O95866: Megakaryocyte and platelet inhibitory receptor G6b {ECO:0000312|HGNC:HGNC:13937}

General Information

Protein names	- Megakaryocyte and platelet inhibitory receptor G6b {ECO:0000312\|HGNC:HGNC:13937} - Protein G6b {ECO:0000305}
Gene names	G6B
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O95866

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform A of Protein G6b - Isoform C of Protein G6b - Isoform D of Protein G6b - Isoform E of Protein G6b - Isoform F of Protein G6b - Isoform G of Protein G6b - Isoform A of Megakaryocyte and platelet inhibitory receptor G6b - Isoform C of Megakaryocyte and platelet inhibitory receptor G6b - Isoform D of Megakaryocyte and platelet inhibitory receptor G6b - Isoform E of Megakaryocyte and platelet inhibitory receptor G6b - Isoform F of Megakaryocyte and platelet inhibitory receptor G6b - Isoform G of Megakaryocyte and platelet inhibitory receptor G6b

Sequence View

        10         20         30         40         50         60
MAVFLQLLPL LLSRAQGNPG ASLDGRPGDR VNLSCGGVSH PIRWVWAPSF PACKGLSKGR
        70         80         90        100        110        120
RPILWASSSG TPTVPPLQPF VGRLRSLDSG IRRLELLLSA GDSGTFFCKG RHEDESRTVL
       130        140        150        160        170        180
HVLGDRTYCK APGPTHGSVY PQLLIPLLGA GLVLGLGALG LVWWLHRRLP PQPIRPLPRF
       190        200        210        220        230        240
APLVKTEPQR PVKEEEPKIP GDLDQEPSLL YADLDHLALS RPRRLSTADP ADASTIYAVV

V         10         20         30         40         50         60
MAVFLQLLPL LLSRAQGNPG ASLDGRPGDR VNLSCGGVSH PIRWVWAPSF PACKGLSKGR
        70         80         90        100        110        120
RPILWASSSG TPTVPPLQPF VGRLRSLDSG IRRLELLLSA GDSGTFFCKG RHEDESRTVL
       130        140        150        160        170        180
HVLGDRTYCK APGPTHGSVY PQLLIPLLGA GLVLGLGALG LVWWLHRRLP PQPIRPLPRF
       190        200        210        220        230        240
APLVKTEPQR PVKEEEPKIP GDLDQEPSLL YADLDHLALS RPRRLSTADP ADASTIYAVV

V         10         20         30         40         50         60
MAVFLQLLPL LLSRAQGNPG ASLDGRPGDR VNLSCGGVSH PIRWVWAPSF PACKGLSKGR
        70         80         90        100        110        120
RPILWASSSG TPTVPPLQPF VGRLRSLDSG IRRLELLLSA GDSGTFFCKG RHEDESRTVL
       130        140        150        160        170        180
HVLGDRTYCK APGPTHGSVY PQLLIPLLGA GLVLGLGALG LVWWLHRRLP PQPIRPLPRF
       190        200        210        220        230        240
APLVKTEPQR PVKEEEPKIP GDLDQEPSLL YADLDHLALS RPRRLSTADP ADASTIYAVV

V         10         20         30         40         50         60
MAVFLQLLPL LLSRAQGNPG ASLDGRPGDR VNLSCGGVSH PIRWVWAPSF PACKGLSKGR
        70         80         90        100        110        120
RPILWASSSG TPTVPPLQPF VGRLRSLDSG IRRLELLLSA GDSGTFFCKG RHEDESRTVL
       130        140        150        160        170        180
HVLGDRTYCK APGPTHGSVY PQLLIPLLGA GLVLGLGALG LVWWLHRRLP PQPIRPLPRF
       190        200        210        220        230        240
APLVKTEPQR PVKEEEPKIP GDLDQEPSLL YADLDHLALS RPRRLSTADP ADASTIYAVV

V         10         20         30         40         50         60
MAVFLQLLPL LLSRAQGNPG ASLDGRPGDR VNLSCGGVSH PIRWVWAPSF PACKGLSKGR
        70         80         90        100        110        120
RPILWASSSG TPTVPPLQPF VGRLRSLDSG IRRLELLLSA GDSGTFFCKG RHEDESRTVL
       130        140        150        160        170        180
HVLGDRTYCK APGPTHGSVY PQLLIPLLGA GLVLGLGALG LVWWLHRRLP PQPIRPLPRF
       190        200        210        220        230        240
APLVKTEPQR PVKEEEPKIP GDLDQEPSLL YADLDHLALS RPRRLSTADP ADASTIYAVV

V         10         20         30         40         50         60
MAVFLQLLPL LLSRAQGNPG ASLDGRPGDR VNLSCGGVSH PIRWVWAPSF PACKGLSKGR
        70         80         90        100        110        120
RPILWASSSG TPTVPPLQPF VGRLRSLDSG IRRLELLLSA GDSGTFFCKG RHEDESRTVL
       130        140        150        160        170        180
HVLGDRTYCK APGPTHGSVY PQLLIPLLGA GLVLGLGALG LVWWLHRRLP PQPIRPLPRF
       190        200        210        220        230        240
APLVKTEPQR PVKEEEPKIP GDLDQEPSLL YADLDHLALS RPRRLSTADP ADASTIYAVV

