSPGFSTPQ PGQTPYSYQM
       250        260        270        280        290        300
PGSSFAPSST IYANNSVSNS TNFSGSQQDY PSYTAFGQNQ YAQYYSASTY GAYMTSNNTA
       310        320        330        340        350        360
DGTPSSTSTY QLQESLPGLT NQPGEFDTMQ SPSTPIKDLD ERTCRSSGSK SRGRGRKNNP
       370        380        390        400        410        420
SPPPDSDLER VFVWDLDETI IVFHSLLTGS YAQKYGKDPP MAVTLGLRME EMIFNLADTH
       430        440        450        460        470        480
LFFNDLEECD QVHIDDVSSD DNGQDLSTYS FATDGFHAAA SSANLCLPTG VRGGVDWMRK
       490        500        510        520        530        540
LAFRYRRVKE LYNTYKNNVG GLLGPAKRDA WLQLRAEIEG LTDSWLTNAL KSLSIISTRS
       550        560        570        580        590        600
NCINVLVTTT QLIPALAKVL LYSLGGAFPI ENIYSATKIG KESCFERIMQ RFGRKVVYVV
       610        620        630
IGDGVEEEQA AKKHNMPFWR ISSHSDLLAL HQALELEYL

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
O95677-1-Acetylation	MEDSQD...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O95677-1-Acetylation	MEDSQD...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt100730
O95677-1-Acetylation	MEDSQD...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt100731
O95677-1-Acetylation	MEDSQD...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt100732
O95677-1-Acetylation	MEDSQD...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt100733
O95677-1-unknown	MEDSQD...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt74348
O95677-1-unknown	MEDSQD...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt74349
O95677-1-unknown	MEDSQD...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt74350
O95677-1-unknown	MEDSQD...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt74351

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ELEYL	639	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...ELEYL	639	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt69969
...ELEYL	639	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt69966
...ELEYL	639	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt69968

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

TopFIND

O95677: Eyes absent homolog 4

General Information

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

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Physiological Relevance:

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Methodology:

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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates