TopFIND 4.0

O95870: Phosphatidylserine lipase ABHD16A {ECO:0000305}

General Information

Protein names
- Phosphatidylserine lipase ABHD16A {ECO:0000305}
- 3.1.-.- {ECO:0000250|UniProtKB:Q9Z1Q2}
- Alpha/beta hydrolase domain-containing protein 16A {ECO:0000305}
- Abhydrolase domain-containing protein 16A {ECO:0000305}
- HLA-B-associated transcript 5 {ECO:0000303|PubMed:25290914}
- hBAT5 {ECO:0000303|PubMed:25290914}
- Monoacylglycerol lipase ABHD16A {ECO:0000305}
- 3.1.1.23 {ECO:0000269|PubMed:25290914}
- Protein G5
Gene names ABHD16A
Organism Homo sapiens
Protease Family
Protease ID S09.065
Chromosome location
UniProt ID O95870

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAKLLSCVLG PRLYKIYRER DSERAPASVP ETPTAVTAPH SSSWDTYYQP RALEKHADSI 
        70         80         90        100        110        120 
LALASVFWSI SYYSSPFAFF YLYRKGYLSL SKVVPFSHYA GTLLLLLAGV ACLRGIGRWT 
       130        140        150        160        170        180 
NPQYRQFITI LEATHRNQSS ENKRQLANYN FDFRSWPVDF HWEEPSSRKE SRGGPSRRGV 
       190        200        210        220        230        240 
ALLRPEPLHR GTADTLLNRV KKLPCQITSY LVAHTLGRRM LYPGSVYLLQ KALMPVLLQG 
       250        260        270        280        290        300 
QARLVEECNG RRAKLLACDG NEIDTMFVDR RGTAEPQGQK LVICCEGNAG FYEVGCVSTP 
       310        320        330        340        350        360 
LEAGYSVLGW NHPGFAGSTG VPFPQNEANA MDVVVQFAIH RLGFQPQDII IYAWSIGGFT 
       370        380        390        400        410        420 
ATWAAMSYPD VSAMILDASF DDLVPLALKV MPDSWRGLVT RTVRQHLNLN NAEQLCRYQG 
       430        440        450        460        470        480 
PVLLIRRTKD EIITTTVPED IMSNRGNDLL LKLLQHRYPR VMAEEGLRVV RQWLEASSQL 
       490        500        510        520        530        540 
EEASIYSRWE VEEDWCLSVL RSYQAEHGPD FPWSVGEDMS ADGRRQLALF LARKHLHNFE 
       550    
ATHCTPLPAQ NFQMPWHL

Isoforms

- Isoform 2 of Abhydrolase domain-containing protein 16A - Isoform 2 of Phosphatidylserine lipase ABHD16A

Sequence View

        10         20         30         40         50         60 
MAKLLSCVLG PRLYKIYRER DSERAPASVP ETPTAVTAPH SSSWDTYYQP RALEKHADSI 
        70         80         90        100        110        120 
LALASVFWSI SYYSSPFAFF YLYRKGYLSL SKVVPFSHYA GTLLLLLAGV ACLRGIGRWT 
       130        140        150        160        170        180 
NPQYRQFITI LEATHRNQSS ENKRQLANYN FDFRSWPVDF HWEEPSSRKE SRGGPSRRGV 
       190        200        210        220        230        240 
ALLRPEPLHR GTADTLLNRV KKLPCQITSY LVAHTLGRRM LYPGSVYLLQ KALMPVLLQG 
       250        260        270        280        290        300 
QARLVEECNG RRAKLLACDG NEIDTMFVDR RGTAEPQGQK LVICCEGNAG FYEVGCVSTP 
       310        320        330        340        350        360 
LEAGYSVLGW NHPGFAGSTG VPFPQNEANA MDVVVQFAIH RLGFQPQDII IYAWSIGGFT 
       370        380        390        400        410        420 
ATWAAMSYPD VSAMILDASF DDLVPLALKV MPDSWRGLVT RTVRQHLNLN NAEQLCRYQG 
       430        440        450        460        470        480 
PVLLIRRTKD EIITTTVPED IMSNRGNDLL LKLLQHRYPR VMAEEGLRVV RQWLEASSQL 
       490        500        510        520        530        540 
EEASIYSRWE VEEDWCLSVL RSYQAEHGPD FPWSVGEDMS ADGRRQLALF LARKHLHNFE 
       550    
ATHCTPLPAQ NFQMPWHL         10         20         30         40         50         60 
MAKLLSCVLG PRLYKIYRER DSERAPASVP ETPTAVTAPH SSSWDTYYQP RALEKHADSI 
        70         80         90        100        110        120 
LALASVFWSI SYYSSPFAFF YLYRKGYLSL SKVVPFSHYA GTLLLLLAGV ACLRGIGRWT 
       130        140        150        160        170        180 
NPQYRQFITI LEATHRNQSS ENKRQLANYN FDFRSWPVDF HWEEPSSRKE SRGGPSRRGV 
       190        200        210        220        230        240 
ALLRPEPLHR GTADTLLNRV KKLPCQITSY LVAHTLGRRM LYPGSVYLLQ KALMPVLLQG 
       250        260        270        280        290        300 
QARLVEECNG RRAKLLACDG NEIDTMFVDR RGTAEPQGQK LVICCEGNAG FYEVGCVSTP 
       310        320        330        340        350        360 
LEAGYSVLGW NHPGFAGSTG VPFPQNEANA MDVVVQFAIH RLGFQPQDII IYAWSIGGFT 
       370        380        390        400        410        420 
ATWAAMSYPD VSAMILDASF DDLVPLALKV MPDSWRGLVT RTVRQHLNLN NAEQLCRYQG 
       430        440        450        460        470        480 
PVLLIRRTKD EIITTTVPED IMSNRGNDLL LKLLQHRYPR VMAEEGLRVV RQWLEASSQL 
       490        500        510        520        530        540 
EEASIYSRWE VEEDWCLSVL RSYQAEHGPD FPWSVGEDMS ADGRRQLALF LARKHLHNFE 
       550    
ATHCTPLPAQ NFQMPWHL



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...MPWHL 558 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...MPWHL 558 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt61638

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)