TopFIND 4.0

P01116: GTPase KRas

General Information

Protein names
- GTPase KRas
- K-Ras 2
- Ki-Ras
- c-K-ras
- c-Ki-ras
- GTPase KRas, N-terminally processed
Gene names KRAS
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P01116

3

N-termini

1

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG 
        70         80         90        100        110        120 
QEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHHYREQI KRVKDSEDVP MVLVGNKCDL 
       130        140        150        160        170        180 
PSRTVDTKQA QDLARSYGIP FIETSAKTRQ RVEDAFYTLV REIRQYRLKK ISKEEKTPGC 
   
VKIKKCIIM

Isoforms

- Isoform 2B of GTPase KRas

Sequence View

        10         20         30         40         50         60 
MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG 
        70         80         90        100        110        120 
QEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHHYREQI KRVKDSEDVP MVLVGNKCDL 
       130        140        150        160        170        180 
PSRTVDTKQA QDLARSYGIP FIETSAKTRQ RVEDAFYTLV REIRQYRLKK ISKEEKTPGC 
   
VKIKKCIIM



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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 1 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P01116-1-unknown MTEYKL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt87008
    P01116-1-Acetylation MTEYKL... 1 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P01116-1-Acetylation MTEYKL... 1 acetylation- inferred from isoform by sequence similarity unknown TopFIND inferred from TNt101606
    P01116-2-Acetylation TEYKLV... 2 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P01116-2-Acetylation TEYKLV... 2 acetylation- inferred from isoform by sequence similarity unknown TopFIND inferred from TNt110769

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)