TopFIND 4.0

P02652: Apolipoprotein A-II

General Information

Protein names	- Apolipoprotein A-II - Apo-AII - ApoA-II - Apolipoprotein A2 - Proapolipoprotein A-II - ProapoA-II - Truncated apolipoprotein A-II - Apolipoprotein A-II(1-76)
Gene names	APOA2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P02652

7

N-termini

5

C-termini

1

Cleavages

0

Substrates

Sequence

10 20 30 40 50 60
MKLLAATVLL LTICSLEGAL VRRQAKEPCV ESLVSQYFQT VTDYGKDLME KVKSPELQAE
70 80 90 100
AKSYFEKSKE QLTPLIKKAG TELVNFLSYF VELGTQPATQ

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

7 N-termini - 5 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P02652-19-unknown	ALVRRQ...	19		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P02652-24-Pyrrolidone carboxylic acid	QAKEPC...	24	pyrrolidone carboxylic acid-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P02652-37-unknown	YFQTVT...	37			unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02652-42-unknown	TDYGKD...	42		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8649
P02652-49-unknown	MEKVKS...	49		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000476662
P02652-49-unknown	MEKVKS...	49		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000476890
P02652-52-unknown	VKSPEL...	52			unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
P02652-68-unknown	SKEQLT...	68			unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...YFQTVT	41	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8649
	...KSYFEK	66	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000476605
	...VELGTQ	95	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000476740
	...TQPATQ	99	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...QPATQ	100	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
ELNE_HUMAN	41	QTVT.\|.TDYG	inferred from experiment	unknown	MEROPS	Scanu AM	Byrne RE et al.:The enzyme that cleaves apolipo... (S01.131)	6438100,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)