O95741: Copine-6 {ECO:0000305}

General Information

Protein names	- Copine-6 {ECO:0000305} - Copine VI {ECO:0000250\|UniProtKB:Q99829, ECO:0000312\|HGNC:HGNC:2319} - Neuronal-copine {ECO:0000303\|PubMed:9645480} - N-copine {ECO:0000303\|PubMed:9645480}
Gene names	CPNE6
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O95741

2 N-termini

10 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSDPEMGWVP EPPTMTLGAS RVELRVSCHG LLDRDTLTKP HPCVLLKLYS DEQWVEVERT
        70         80         90        100        110        120
EVLRSCSSPV FSRVLALEYF FEEKQPLQFH VFDAEDGATS PRNDTFLGST ECTLGQIVSQ
       130        140        150        160        170        180
TKVTKPLLLK NGKTAGKSTI TIVAEEVSGT NDYVQLTFRA YKLDNKDLFS KSDPFMEIYK
       190        200        210        220        230        240
TNEDQSDQLV WRTEVVKNNL NPSWEPFRLS LHSLCSCDVH RPLKFLVYDY DSSGKHDFIG
       250        260        270        280        290        300
EFTSTFQEMQ EGTANPGQEM QWDCINPKYR DKKKNYKSSG TVVLAQCTVE KVHTFLDYIM
       310        320        330        340        350        360
GGCQISFTVA IDFTASNGDP RSSQSLHCLS PRQPNHYLQA LRAVGGICQD YDSDKRFPAF
       370        380        390        400        410        420
GFGARIPPNF EVSHDFAINF DPENPECEEI SGVIASYRRC LPQIQLYGPT NVAPIINRVA
       430        440        450        460        470        480
EPAQREQSTG QATKYSVLLV LTDGVVSDMA ETRTAIVRAS RLPMSIIIVG VGNADFSDMR
       490        500        510        520        530        540
LLDGDDGPLR CPRGVPAARD IVQFVPFRDF KDAAPSALAK CVLAEVPRQV VEYYASQGIS
       550
PGAPRPCTLA TTPSPSP

Isoforms

- Isoform 2 of Copine-6

Sequence View

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Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 10 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O95741-1-unknown	MSDPEM...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O95741-1-unknown	MSDPEM...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt102814
O95741-176-unknown	MEIYKT...	176	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000453326
O95741-176-unknown	MEIYKT...	176	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000452653
O95741-176-unknown	MEIYKT...	176	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt131950

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LYSDEQ	52	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454166
...LYSDEQ	52	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt112807
...PRNDTF	105	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000453483
...PRNDTF	105	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt112803
...LLLKNG	131	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454093
...LLLKNG	131	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt112801
...KSTITI	141	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454192
...KSTITI	141	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt112799
...AEEVSG	148	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000452826
...AEEVSG	148	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt112813
...EEVSGT	149	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454075
...EEVSGT	149	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt112805
...KNNLNP	201	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000453326
...KNNLNP	201	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt112811
...PLKFLV	226	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000453352
...PLKFLV	226	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt112809
...TVVLAQ	285	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000452653
...TVVLAQ	285	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt112815
...PSPSP	557	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...PSPSP	557	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt67181

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)