O95995: Dynein regulatory complex subunit 4 {ECO:0000303|PubMed:27120127}

General Information

Protein names	- Dynein regulatory complex subunit 4 {ECO:0000303\|PubMed:27120127} - Growth arrest-specific protein 11 - GAS-11 - Growth arrest-specific protein 8 - GAS-8
Gene names	GAS8
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O95995

3 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Growth arrest-specific protein 8 - Isoform 2 of Dynein regulatory complex subunit 4

Sequence View

        10         20         30         40         50         60
MAPKKKGKKG KAKGTPIVDG LAPEDMSKEQ VEEHVSRIRE ELDREREERN YFQLERDKIH
        70         80         90        100        110        120
TFWEITRRQL EEKKAELRNK DREMEEAEER HQVEIKVYKQ KVKHLLYEHQ NNLTEMKAEG
       130        140        150        160        170        180
TVVMKLAQKE HRIQESVLRK DMRALKVELK EQELASEVVV KNLRLKHTEE ITRMRNDFER
       190        200        210        220        230        240
QVREIEAKYD KKMKMLRDEL DLRRKTELHE VEERKNGQIH TLMQRHEEAF TDIKNYYNDI
       250        260        270        280        290        300
TLNNLALINS LKEQMEDMRK KEDHLEREMA EVSGQNKRLA DPLQKAREEM SEMQKQLANY
       310        320        330        340        350        360
ERDKQILLCT KARLKVREKE LKDLQWEHEV LEQRFTKVQQ ERDELYRKFT AAIQEVQQKT
       370        380        390        400        410        420
GFKNLVLERK LQALSAAVEK KEVQFNEVLA ASNLDPAALT LVSRKLEDVL ESKNSTIKDL
       430        440        450        460        470
QYELAQVCKA HNDLLRTYEA KLLAFGIPLD NVGFKPLETA VIGQTLGQGP AGLVGTPT         10         20         30         40         50         60
MAPKKKGKKG KAKGTPIVDG LAPEDMSKEQ VEEHVSRIRE ELDREREERN YFQLERDKIH
        70         80         90        100        110        120
TFWEITRRQL EEKKAELRNK DREMEEAEER HQVEIKVYKQ KVKHLLYEHQ NNLTEMKAEG
       130        140        150        160        170        180
TVVMKLAQKE HRIQESVLRK DMRALKVELK EQELASEVVV KNLRLKHTEE ITRMRNDFER
       190        200        210        220        230        240
QVREIEAKYD KKMKMLRDEL DLRRKTELHE VEERKNGQIH TLMQRHEEAF TDIKNYYNDI
       250        260        270        280        290        300
TLNNLALINS LKEQMEDMRK KEDHLEREMA EVSGQNKRLA DPLQKAREEM SEMQKQLANY
       310        320        330        340        350        360
ERDKQILLCT KARLKVREKE LKDLQWEHEV LEQRFTKVQQ ERDELYRKFT AAIQEVQQKT
       370        380        390        400        410        420
GFKNLVLERK LQALSAAVEK KEVQFNEVLA ASNLDPAALT LVSRKLEDVL ESKNSTIKDL
       430        440        450        460        470
QYELAQVCKA HNDLLRTYEA KLLAFGIPLD NVGFKPLETA VIGQTLGQGP AGLVGTPT

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
O95995-1-unknown	MAPKKK...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
O95995-26-unknown	MSKEQV...	26	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt75729
O95995-26-unknown	MSKEQV...	26	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454905
O95995-26-unknown	MSKEQV...	26	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000455172
O95995-26-unknown	MSKEQV...	26	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000440977
O95995-84-unknown	MEEAEE...	84	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457554
O95995-84-unknown	MEEAEE...	84	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt130772

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...MKAEGT	120	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000455172
...MKAEGT	120	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt110416
...LRKDMR	142	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454905
...LRKDMR	142	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt110412
...RKDMRA	143	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000457554
...RKDMRA	143	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt110414
...VGTPT	478	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...VGTPT	478	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt71347

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)