P03372: Estrogen receptor

General Information

Protein names	- Estrogen receptor - ER - ER-alpha - Estradiol receptor - Nuclear receptor subfamily 3 group A member 1
Gene names	ESR1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P03372

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MTMTLHTKAS GMALLHQIQG NELEPLNRPQ LKIPLERPLG EVYLDSSKPA VYNYPEGAAY
        70         80         90        100        110        120
EFNAAAAANA QVYGQTGLPY GPGSEAAAFG SNGLGGFPPL NSVSPSPLML LHPPPQLSPF
       130        140        150        160        170        180
LQPHGQQVPY YLENEPSGYT VREAGPPAFY RPNSDNRRQG GRERLASTND KGSMAMESAK
       190        200        210        220        230        240
ETRYCAVCND YASGYHYGVW SCEGCKAFFK RSIQGHNDYM CPATNQCTID KNRRKSCQAC
       250        260        270        280        290        300
RLRKCYEVGM MKGGIRKDRR GGRMLKHKRQ RDDGEGRGEV GSAGDMRAAN LWPSPLMIKR
       310        320        330        340        350        360
SKKNSLALSL TADQMVSALL DAEPPILYSE YDPTRPFSEA SMMGLLTNLA DRELVHMINW
       370        380        390        400        410        420
AKRVPGFVDL TLHDQVHLLE CAWLEILMIG LVWRSMEHPG KLLFAPNLLL DRNQGKCVEG
       430        440        450        460        470        480
MVEIFDMLLA TSSRFRMMNL QGEEFVCLKS IILLNSGVYT FLSSTLKSLE EKDHIHRVLD
       490        500        510        520        530        540
KITDTLIHLM AKAGLTLQQQ HQRLAQLLLI LSHIRHMSNK GMEHLYSMKC KNVVPLYDLL
       550        560        570        580        590
LEMLDAHRLH APTSRGGASV EETDQSHLAT AGSTSSHSLQ KYYITGEAEG FPATV

Isoforms

- Isoform 2 of Estrogen receptor - Isoform 3 of Estrogen receptor - Isoform 4 of Estrogen receptor

