O95954: Formimidoyltransferase-cyclodeaminase

General Information

Protein names	- Formimidoyltransferase-cyclodeaminase - Formiminotransferase-cyclodeaminase - FTCD - LCHC1 - Glutamate formimidoyltransferase - 2.1.2.5 - Glutamate formiminotransferase - Glutamate formyltransferase - Formimidoyltetrahydrofolate cyclodeaminase - 4.3.1.4 - Formiminotetrahydrofolate cyclodeaminase
Gene names	FTCD
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O95954

1 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSQLVECVPN FSEGKNQEVI DAISGAITQT PGCVLLDVDA GPSTNRTVYT FVGPPECVVE
        70         80         90        100        110        120
GALNAARVAS RLIDMSRHQG EHPRMGALDV CPFIPVRGVS VDECVLCAQA FGQRLAEELD
       130        140        150        160        170        180
VPVYLYGEAA RMDSRRTLPA IRAGEYEALP KKLQQADWAP DFGPSSFVPS WGATATGARK
       190        200        210        220        230        240
FLIAFNINLL GTKEQAHRIA LNLREQGRGK DQPGRLKKVQ GIGWYLDEKN LAQVSTNLLD
       250        260        270        280        290        300
FEVTALHTVY EETCREAQEL SLPVVGSQLV GLVPLKALLD AAAFYCEKEN LFILEEEQRI
       310        320        330        340        350        360
RLVVSRLGLD SLCPFSPKER IIEYLVPERG PERGLGSKSL RAFVGEVGAR SAAPGGGSVA
       370        380        390        400        410        420
AAAAAMGAAL GSMVGLMTYG RRQFQSLDTT MRRLIPPFRE ASAKLTTLVD ADAEAFTAYL
       430        440        450        460        470        480
EAMRLPKNTP EEKDRRTAAL QEGLRRAVSV PLTLAETVAS LWPALQELAR CGNLACRSDL
       490        500        510        520        530        540
QVAAKALEMG VFGAYFNVLI NLRDITDEAF KDQIHHRVSS LLQEAKTQAA LVLDCLETRQ

E

Isoforms

- Isoform C of Formimidoyltransferase-cyclodeaminase - Isoform D of Formimidoyltransferase-cyclodeaminase - Isoform E of Formimidoyltransferase-cyclodeaminase

Sequence View

        10         20         30         40         50         60
MSQLVECVPN FSEGKNQEVI DAISGAITQT PGCVLLDVDA GPSTNRTVYT FVGPPECVVE
        70         80         90        100        110        120
GALNAARVAS RLIDMSRHQG EHPRMGALDV CPFIPVRGVS VDECVLCAQA FGQRLAEELD
       130        140        150        160        170        180
VPVYLYGEAA RMDSRRTLPA IRAGEYEALP KKLQQADWAP DFGPSSFVPS WGATATGARK
       190        200        210        220        230        240
FLIAFNINLL GTKEQAHRIA LNLREQGRGK DQPGRLKKVQ GIGWYLDEKN LAQVSTNLLD
       250        260        270        280        290        300
FEVTALHTVY EETCREAQEL SLPVVGSQLV GLVPLKALLD AAAFYCEKEN LFILEEEQRI
       310        320        330        340        350        360
RLVVSRLGLD SLCPFSPKER IIEYLVPERG PERGLGSKSL RAFVGEVGAR SAAPGGGSVA
       370        380        390        400        410        420
AAAAAMGAAL GSMVGLMTYG RRQFQSLDTT MRRLIPPFRE ASAKLTTLVD ADAEAFTAYL
       430        440        450        460        470        480
EAMRLPKNTP EEKDRRTAAL QEGLRRAVSV PLTLAETVAS LWPALQELAR CGNLACRSDL
       490        500        510        520        530        540
QVAAKALEMG VFGAYFNVLI NLRDITDEAF KDQIHHRVSS LLQEAKTQAA LVLDCLETRQ

E         10         20         30         40         50         60
MSQLVECVPN FSEGKNQEVI DAISGAITQT PGCVLLDVDA GPSTNRTVYT FVGPPECVVE
        70         80         90        100        110        120
GALNAARVAS RLIDMSRHQG EHPRMGALDV CPFIPVRGVS VDECVLCAQA FGQRLAEELD
       130        140        150        160        170        180
VPVYLYGEAA RMDSRRTLPA IRAGEYEALP KKLQQADWAP DFGPSSFVPS WGATATGARK
       190        200        210        220        230        240
FLIAFNINLL GTKEQAHRIA LNLREQGRGK DQPGRLKKVQ GIGWYLDEKN LAQVSTNLLD
       250        260        270        280        290        300
FEVTALHTVY EETCREAQEL SLPVVGSQLV GLVPLKALLD AAAFYCEKEN LFILEEEQRI
       310        320        330        340        350        360
RLVVSRLGLD SLCPFSPKER IIEYLVPERG PERGLGSKSL RAFVGEVGAR SAAPGGGSVA
       370        380        390        400        410        420
AAAAAMGAAL GSMVGLMTYG RRQFQSLDTT MRRLIPPFRE ASAKLTTLVD ADAEAFTAYL
       430        440        450        460        470        480
EAMRLPKNTP EEKDRRTAAL QEGLRRAVSV PLTLAETVAS LWPALQELAR CGNLACRSDL
       490        500        510        520        530        540
QVAAKALEMG VFGAYFNVLI NLRDITDEAF KDQIHHRVSS LLQEAKTQAA LVLDCLETRQ

E         10         20         30         40         50         60
MSQLVECVPN FSEGKNQEVI DAISGAITQT PGCVLLDVDA GPSTNRTVYT FVGPPECVVE
        70         80         90        100        110        120
GALNAARVAS RLIDMSRHQG EHPRMGALDV CPFIPVRGVS VDECVLCAQA FGQRLAEELD
       130        140        150        160        170        180
VPVYLYGEAA RMDSRRTLPA IRAGEYEALP KKLQQADWAP DFGPSSFVPS WGATATGARK
       190        200        210        220        230        240
FLIAFNINLL GTKEQAHRIA LNLREQGRGK DQPGRLKKVQ GIGWYLDEKN LAQVSTNLLD
       250        260        270        280        290        300
FEVTALHTVY EETCREAQEL SLPVVGSQLV GLVPLKALLD AAAFYCEKEN LFILEEEQRI
       310        320        330        340        350        360
RLVVSRLGLD SLCPFSPKER IIEYLVPERG PERGLGSKSL RAFVGEVGAR SAAPGGGSVA
       370        380        390        400        410        420
AAAAAMGAAL GSMVGLMTYG RRQFQSLDTT MRRLIPPFRE ASAKLTTLVD ADAEAFTAYL
       430        440        450        460        470        480
EAMRLPKNTP EEKDRRTAAL QEGLRRAVSV PLTLAETVAS LWPALQELAR CGNLACRSDL
       490        500        510        520        530        540
QVAAKALEMG VFGAYFNVLI NLRDITDEAF KDQIHHRVSS LLQEAKTQAA LVLDCLETRQ

E

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O95954-1-unknown	MSQLVE...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O95954-1-unknown	MSQLVE...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt75516
O95954-1-unknown	MSQLVE...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt75517
O95954-1-unknown	MSQLVE...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt75518

TopFIND

O95954: Formimidoyltransferase-cyclodeaminase

General Information

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates