TopFIND 4.0

P00562: Bifunctional aspartokinase/homoserine dehydrogenase 2

General Information

Protein names
- Bifunctional aspartokinase/homoserine dehydrogenase 2
- Aspartokinase II/homoserine dehydrogenase II
- AKII-HDII
- Aspartokinase
- 2.7.2.4
- Homoserine dehydrogenase
- 1.1.1.3
Gene names metL
Organism Escherichia coli
Protease Family
Protease ID
Chromosome location
UniProt ID P00562

1

N-termini

1

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSVIAQAGAK GRQLHKFGGS SLADVKCYLR VAGIMAEYSQ PDDMMVVSAA GSTTNQLINW 
        70         80         90        100        110        120 
LKLSQTDRLS AHQVQQTLRR YQCDLISGLL PAEEADSLIS AFVSDLERLA ALLDSGINDA 
       130        140        150        160        170        180 
VYAEVVGHGE VWSARLMSAV LNQQGLPAAW LDAREFLRAE RAAQPQVDEG LSYPLLQQLL 
       190        200        210        220        230        240 
VQHPGKRLVV TGFISRNNAG ETVLLGRNGS DYSATQIGAL AGVSRVTIWS DVAGVYSADP 
       250        260        270        280        290        300 
RKVKDACLLP LLRLDEASEL ARLAAPVLHA RTLQPVSGSE IDLQLRCSYT PDQGSTRIER 
       310        320        330        340        350        360 
VLASGTGARI VTSHDDVCLI EFQVPASQDF KLAHKEIDQI LKRAQVRPLA VGVHNDRQLL 
       370        380        390        400        410        420 
QFCYTSEVAD SALKILDEAG LPGELRLRQG LALVAMVGAG VTRNPLHCHR FWQQLKGQPV 
       430        440        450        460        470        480 
EFTWQSDDGI SLVAVLRTGP TESLIQGLHQ SVFRAEKRIG LVLFGKGNIG SRWLELFARE 
       490        500        510        520        530        540 
QSTLSARTGF EFVLAGVVDS RRSLLSYDGL DASRALAFFN DEAVEQDEES LFLWMRAHPY 
       550        560        570        580        590        600 
DDLVVLDVTA SQQLADQYLD FASHGFHVIS ANKLAGASDS NKYRQIHDAF EKTGRHWLYN 
       610        620        630        640        650        660 
ATVGAGLPIN HTVRDLIDSG DTILSISGIF SGTLSWLFLQ FDGSVPFTEL VDQAWQQGLT 
       670        680        690        700        710        720 
EPDPRDDLSG KDVMRKLVIL AREAGYNIEP DQVRVESLVP AHCEGGSIDH FFENGDELNE 
       730        740        750        760        770        780 
QMVQRLEAAR EMGLVLRYVA RFDANGKARV GVEAVREDHP LASLLPCDNV FAIESRWYRD 
       790        800        810    
NPLVIRGPGA GRDVTAGAIQ SDINRLAQLL 

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 1 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P00562-2-unknown SVIAQA... 2 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P00562-2-unknown SVIAQA... 2 inferred from cleavage unknown TopFIND Inferred from cleavage TC28026

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LAQLL 810 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)