O96009: Napsin-A
| Protein names | - Napsin-A - 3.4.23.- - Aspartyl protease 4 - ASP4 - Asp 4 - Napsin-1 - TA01/TA02 |
|---|---|
| Gene names | NAPSA |
| Organism | Homo sapiens |
| Protease Family | A01.046 |
| Protease ID | A01.046 |
| Chromosome location | |
| UniProt ID | O96009 |
2
N-termini
2
C-termini
0
Cleavages
3
Substrates
Sequence
10 20 30 40 50 60
MSPPPLLQPL LLLLPLLNVE PSGATLIRIP LHRVQPGRRI LNLLRGWREP AELPKLGAPS
70 80 90 100 110 120
PGDKPIFVPL SNYRDVQYFG EIGLGTPPQN FTVAFDTGSS NLWVPSRRCH FFSVPCWLHH
130 140 150 160 170 180
RFDPKASSSF QANGTKFAIQ YGTGRVDGIL SEDKLTIGGI KGASVIFGEA LWEPSLVFAF
190 200 210 220 230 240
AHFDGILGLG FPILSVEGVR PPMDVLVEQG LLDKPVFSFY LNRDPEEPDG GELVLGGSDP
250 260 270 280 290 300
AHYIPPLTFV PVTVPAYWQI HMERVKVGPG LTLCAKGCAA ILDTGTSLIT GPTEEIRALH
310 320 330 340 350 360
AAIGGIPLLA GEYIILCSEI PKLPAVSFLL GGVWFNLTAH DYVIQTTRNG VRLCLSGFQA
370 380 390 400 410 420
LDVPPPAGPF WILGDVFLGT YVAVFDRGDM KSSARVGLAR ARTRGADLGW GETAQAQFPG
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 0 Cleavages - 3 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| O96009-26-unknown | LIRIPL... | 26 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| O96009-64-unknown | KPIFVP... | 64 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...LCAKGC | 277 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000469061 | |||
| ...AQFPG | 420 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| PSPB_HUMAN | 178 | LVLP.|.PVLP | inferred from experiment | unknown | MEROPS | Weaver TE | Ueno T et al.:Processing of pulmonary surfact... (C01.040) | 14766755, |
| PSPB_HUMAN | 180 | LPVL.|.LPGA | inferred from experiment | unknown | MEROPS | Buhling F | Brasch F et al.:Involvement of napsin A in the ... (A01.046) | 13129928, |
| PSPB_HUMAN | 354 | RGWD.|.DAHT | inferred from experiment | unknown | MEROPS | Buhling F | Brasch F et al.:Involvement of napsin A in the ... (A01.046) | 13129928, |