TopFIND 4.0

P02708: Acetylcholine receptor subunit alpha

General Information

Protein names
- Acetylcholine receptor subunit alpha
Gene names CHRNA1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P02708

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEPWPLLLLF SLCSAGLVLG SEHETRLVAK LFKDYSSVVR PVEDHRQVVE VTVGLQLIQL 
        70         80         90        100        110        120 
INVDEVNQIV TTNVRLKQGD MVDLPRPSCV TLGVPLFSHL QNEQWVDYNL KWNPDDYGGV 
       130        140        150        160        170        180 
KKIHIPSEKI WRPDLVLYNN ADGDFAIVKF TKVLLQYTGH ITWTPPAIFK SYCEIIVTHF 
       190        200        210        220        230        240 
PFDEQNCSMK LGTWTYDGSV VAINPESDQP DLSNFMESGE WVIKESRGWK HSVTYSCCPD 
       250        260        270        280        290        300 
TPYLDITYHF VMQRLPLYFI VNVIIPCLLF SFLTGLVFYL PTDSGEKMTL SISVLLSLTV 
       310        320        330        340        350        360 
FLLVIVELIP STSSAVPLIG KYMLFTMVFV IASIIITVIV INTHHRSPST HVMPNWVRKV 
       370        380        390        400        410        420 
FIDTIPNIMF FSTMKRPSRE KQDKKIFTED IDISDISGKP GPPPMGFHSP LIKHPEVKSA 
       430        440        450        460        470        480 
IEGIKYIAET MKSDQESNNA AAEWKYVAMV MDHILLGVFM LVCIIGTLAV FAGRLIELNQ 
   
QG

Isoforms

- Isoform 1 of Acetylcholine receptor subunit alpha

Sequence View

        10         20         30         40         50         60 
MEPWPLLLLF SLCSAGLVLG SEHETRLVAK LFKDYSSVVR PVEDHRQVVE VTVGLQLIQL 
        70         80         90        100        110        120 
INVDEVNQIV TTNVRLKQGD MVDLPRPSCV TLGVPLFSHL QNEQWVDYNL KWNPDDYGGV 
       130        140        150        160        170        180 
KKIHIPSEKI WRPDLVLYNN ADGDFAIVKF TKVLLQYTGH ITWTPPAIFK SYCEIIVTHF 
       190        200        210        220        230        240 
PFDEQNCSMK LGTWTYDGSV VAINPESDQP DLSNFMESGE WVIKESRGWK HSVTYSCCPD 
       250        260        270        280        290        300 
TPYLDITYHF VMQRLPLYFI VNVIIPCLLF SFLTGLVFYL PTDSGEKMTL SISVLLSLTV 
       310        320        330        340        350        360 
FLLVIVELIP STSSAVPLIG KYMLFTMVFV IASIIITVIV INTHHRSPST HVMPNWVRKV 
       370        380        390        400        410        420 
FIDTIPNIMF FSTMKRPSRE KQDKKIFTED IDISDISGKP GPPPMGFHSP LIKHPEVKSA 
       430        440        450        460        470        480 
IEGIKYIAET MKSDQESNNA AAEWKYVAMV MDHILLGVFM LVCIIGTLAV FAGRLIELNQ 
   
QG



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P02708-1-unknown MEPWPL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt66152
    P02708-21-unknown SEHETR... 21 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P02708-21-unknown SEHETR... 21 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt112646

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LNQQG 482 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LNQQG 482 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt61770

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)