Sequence View

        10         20         30         40         50         60
MTMTLHTKAS GMALLHQIQG NELEPLNRPQ LKIPLERPLG EVYLDSSKPA VYNYPEGAAY
        70         80         90        100        110        120
EFNAAAAANA QVYGQTGLPY GPGSEAAAFG SNGLGGFPPL NSVSPSPLML LHPPPQLSPF
       130        140        150        160        170        180
LQPHGQQVPY YLENEPSGYT VREAGPPAFY RPNSDNRRQG GRERLASTND KGSMAMESAK
       190        200        210        220        230        240
ETRYCAVCND YASGYHYGVW SCEGCKAFFK RSIQGHNDYM CPATNQCTID KNRRKSCQAC
       250        260        270        280        290        300
RLRKCYEVGM MKGGIRKDRR GGRMLKHKRQ RDDGEGRGEV GSAGDMRAAN LWPSPLMIKR
       310        320        330        340        350        360
SKKNSLALSL TADQMVSALL DAEPPILYSE YDPTRPFSEA SMMGLLTNLA DRELVHMINW
       370        380        390        400        410        420
AKRVPGFVDL TLHDQVHLLE CAWLEILMIG LVWRSMEHPG KLLFAPNLLL DRNQGKCVEG
       430        440        450        460        470        480
MVEIFDMLLA TSSRFRMMNL QGEEFVCLKS IILLNSGVYT FLSSTLKSLE EKDHIHRVLD
       490        500        510        520        530        540
KITDTLIHLM AKAGLTLQQQ HQRLAQLLLI LSHIRHMSNK GMEHLYSMKC KNVVPLYDLL
       550        560        570        580        590
LEMLDAHRLH APTSRGGASV EETDQSHLAT AGSTSSHSLQ KYYITGEAEG FPATV         10         20         30         40         50         60
MTMTLHTKAS GMALLHQIQG NELEPLNRPQ LKIPLERPLG EVYLDSSKPA VYNYPEGAAY
        70         80         90        100        110        120
EFNAAAAANA QVYGQTGLPY GPGSEAAAFG SNGLGGFPPL NSVSPSPLML LHPPPQLSPF
       130        140        150        160        170        180
LQPHGQQVPY YLENEPSGYT VREAGPPAFY RPNSDNRRQG GRERLASTND KGSMAMESAK
       190        200        210        220        230        240
ETRYCAVCND YASGYHYGVW SCEGCKAFFK RSIQGHNDYM CPATNQCTID KNRRKSCQAC
       250        260        270        280        290        300
RLRKCYEVGM MKGGIRKDRR GGRMLKHKRQ RDDGEGRGEV GSAGDMRAAN LWPSPLMIKR
       310        320        330        340        350        360
SKKNSLALSL TADQMVSALL DAEPPILYSE YDPTRPFSEA SMMGLLTNLA DRELVHMINW
       370        380        390        400        410        420
AKRVPGFVDL TLHDQVHLLE CAWLEILMIG LVWRSMEHPG KLLFAPNLLL DRNQGKCVEG
       430        440        450        460        470        480
MVEIFDMLLA TSSRFRMMNL QGEEFVCLKS IILLNSGVYT FLSSTLKSLE EKDHIHRVLD
       490        500        510        520        530        540
KITDTLIHLM AKAGLTLQQQ HQRLAQLLLI LSHIRHMSNK GMEHLYSMKC KNVVPLYDLL
       550        560        570        580        590
LEMLDAHRLH APTSRGGASV EETDQSHLAT AGSTSSHSLQ KYYITGEAEG FPATV         10         20         30         40         50         60
MTMTLHTKAS GMALLHQIQG NELEPLNRPQ LKIPLERPLG EVYLDSSKPA VYNYPEGAAY
        70         80         90        100        110        120
EFNAAAAANA QVYGQTGLPY GPGSEAAAFG SNGLGGFPPL NSVSPSPLML LHPPPQLSPF
       130        140        150        160        170        180
LQPHGQQVPY YLENEPSGYT VREAGPPAFY RPNSDNRRQG GRERLASTND KGSMAMESAK
       190        200        210        220        230        240
ETRYCAVCND YASGYHYGVW SCEGCKAFFK RSIQGHNDYM CPATNQCTID KNRRKSCQAC
       250        260        270        280        290        300
RLRKCYEVGM MKGGIRKDRR GGRMLKHKRQ RDDGEGRGEV GSAGDMRAAN LWPSPLMIKR
       310        320        330        340        350        360
SKKNSLALSL TADQMVSALL DAEPPILYSE YDPTRPFSEA SMMGLLTNLA DRELVHMINW
       370        380        390        400        410        420
AKRVPGFVDL TLHDQVHLLE CAWLEILMIG LVWRSMEHPG KLLFAPNLLL DRNQGKCVEG
       430        440        450        460        470        480
MVEIFDMLLA TSSRFRMMNL QGEEFVCLKS IILLNSGVYT FLSSTLKSLE EKDHIHRVLD
       490        500        510        520        530        540
KITDTLIHLM AKAGLTLQQQ HQRLAQLLLI LSHIRHMSNK GMEHLYSMKC KNVVPLYDLL
       550        560        570        580        590
LEMLDAHRLH APTSRGGASV EETDQSHLAT AGSTSSHSLQ KYYITGEAEG FPATV

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P03372-1-unknown	MTMTLH...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P03372-1-unknown	MTMTLH...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt74203
P03372-174-unknown	MAMESA...	174	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt74204
P03372-174-unknown	MAMESA...	174	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt74205
P03372-174-unknown	MAMESA...	174	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt108139

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...FPATV	595	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...FPATV	595	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt69822
...FPATV	595	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt69821

TopFIND

P03372: Estrogen receptor

General Information

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates