TopFIND 4.0

O95922: Probable tubulin polyglutamylase TTLL1

General Information

Protein names
- Probable tubulin polyglutamylase TTLL1
- 6.-.-.-
- Tubulin polyglutamylase complex subunit 3
- PGs3
- Tubulin--tyrosine ligase-like protein 1
Gene names TTLL1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID O95922

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAGKVKWVTD IEKSVLINNF EKRGWVQVTE NEDWNFYWMS VQTIRNVFSV EAGYRLSDDQ 
        70         80         90        100        110        120 
IVNHFPNHYE LTRKDLMVKN IKRYRKELEK EGSPLAEKDE NGKYLYLDFV PVTYMLPADY 
       130        140        150        160        170        180 
NLFVEEFRKS PSSTWIMKPC GKAQGKGIFL INKLSQIKKW SRDSKTSSFV SQSNKEAYVI 
       190        200        210        220        230        240 
SLYINNPLLI GGRKFDLRLY VLVSTYRPLR CYMYKLGFCR FCTVKYTPST SELDNMFVHL 
       250        260        270        280        290        300 
TNVAIQKHGE DYNHIHGGKW TVSNLRLYLE STRGKEVTSK LFDEIHWIIV QSLKAVAPVM 
       310        320        330        340        350        360 
NNDKHCFECY GYDIIIDDKL KPWLIEVNAS PSLTSSTAND RILKYNLIND TLNIAVPNGE 
       370        380        390        400        410        420 
IPDCKWNKSP PKEVLGNYEI LYDEELAQGD GADRELRSRQ GQSLGPRAGR SRDSGRAVLT 
   
TWK

Isoforms

- Isoform B of Probable tubulin polyglutamylase TTLL1 - Isoform 4 of Probable tubulin polyglutamylase TTLL1

Sequence View

        10         20         30         40         50         60 
MAGKVKWVTD IEKSVLINNF EKRGWVQVTE NEDWNFYWMS VQTIRNVFSV EAGYRLSDDQ 
        70         80         90        100        110        120 
IVNHFPNHYE LTRKDLMVKN IKRYRKELEK EGSPLAEKDE NGKYLYLDFV PVTYMLPADY 
       130        140        150        160        170        180 
NLFVEEFRKS PSSTWIMKPC GKAQGKGIFL INKLSQIKKW SRDSKTSSFV SQSNKEAYVI 
       190        200        210        220        230        240 
SLYINNPLLI GGRKFDLRLY VLVSTYRPLR CYMYKLGFCR FCTVKYTPST SELDNMFVHL 
       250        260        270        280        290        300 
TNVAIQKHGE DYNHIHGGKW TVSNLRLYLE STRGKEVTSK LFDEIHWIIV QSLKAVAPVM 
       310        320        330        340        350        360 
NNDKHCFECY GYDIIIDDKL KPWLIEVNAS PSLTSSTAND RILKYNLIND TLNIAVPNGE 
       370        380        390        400        410        420 
IPDCKWNKSP PKEVLGNYEI LYDEELAQGD GADRELRSRQ GQSLGPRAGR SRDSGRAVLT 
   
TWK         10         20         30         40         50         60 
MAGKVKWVTD IEKSVLINNF EKRGWVQVTE NEDWNFYWMS VQTIRNVFSV EAGYRLSDDQ 
        70         80         90        100        110        120 
IVNHFPNHYE LTRKDLMVKN IKRYRKELEK EGSPLAEKDE NGKYLYLDFV PVTYMLPADY 
       130        140        150        160        170        180 
NLFVEEFRKS PSSTWIMKPC GKAQGKGIFL INKLSQIKKW SRDSKTSSFV SQSNKEAYVI 
       190        200        210        220        230        240 
SLYINNPLLI GGRKFDLRLY VLVSTYRPLR CYMYKLGFCR FCTVKYTPST SELDNMFVHL 
       250        260        270        280        290        300 
TNVAIQKHGE DYNHIHGGKW TVSNLRLYLE STRGKEVTSK LFDEIHWIIV QSLKAVAPVM 
       310        320        330        340        350        360 
NNDKHCFECY GYDIIIDDKL KPWLIEVNAS PSLTSSTAND RILKYNLIND TLNIAVPNGE 
       370        380        390        400        410        420 
IPDCKWNKSP PKEVLGNYEI LYDEELAQGD GADRELRSRQ GQSLGPRAGR SRDSGRAVLT 
   
TWK



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    O95922-1-unknown MAGKVK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    O95922-1-unknown MAGKVK... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt93393
    O95922-1-unknown MAGKVK... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt93394

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LTTWK 423 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LTTWK 423 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt89012

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)