P01026: Complement C3
| Protein names | - Complement C3 - Complement C3 beta chain - C3-beta-c - C3bc - Neutrophil chemotactic factor-2 - ENCF-2 - Complement C3 alpha chain - C3a anaphylatoxin - Neutrophil chemotactic factor-1 - ENCF-1 - Acylation stimulating protein - ASP - C3adesArg - Complement C3b alpha' chain - Complement C3c alpha' chain fragment 1 - Complement C3dg fragment - Complement C3g fragment - Complement C3d fragment - Complement C3f fragment - Complement C3c alpha' chain fragment 2 |
|---|---|
| Gene names | C3 |
| Organism | Rattus norvegicus |
| Protease Family | |
| Protease ID | I39.950 |
| Chromosome location | |
| UniProt ID | P01026 |
7
N-termini
7
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MGPTSGSQLL VLLLLLASSL LALGSPMYSI ITPNVLRLES EETFILEAHD AQGDVPVTVT
70 80 90 100 110 120
VQDFLKKQVL TSEKTVLTGA TGHLNRVFIK IPASKEFNAD KGHKYVTVVA NFGATVVEKA
130 140 150 160 170 180
VLVSFQSGYL FIQTDKTIYT PGSTVFYRIF TVDNNLLPVG KTVVIVIETP DGVPIKRDIL
190 200 210 220 230 240
SSHNQYGILP LSWNIPELVN MGQWKIRAFY EHAPKQTFSA EFEVKEYVLP SFEVLVEPTE
250 260 270 280 290 300
KFYYIHGPKG LEVSITARFL YGKNVDGTAF VIFGVQDEDK KISLALSLTR VLIEDGSGEA
310 320 330 340 350 360
VLSRKVLMDG VRPSSPEALV GKSLYVSVTV ILHSGSDMVE AERSGIPIVT SPYQIHFTKT
370 380 390 400 410 420
PKFFKPAMPF DLMVFVTNPD GSPARRVPVV TQGSDAQALT QDDGVAKLSV NTPNNRQPLT
430 440 450 460 470 480
ITVSTKKEGI PDARQATRTM QAQPYSTMHN SNNYLHLSVS RVELKPGDNL NVNFHLRTDA
490 500 510 520 530 540
GQEAKIRYYT YLVMNKGKLL KAGRQVREPG QDLVVLSLPI TPEFIPSFRL VAYYTLIGAN
550 560 570 580 590 600
GQREVVADSV WVDVKDSCVG TLVVKGDPRD NRQPAPGHQT TLRIEGNQGA RVGLVAVDKG
610 620 630 640 650 660
VFVLNKKNKL TQSKIWDVVE KADIGCTPGS GKNYAGVFMD AGLTFKTNQG LQTDQREDPE
670 680 690 700 710 720
CAKPAARRRR SVQLMERRMD KAGQYTDKGL RKCCEDGMRD IPMPYSCQRR ARLITQGESC
730 740 750 760 770 780
LKAFMDCCNY ITKLREQHRR DHVLGLARSD VDEDIIPEED IISRSHFPES WLWTIEELKE
790 800 810 820 830 840
PEKNGISTKV MNIFLKDSIT TWEILAVSLS DKKGICVADP YEITVMQDFF IDLRLPYSVV
850 860 870 880 890 900
RNEQVEIRAV LFNYREQEKL KVRVELLHNP AFCSMATAKK RYYQTIEIPP KSSVAVPYVI
910 920 930 940 950 960
VPLKIGLQEV EVKAAVFNHF ISDGVKKILK VVPEGMRVNK TVAVRTLDPE HLNQGGVQRE
970 980 990 1000 1010 1020
DVNAADLSDQ VPDTDSETRI LLQGTPVAQM AEDAVDGERL KHLIVTPSGC GEQNMIGMTP
1030 1040 1050 1060 1070 1080
TVIAVHYLDQ TEQWEKFGLE KRQEALELIK KGYTQQLAFK QPISAYAAFN NRPPSTWLTA
1090 1100 1110 1120 1130 1140
MWSRSFSLAA NLIAIDSQVL CGAVKWLILE KQKPDGVFQE DGPVIHQEMI GGFRNTKEAD
1150 1160 1170 1180 1190 1200
VSLTAFVLIA LQEARDICEG QVNSLPGSIN KAGEYLEASY LNLQRPYTVA IAGYALALMN
1210 1220 1230 1240 1250 1260
KLEEPYLTKF LNTAKDRNRW EEPGQQLYNV EATSYALLAL LLLKDFDSVP PVVRWLNDER
1270 1280 1290 1300 1310 1320
YYGGGYGSTQ ATFMVFQALA QYRADVPDHK DLNMDVSLHL PSRSSPTVFR LLWESGSLLR
1330 1340 1350 1360 1370 1380
SEETKQNEGF SLTAKGKGQG TLSVVTVYHA KVKGKTTCKK FDLRVTIKPA PETAKKPQDA
1390 1400 1410 1420 1430 1440
KSSMILDICT RYLGDVDATM SILDISMMTG FIPDTNDLEL LSSGVDRYIS KYEMDKAFSN
1450 1460 1470 1480 1490 1500
KNTLIIYLEK ISHSEEDCLS FKVHQFFNVG LIQPGSVKVY SYYNLEESCT RFYHPEKDDG
1510 1520 1530 1540 1550 1560
MLSKLCHNEM CRCAEENCFM HQSQDQVSLN ERLDKACEPG VDYVYKTKLT TIELSDDFDE
1570 1580 1590 1600 1610 1620
YIMTIEQVIK SGSDEVQAGQ ERRFISHVKC RNALKLQKGK QYLMWGLSSD LWGEKPNTSY
1630 1640 1650 1660
IIGKDTWVEH WPEAEERQDQ KNQKQCEDLG AFTETMVVFG CPN
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
7 N-termini - 7 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P01026-25-unknown | SPMYSI... | 25 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P01026-568-unknown | PRDNRQ... | 568 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P01026-671-unknown | SVQLME... | 671 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P01026-749-unknown | SDVDED... | 749 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P01026-960-unknown | EDVNAA... | 960 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P01026-1002-unknown | HLIVTP... | 1002 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P01026-1321-unknown | SEETKQ... | 1321 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...AKPAAR | 666 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...VLGLAR | 747 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...LGLARS | 748 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...GGVQRE | 959 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...GERLKH | 1001 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...HLPSRS | 1303 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...FGCPN | 1663 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|