O95989: Diphosphoinositol polyphosphate phosphohydrolase 1 {ECO:0000305}

General Information

Protein names	- Diphosphoinositol polyphosphate phosphohydrolase 1 {ECO:0000305} - DIPP-1 - 3.6.1.52 {ECO:0000269\|PubMed:10419486, ECO:0000269\|PubMed:12370170, ECO:0000269\|PubMed:9822604} - Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1 - 3.6.1.- - Nucleoside diphosphate-linked moiety X motif 3 - Nudix motif 3
Gene names	NUDT3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O95989

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MMKLKSNQTR TYDGDGYKKR AACLCFRSES EEEVLLVSSS RHPDRWIVPG GGMEPEEEPS
        70         80         90        100        110        120
VAAVREVCEE AGVKGTLGRL VGIFENQERK HRTYVYVLIV TEVLEDWEDS VNIGRKREWF
       130        140        150        160        170
KIEDAIKVLQ YHKPVQASYF ETLRQGYSAN NGTPVVATTY SVSAQSSMSG IR

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O95989-1-Acetylation	MMKLKS...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O95989-1-Acetylation	MMKLKS...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
O95989-1-Acetylation	MMKLKS...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
O95989-2-unknown	MKLKSN...	2			COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
O95989-2-unknown	MKLKSN...	2			COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
O95989-161-	SVSAQS...	161			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
O95989-161-	SVSAQS...	161			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...MSGIR	172	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)