TopFIND 4.0

P02773: Alpha-fetoprotein

General Information

Protein names
- Alpha-fetoprotein
- Alpha-1-fetoprotein
- Alpha-fetoglobulin
Gene names Afp
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID P02773

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKQPATMKWS ASISFLLLLN FAEPRVLHTN EFGIESTLDS SQCPTEKNMF NVATIVVAQF 
        70         80         90        100        110        120 
VQDATKAEVN KMSSDALAAM KENTGDGCLE NQLSVFLDEI CHETELSNKY GFSGCCNQSG 
       130        140        150        160        170        180 
VERHQCLLAR KKTAPDSVPP FHFPETAESC PAYEENRAMS INTFIYDVSK RNPFLYAPTI 
       190        200        210        220        230        240 
LYLAAQYDKA VPACCKADNM EECFQTKRAS MAKELREGSM LNEHVCAVIR KFGSRNLQAV 
       250        260        270        280        290        300 
LIIKLSQKFP KANITEIRKL ALDVAHIHEQ CCHGNAMECL QDGESVMTHM CSQQEILSSK 
       310        320        330        340        350        360 
TAECCKLPTI ELGYCIIHAE NGDKPEGLTL NPSEFLGDRN FAQFSSEEKL LFMASFLHEY 
       370        380        390        400        410        420 
SRNHPNLPVS VILKTAKSYQ EILEKCSQSE TPSKCQDNME EELQKHIQES QALAKQSCNL 
       430        440        450        460        470        480 
YQKLGPYYLQ NLFLIGYTRK APQLTSAELI DLTGKMVSIA STCCQLSEEK RSACGEGLAD 
       490        500        510        520        530        540 
IYIGHLCLRH EANPVNSGIN HCCSSSYSNR RLCITSFLRD ETYVPPPFSE DKFIFHKDLC 
       550        560        570        580        590        600 
QAQGRALQTM KQELLINLVK QKPEMTEEQH AAVTADFSGL LEKCCKDQDQ EACFAKEGPK 
       610    
LISKTREALG V

Isoforms

- Isoform 2 of Alpha-fetoprotein

Sequence View

        10         20         30         40         50         60 
MKQPATMKWS ASISFLLLLN FAEPRVLHTN EFGIESTLDS SQCPTEKNMF NVATIVVAQF 
        70         80         90        100        110        120 
VQDATKAEVN KMSSDALAAM KENTGDGCLE NQLSVFLDEI CHETELSNKY GFSGCCNQSG 
       130        140        150        160        170        180 
VERHQCLLAR KKTAPDSVPP FHFPETAESC PAYEENRAMS INTFIYDVSK RNPFLYAPTI 
       190        200        210        220        230        240 
LYLAAQYDKA VPACCKADNM EECFQTKRAS MAKELREGSM LNEHVCAVIR KFGSRNLQAV 
       250        260        270        280        290        300 
LIIKLSQKFP KANITEIRKL ALDVAHIHEQ CCHGNAMECL QDGESVMTHM CSQQEILSSK 
       310        320        330        340        350        360 
TAECCKLPTI ELGYCIIHAE NGDKPEGLTL NPSEFLGDRN FAQFSSEEKL LFMASFLHEY 
       370        380        390        400        410        420 
SRNHPNLPVS VILKTAKSYQ EILEKCSQSE TPSKCQDNME EELQKHIQES QALAKQSCNL 
       430        440        450        460        470        480 
YQKLGPYYLQ NLFLIGYTRK APQLTSAELI DLTGKMVSIA STCCQLSEEK RSACGEGLAD 
       490        500        510        520        530        540 
IYIGHLCLRH EANPVNSGIN HCCSSSYSNR RLCITSFLRD ETYVPPPFSE DKFIFHKDLC 
       550        560        570        580        590        600 
QAQGRALQTM KQELLINLVK QKPEMTEEQH AAVTADFSGL LEKCCKDQDQ EACFAKEGPK 
       610    
LISKTREALG V



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P02773-25-unknown RVLHTN... 25 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P02773-287-unknown MTHMCS... 287 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt192634

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...EALGV 611 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...EALGV 611 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt152580

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)