P01861: Immunoglobulin heavy constant gamma 4 {ECO:0000303|PubMed:11340299, ECO:0000303|Ref.5}
| Protein names | - Immunoglobulin heavy constant gamma 4 {ECO:0000303|PubMed:11340299, ECO:0000303|Ref.5} - Ig gamma-4 chain C region {ECO:0000305} |
|---|---|
| Gene names | IGHG4 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | P01861 |
3
N-termini
3
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
ASTKGPSVFP LAPCSRSTSE STAALGCLVK DYFPEPVTVS WNSGALTSGV HTFPAVLQSS
70 80 90 100 110 120
GLYSLSSVVT VPSSSLGTKT YTCNVDHKPS NTKVDKRVES KYGPPCPSCP APEFLGGPSV
130 140 150 160 170 180
FLFPPKPKDT LMISRTPEVT CVVVDVSQED PEVQFNWYVD GVEVHNAKTK PREEQFNSTY
190 200 210 220 230 240
RVVSVLTVLH QDWLNGKEYK CKVSNKGLPS SIEKTISKAK GQPREPQVYT LPPSQEEMTK
250 260 270 280 290 300
NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPVLDS DGSFFLYSRL TVDKSRWQEG
310 320
NVFSCSVMHE ALHNHYTQKS LSLSLGK
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
3 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P01861-1-unknown | ASTKGP... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P01861-113-unknown | EFLGGP... | 113 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC23666 | |||
| P01861-115-unknown | LGGPSV... | 115 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC23962 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...SCPAPE | 112 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC23666 | |||
| ...PAPEFL | 114 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC23962 | |||
| ...LSLGK | 327 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| MMP3_HUMAN | 112 | PAPE.|.EFLG | inferred from experiment | unknown | MEROPS | Thorpe R | Gearing AJ et al.:Selective cleavage of human IgG... (M10.005) | 11841844, |
| MMP7_HUMAN | 114 | PEFL.|.LGGP | inferred from experiment | unknown | MEROPS | Thorpe R | Gearing AJ et al.:Selective cleavage of human IgG... (M10.005) | 11841844, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|