P01860: Immunoglobulin heavy constant gamma 3 {ECO:0000303|PubMed:11340299, ECO:0000303|Ref.9}
| Protein names | - Immunoglobulin heavy constant gamma 3 {ECO:0000303|PubMed:11340299, ECO:0000303|Ref.9} - HDC - Heavy chain disease protein - Ig gamma-3 chain C region {ECO:0000305} |
|---|---|
| Gene names | IGHG3 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | P01860 |
5
N-termini
3
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
ASTKGPSVFP LAPCSRSTSG GTAALGCLVK DYFPEPVTVS WNSGALTSGV HTFPAVLQSS
70 80 90 100 110 120
GLYSLSSVVT VPSSSLGTQT YTCNVNHKPS NTKVDKRVEL KTPLGDTTHT CPRCPEPKSC
130 140 150 160 170 180
DTPPPCPRCP EPKSCDTPPP CPRCPEPKSC DTPPPCPRCP APELLGGPSV FLFPPKPKDT
190 200 210 220 230 240
LMISRTPEVT CVVVDVSHED PEVQFKWYVD GVEVHNAKTK PREEQYNSTF RVVSVLTVLH
250 260 270 280 290 300
QDWLNGKEYK CKVSNKALPA PIEKTISKTK GQPREPQVYT LPPSREEMTK NQVSLTCLVK
310 320 330 340 350 360
GFYPSDIAVE WESSGQPENN YNTTPPMLDS DGSFFLYSKL TVDKSRWQQG NIFSCSVMHE
370
ALHNRFTQKS LSLSPGK
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
5 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P01860-1-unknown | ASTKGP... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P01860-114-unknown | CPEPKS... | 114 | unknown | Wildes D. et al: Sampling the N-terminal proteome of human blood | 20173099 | ||||
| P01860-119-unknown | SCDTPP... | 119 | unknown | Wildes D. et al: Sampling the N-terminal proteome of human blood | 20173099 | ||||
| P01860-163-unknown | ELLGGP... | 163 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC23665 | |||
| P01860-165-unknown | LGGPSV... | 165 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC23961 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...RCPAPE | 162 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC23665 | |||
| ...PAPELL | 164 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC23961 | |||
| ...LSPGK | 377 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| MMP3_HUMAN | 162 | PAPE.|.ELLG | inferred from experiment | unknown | MEROPS | Thorpe R | Gearing AJ et al.:Selective cleavage of human IgG... (M10.005) | 11841844, |
| MMP7_HUMAN | 164 | PELL.|.LGGP | inferred from experiment | unknown | MEROPS | Thorpe R | Gearing AJ et al.:Selective cleavage of human IgG... (M10.005) | 11841844, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|