TopFIND 4.0

P03953: Complement factor D

General Information

Protein names
- Complement factor D
- 3.4.21.46
- 28 kDa adipocyte protein
- Adipsin
- C3 convertase activator
- Properdin factor D
Gene names Cfd
Organism Mus musculus
Protease Family
Protease ID S01.191
Chromosome location
UniProt ID P03953

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MHSSVYFVAL VILGAAVCAA QPRGRILGGQ EAAAHARPYM ASVQVNGTHV CGGTLLDEQW 
        70         80         90        100        110        120 
VLSAAHCMDG VTDDDSVQVL LGAHSLSAPE PYKRWYDVQS VVPHPGSRPD SLEDDLILFK 
       130        140        150        160        170        180 
LSQNASLGPH VRPLPLQYED KEVEPGTLCD VAGWGVVTHA GRRPDVLHQL RVSIMNRTTC 
       190        200        210        220        230        240 
NLRTYHDGVV TINMMCAESN RRDTCRGDSG SPLVCGDAVE GVVTWGSRVC GNGKKPGVYT 
       250    
RVSSYRMWIE NITNGNMTS

Isoforms

- Isoform 2 of Complement factor D

Sequence View

        10         20         30         40         50         60 
MHSSVYFVAL VILGAAVCAA QPRGRILGGQ EAAAHARPYM ASVQVNGTHV CGGTLLDEQW 
        70         80         90        100        110        120 
VLSAAHCMDG VTDDDSVQVL LGAHSLSAPE PYKRWYDVQS VVPHPGSRPD SLEDDLILFK 
       130        140        150        160        170        180 
LSQNASLGPH VRPLPLQYED KEVEPGTLCD VAGWGVVTHA GRRPDVLHQL RVSIMNRTTC 
       190        200        210        220        230        240 
NLRTYHDGVV TINMMCAESN RRDTCRGDSG SPLVCGDAVE GVVTWGSRVC GNGKKPGVYT 
       250    
RVSSYRMWIE NITNGNMTS



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(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...GNMTS 259 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...GNMTS 259 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt66034

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)