P02746: Complement C1q subcomponent subunit B

General Information

Protein names	- Complement C1q subcomponent subunit B
Gene names	C1QB
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P02746

4 N-termini

5 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MMMKIPWGSI PVLMLLLLLG LIDISQAQLS CTGPPAIPGI PGIPGTPGPD GQPGTPGIKG
        70         80         90        100        110        120
EKGLPGLAGD HGEFGEKGDP GIPGNPGKVG PKGPMGPKGG PGAPGAPGPK GESGDYKATQ
       130        140        150        160        170        180
KIAFSATRTI NVPLRRDQTI RFDHVITNMN NNYEPRSGKF TCKVPGLYYF TYHASSRGNL
       190        200        210        220        230        240
CVNLMRGRER AQKVVTFCDY AYNTFQVTTG GMVLKLEQGE NVFLQATDKN SLLGMEGANS
       250
IFSGFLLFPD MEA

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 5 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
P02746-3-unknown	MKIPWG...	3		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000426317
P02746-3-unknown	MKIPWG...	3		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000423689
P02746-3-unknown	MKIPWG...	3		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000404606
P02746-28-Pyrrolidone carboxylic acid	QLSCTG...	28	pyrrolidone carboxylic acid-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P02746-52-unknown	QPGTPG...	52		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC22208
P02746-116-unknown	YKATQK...	116		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23731
P02746-116-unknown	YKATQK...	116		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC22209

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PGPDGQ	51	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC22208
...GESGDY	115	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23731
...GESGDY	115	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC22209
...NNYEPR	155	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000426317
...ATDKNS	230	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000404606
...PDMEA	253	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_HUMAN	51	PDGQ.\|.QPGT	inferred from experiment	unknown	MEROPS	Tenner AJ	Ruiz S et al.:Digestion of C1q collagen-like ... (M10.001)	10496311,
MMP3_HUMAN	115	SGDY.\|.YKAT	inferred from experiment	unknown	MEROPS	Tenner AJ	Ruiz S et al.:Digestion of C1q collagen-like ... (M10.001)	10496311,
MMP2_HUMAN	115	SGDY.\|.YKAT	inferred from experiment	unknown	MEROPS	Tenner AJ	Ruiz S et al.:Digestion of C1q collagen-like ... (M10.001)	10496311,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)