V         10         20         30         40         50         60
MAVFLQLLPL LLSRAQGNPG ASLDGRPGDR VNLSCGGVSH PIRWVWAPSF PACKGLSKGR
        70         80         90        100        110        120
RPILWASSSG TPTVPPLQPF VGRLRSLDSG IRRLELLLSA GDSGTFFCKG RHEDESRTVL
       130        140        150        160        170        180
HVLGDRTYCK APGPTHGSVY PQLLIPLLGA GLVLGLGALG LVWWLHRRLP PQPIRPLPRF
       190        200        210        220        230        240
APLVKTEPQR PVKEEEPKIP GDLDQEPSLL YADLDHLALS RPRRLSTADP ADASTIYAVV

V         10         20         30         40         50         60
MAVFLQLLPL LLSRAQGNPG ASLDGRPGDR VNLSCGGVSH PIRWVWAPSF PACKGLSKGR
        70         80         90        100        110        120
RPILWASSSG TPTVPPLQPF VGRLRSLDSG IRRLELLLSA GDSGTFFCKG RHEDESRTVL
       130        140        150        160        170        180
HVLGDRTYCK APGPTHGSVY PQLLIPLLGA GLVLGLGALG LVWWLHRRLP PQPIRPLPRF
       190        200        210        220        230        240
APLVKTEPQR PVKEEEPKIP GDLDQEPSLL YADLDHLALS RPRRLSTADP ADASTIYAVV

V         10         20         30         40         50         60
MAVFLQLLPL LLSRAQGNPG ASLDGRPGDR VNLSCGGVSH PIRWVWAPSF PACKGLSKGR
        70         80         90        100        110        120
RPILWASSSG TPTVPPLQPF VGRLRSLDSG IRRLELLLSA GDSGTFFCKG RHEDESRTVL
       130        140        150        160        170        180
HVLGDRTYCK APGPTHGSVY PQLLIPLLGA GLVLGLGALG LVWWLHRRLP PQPIRPLPRF
       190        200        210        220        230        240
APLVKTEPQR PVKEEEPKIP GDLDQEPSLL YADLDHLALS RPRRLSTADP ADASTIYAVV

V         10         20         30         40         50         60
MAVFLQLLPL LLSRAQGNPG ASLDGRPGDR VNLSCGGVSH PIRWVWAPSF PACKGLSKGR
        70         80         90        100        110        120
RPILWASSSG TPTVPPLQPF VGRLRSLDSG IRRLELLLSA GDSGTFFCKG RHEDESRTVL
       130        140        150        160        170        180
HVLGDRTYCK APGPTHGSVY PQLLIPLLGA GLVLGLGALG LVWWLHRRLP PQPIRPLPRF
       190        200        210        220        230        240
APLVKTEPQR PVKEEEPKIP GDLDQEPSLL YADLDHLALS RPRRLSTADP ADASTIYAVV

V         10         20         30         40         50         60
MAVFLQLLPL LLSRAQGNPG ASLDGRPGDR VNLSCGGVSH PIRWVWAPSF PACKGLSKGR
        70         80         90        100        110        120
RPILWASSSG TPTVPPLQPF VGRLRSLDSG IRRLELLLSA GDSGTFFCKG RHEDESRTVL
       130        140        150        160        170        180
HVLGDRTYCK APGPTHGSVY PQLLIPLLGA GLVLGLGALG LVWWLHRRLP PQPIRPLPRF
       190        200        210        220        230        240
APLVKTEPQR PVKEEEPKIP GDLDQEPSLL YADLDHLALS RPRRLSTADP ADASTIYAVV

V         10         20         30         40         50         60
MAVFLQLLPL LLSRAQGNPG ASLDGRPGDR VNLSCGGVSH PIRWVWAPSF PACKGLSKGR
        70         80         90        100        110        120
RPILWASSSG TPTVPPLQPF VGRLRSLDSG IRRLELLLSA GDSGTFFCKG RHEDESRTVL
       130        140        150        160        170        180
HVLGDRTYCK APGPTHGSVY PQLLIPLLGA GLVLGLGALG LVWWLHRRLP PQPIRPLPRF
       190        200        210        220        230        240
APLVKTEPQR PVKEEEPKIP GDLDQEPSLL YADLDHLALS RPRRLSTADP ADASTIYAVV

V

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O95866-1-unknown	MAVFLQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt75632
O95866-1-unknown	MAVFLQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt75633
O95866-1-unknown	MAVFLQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt75634
O95866-1-unknown	MAVFLQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt75635
O95866-1-unknown	MAVFLQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt75636
O95866-1-unknown	MAVFLQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt75637
O95866-18-unknown	NPGASL...	18	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O95866-18-unknown	NPGASL...	18	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111943
O95866-18-unknown	NPGASL...	18	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111944
O95866-18-unknown	NPGASL...	18	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111945
O95866-18-unknown	NPGASL...	18	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111946
O95866-18-unknown	NPGASL...	18	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111947
O95866-18-unknown	NPGASL...	18	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111948

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...YAVVV	241	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...YAVVV	241	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt71253
...YAVVV	241	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt71251

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)