TopFIND 4.0

P02563: Myosin-6

General Information

Protein names
- Myosin-6
- Myosin heavy chain 6
- Myosin heavy chain, cardiac muscle alpha isoform
- MyHC-alpha
Gene names Myh6
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID P02563

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MTDAQMADFG AARYLRKSEK ERLEAQTRPF DIRTECFVPD DKEEYVKAKI VSREGGKVTA 
        70         80         90        100        110        120 
ETENGKTVTV KEDQVMQQNP PKFDKIEDMA MLTFLHEPAV LYNLKERYAA WMIYTYSGLF 
       130        140        150        160        170        180 
CVTVNPYKWL PVYNAEVVAA YRGKKRSEAP PHIFSISDNA YQYMLTDREN QSILITGESG 
       190        200        210        220        230        240 
AGKTVNTKRV IQYFASIAAI GDRSKKDNPN ANKGTLEDQI IQANPALEAF GNAKTVRNDN 
       250        260        270        280        290        300 
SSRFGKFIRI HFGATGKLAS ADIETYLLEK SRVIFQLKAE RNYHIFYQIL SNKKPELLDM 
       310        320        330        340        350        360 
LLVTNNPYDY AFVSQGEVSV ASIDDSEELL ATDSAFDVLG FTAEEKAGVY KLTGAIMHYG 
       370        380        390        400        410        420 
NMKFKQKQRE EQAEPDGTED ADKSAYLMGL NSADLLKGLC HPRVKVGNEY VTKGQSVQQV 
       430        440        450        460        470        480 
YYSIGALAKS VYEKMFNWMV TRINATLETK QPRQYFIGVL DIAGFEIFDF NSFEQLCINF 
       490        500        510        520        530        540 
TNEKLQQFFN HHMFVLEQEE YKKEGIEWEF IDFGMDLQAC IDLIEKPMGI MSILEEECMF 
       550        560        570        580        590        600 
PKATDMTFKA KLYDNHLGKS NNFQKPRNVK GKQEAHFSLV HYAGTVDYNI LGWLEKNKDP 
       610        620        630        640        650        660 
LNETVVGLYQ KSSLKLMATL FSTYASADTG DSGKGKGGKK KGSSFQTVSA LHRENLNKLM 
       670        680        690        700        710        720 
TNLRTTHPHF VRCIIPNERK APGVMDNPLV MHQLRCNGVL EGIRICRKGF PNRILYGDFR 
       730        740        750        760        770        780 
QRYRILNPAA IPEGQFIDSG KGAEKLLGSL DIDHNQYKFG HTKVFFKAGL LGLLEEMRDE 
       790        800        810        820        830        840 
RLSRIITRIQ AQARGQLMRI EFKKMVERRD ALLVIQWNIR AFMGVKNWPW MKLYFKIKPL 
       850        860        870        880        890        900 
LKSAETEKEM ANMKEEFGRV KDALEKSEAR RKELEEKMVS LLQEKNDLQL QVQAEQDNLA 
       910        920        930        940        950        960 
DAEERCDQLI KNKIQLEAKV KEMTERLEDE EEMNAELTAK KRKLEDECSE LKKDIDDLEL 
       970        980        990       1000       1010       1020 
TLAKVEKEKH ATENKVKNLT EEMAGLDEII AKLTKEKKAL QEAHQQALDD LQAEEDKVNT 
      1030       1040       1050       1060       1070       1080 
LTKSKVKLEQ QVDDLEGSLE QEKKVRMDLE RAKRKLEGDL KLTQESIMDL ENDKLQLEEK 
      1090       1100       1110       1120       1130       1140 
LKKKEFDISQ QNSKIEDEQA LALQLQKKLK ENQARIEELE EELEAERTAR AKVEKLRSDL 
      1150       1160       1170       1180       1190       1200 
TRELEEISER LEEAGGATSV QIEMNKKREA EFQKMRRDLE EATLQHEATA AALRKKHADS 
      1210       1220       1230       1240       1250       1260 
VAELGEQIDN LQRVKQKLEK EKSEFKLELD DVTSHMEQII KAKANLEKVS RTLEDQANEY 
      1270       1280       1290       1300       1310       1320 
RVKLEEAQRS LNDFTTQRAK LQTENGELAR QLEEKEALIW QLTRGKLSYT QQMEDLKRQL 
      1330       1340       1350       1360       1370       1380 
EEEGKAKNAL AHALQSARHD CDLLREQYEE EMEAKAELQR VLSKANSEVA QWRTKYETDA 
      1390       1400       1410       1420       1430       1440 
IQRTEELEEA KKKLAQRLQD AEEAVEAVNA KCSSLEKTKH RLQNEIEDLM VDVERSNAAA 
      1450       1460       1470       1480       1490       1500 
AALDKKQRNF DKILAEWKQK YEESQSELES SQKEARSLST ELFKLKNAYE ESLEHLETFK 
      1510       1520       1530       1540       1550       1560 
RENKNLQEEI SDLTEQLGEG GKNVHELEKI RKQLEVEKLE LQSALEEAEA SLEHEEGKIL 
      1570       1580       1590       1600       1610       1620 
RAQLEFNQIK AEIERKLAEK DEEMEQAKRN HLRVVDSLQT SLDAETRSRN EALRVKKKME 
      1630       1640       1650       1660       1670       1680 
GDLNEMEIQL SQANRIASEA QKHLKNAQAH LKDTQLQLDD AVRANDDLKE NIAIVERRNT 
      1690       1700       1710       1720       1730       1740 
LLQAELEELR AVVEQTERSR KLAEQELIET SERVQLLHSQ NTSLINQKKK MDADLSQLQT 
      1750       1760       1770       1780       1790       1800 
EVEEAVQECR NAEEKAKKAI TDAAMMAEEL KKEQDTSAHL ERMKKNMEQT IKDLQHRLDE 
      1810       1820       1830       1840       1850       1860 
AEQIALKGGK KQLQKLEARV RELENELEAE QKRNAESVKG MRKSERRIKE LTYQTEEDKK 
      1870       1880       1890       1900       1910       1920 
NLVRLQDLVD KLQLKVKAYK RQAEEAEEQA NTNLSKFRKV QHELDEAEER ADIAESQVNK 
      1930    
LRAKSRDIGA KQKMHDEE

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P02563-1-unknown MTDAQM... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...MHDEE 1938 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)